(Q36828108)

English

N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state

scientific article published on December 1, 1991

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state (English)

1 reference

Europe PubMed Central

16 August 2017

post-translational protein modification

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1682507

28 October 2022

1 reference

10.1128/JVI.65.12.6597-6603.1991

https://api.crossref.org/works/10.1128/JVI.65.12.6597-6603.1991

28 October 2022

1 reference

10.1128/JVI.65.12.6597-6603.1991

https://api.crossref.org/works/10.1128/JVI.65.12.6597-6603.1991

28 October 2022

author name string

B. Caughey

1

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28 October 2022

G. J. Raymond

2

1 reference

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28 October 2022

D. Ernst

3

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28 October 2022

R. E. Race

4

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28 October 2022

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publication date

1 December 1991

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16 August 2017

full work available at URL

http://jvi.asm.org/cgi/content/abstract/65/12/6597

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28 October 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1682507/?tool=EBI

online access status

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28 October 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1682507/pdf/?tool=EBI

Portable Document Format

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28 October 2022

https://europepmc.org/articles/PMC250721

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Europe PubMed Central

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1682507

28 October 2022

https://europepmc.org/articles/PMC250721?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1682507

28 October 2022

https://journals.asm.org/doi/pdf/10.1128/jvi.65.12.6597-6603.1991

1 reference

10.1128/JVI.65.12.6597-6603.1991

https://api.crossref.org/works/10.1128/JVI.65.12.6597-6603.1991

28 October 2022

Journal of Virology

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Europe PubMed Central

16 August 2017

65

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Europe PubMed Central

16 August 2017

6597-6603

1 reference

Europe PubMed Central

16 August 2017

12

1 reference

Europe PubMed Central

16 August 2017

Novel proteinaceous infectious particles cause scrapie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Self-replication and scrapie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Does the agent of scrapie replicate without nucleic acid?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Scrapie PrP 27-30 is a sialoglycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Immunoaffinity purification and neutralization of scrapie prion infectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Analyses of frequency of infection, specific infectivity, and prion protein biosynthesis in scrapie-infected neuroblastoma cell clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

In vitro expression in eukaryotic cells of a prion protein gene cloned from scrapie-infected mouse brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Antisera to scrapie-associated fibril protein and prion protein decorate scrapie-associated fibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

A cellular gene encodes scrapie PrP 27-30 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Specific proteins associated with Creutzfeldt-Jakob disease and scrapie share antigenic and carbohydrate determinants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Mechanisms of membrane protein turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Microtubules, membrane traffic, and cell organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Protease sensitivity and nuclease resistance of the scrapie agent propagated in vitro in neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

The Scrapie Agent In Vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

In Vitro Expression and Biosynthesis of Prion Protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Degradation of acetylcholine receptors in muscle cells: effect of leupeptin on turnover rate, intracellular pool sizes, and receptor properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Scrapie: concept of a virus-induced amyloidosis of the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

29 September 2017

Degradation of the acetylcholine receptor in cultured muscle cells: selective inhibitors and the fate of undegraded receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Degradation of surface-labeled hepatoma membrane polypeptides: effect of inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Antibodies to a scrapie prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Scrapie-associated fibrils in Creutzfeldt–Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

The possible nature of the transmissible agent of scrapie.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Identification of prion amyloid filaments in scrapie-infected brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Prion-protein immunoreactivity in human transmissible dementias.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Diagnosis of Creutzfeldt-Jakob disease by Western blot identification of marker protein in human brain tissue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Characterization of scrapie infection in mouse neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Molecular pathology of scrapie-associated fibril protein (PrP) in mouse brain affected by the ME7 strain of scrapie.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Immuno-gold localization of prion filaments in scrapie-infected hamster brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Isolation and structural studies of the intact scrapie agent protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Pathogenesis of scrapie: study of the temporal development of clinical symptoms, of infectivity titres and scrapie-associated fibrils in brains of hamsters infected intraperitoneally.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Scrapie prion protein contains a phosphatidylinositol glycolipid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Virus-induced amyloidosis in scrapie involves a change in covalent linkages in the preamyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Inhibition of the Lysosomal Pathway of Protein Degradation in Isolated Rat Hepatocytes by Ammonia, Methylamine, Chloroquine and Leupeptin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

27 June 2018

Identification of a protein that purifies with the scrapie prion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

5 September 2018

Scrapie infectivity, fibrils and low molecular weight protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

5 September 2018

Scrapie prions aggregate to form amyloid-like birefringent rods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

5 September 2018

A protease-resistant protein is a structural component of the scrapie prion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

5 September 2018

Towards purification of the scrapie agent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

5 September 2018

Purification and properties of the cellular and scrapie hamster prion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

5 September 2018

Antibody to scrapie-associated fibril protein identifies a cellular antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250721

5 September 2018

The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

59 Inhibitors of lysosomal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation and Structure of Gels and Fibrils from Glucagon

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.65.12.6597-6603.1991

0 references

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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