(Q36832869)

16 August 2017

1 reference

title

The CD8 T cell in multiple sclerosis: suppressor cell or mediator of neuropathology? (English)

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16 August 2017

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Aaron J Johnson

1

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16 August 2017

Georgette L Suidan

series ordinal

2

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16 August 2017

Jeremiah McDole

series ordinal

3

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16 August 2017

Istvan Pirko

series ordinal

4

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16 August 2017

publication date

1 January 2007

1 reference

International Review of Neurobiology

16 August 2017

published in

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16 August 2017

volume

79

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16 August 2017

page(s)

73-97

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Astrocyte-endothelial interactions and blood-brain barrier permeability

16 August 2017

cites work

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7 January 2021

Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction

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7 January 2021

Human regulatory T cells and their role in autoimmune disease

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7 January 2021

The blood-brain barrier: an overview: structure, regulation, and clinical implications

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7 January 2021

Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

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7 January 2021

Natural regulatory T cells in infectious disease

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7 January 2021

Glatiramer acetate (GA) therapy induces a focused, oligoclonal CD8+ T-cell repertoire in multiple sclerosis.

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7 January 2021

Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation

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7 January 2021

Interleukin-1beta -induced changes in blood-brain barrier permeability, apparent diffusion coefficient, and cerebral blood volume in the rat brain: a magnetic resonance study.

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7 January 2021

Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis

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7 January 2021

Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations

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7 January 2021

Inflammation and degeneration in multiple sclerosis

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7 January 2021

Massive expansion of antigen-specific CD8+ T cells during an acute virus infection

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7 January 2021

Homing phenotypes of tumor-specific CD8 T cells are predetermined at the tumor site by crosspresenting APCs.

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7 January 2021

Is damage in central nervous system due to inflammation?

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7 January 2021

High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay

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7 January 2021

Compartmentalized coculture of rat brain endothelial cells and astrocytes: a syngenic model to study the blood-brain barrier

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7 January 2021

Glatiramer acetate (Copaxone®) therapy for multiple sclerosis

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7 January 2021

Cutting edge: in vitro-generated tolerogenic APC induce CD8+ T regulatory cells that can suppress ongoing experimental autoimmune encephalomyelitis

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7 January 2021

Impairment of CD8+ T suppressor cell function in patients with active systemic lupus erythematosus

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7 January 2021

Multiple sclerosis: a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Natural killer cells and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Human dendritic cells activated by TSLP and CD40L induce proallergic cytotoxic T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Infectious causes of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Sepsis associated encephalopathy (SAE): a review.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

In search of the astrocytic factor(s) modulating blood-brain barrier functions in brain capillary endothelial cells in vitro

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

The blood-brain barrier/neurovascular unit in health and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Expression of major histocompatibility complex class I molecules on the different cell types in multiple sclerosis lesions.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Analysis of regulatory CD8 T cells in Qa-1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

How the T Cell Repertoire Becomes Peptide and MHC Specific

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Role of CD8+ T cells in murine experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Antigen-specific CD8+ T cells mediate a peptide-induced fatal syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Natural history of multiple sclerosis

1 reference

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7 January 2021

Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Initiation of immune responses in brain is promoted by local dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Herpes Simplex Virus-Specific Memory CD8+ T Cells Are Selectively Activated and Retained in Latently Infected Sensory Ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Intracellular cytokine profile in T-cell subsets of multiple sclerosis patients: different features in primary progressive disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Cytokine producing CD8+ T cells are correlated to MRI features of tissue destruction in MS.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Role of specific CD8+ T cells in the severity of a fulminant zoonotic viral hemorrhagic fever, hantavirus pulmonary syndrome

1 reference

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7 January 2021

Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Activation of T lymphocytes in dengue virus infections. High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2, and interferon-gamma in sera of children with dengue

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Multiple sclerosis in the Faroe Islands: an epitome

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

The CD4-Th1 model for multiple sclerosis: a critical [correction of crucial] re-appraisal

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Strong HLA class I--restricted T cell responses in dengue hemorrhagic fever: a double-edged sword?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Evidence for pathogenic heterogeneity in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Regulatory T cells control autoimmunity in vivo by inducing apoptotic depletion of activated pathogenic lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Immunopathogenesis of the multiple sclerosis lesion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Human cerebral malaria and the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

MHC class I-restricted killing of neurons by virus-specific CD8+ T lymphocytes is effected through the Fas/FasL, but not the perforin pathway,.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Blood-brain barrier disruption in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever

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7 January 2021

Clonal Dominance of CD8+ T‐Cells in Multiple Sclerosis

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7 January 2021

An infectious basis for multiple sclerosis: perspectives on the role of Chlamydia pneumoniae and other agents

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Perforin-dependent neurologic injury in a viral model of multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Regulatory functions of CD8+CD28– T cells in an autoimmune disease model

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Induction of MHC class I genes in neurons

1 reference

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7 January 2021

Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases.

1 reference

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7 January 2021

Myelin-specific tolerance attenuates the progression of a virus-induced demyelinating disease: implications for the treatment of MS.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

CD8+ T cell-mediated HLA-A*0201-restricted cytotoxicity to transaldolase peptide 168-176 in patients with multiple sclerosis

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

1 reference

7 January 2021

Theiler's virus infection: a model for multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Interferon-gamma and interleukin-10 reciprocally regulate endothelial junction integrity and barrier function.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Low interleukin-10 production is associated with higher disability and MRI lesion load in secondary progressive multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Junctional complexes of the blood-brain barrier: permeability changes in neuroinflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Association between peripheral IFN-γ producing CD8+ T-cells and disability score in relapsing-remitting multiple sclerosis

1 reference

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7 January 2021

Increased adhesion molecule and chemokine receptor expression on CD8+ T cells trafficking to cerebrospinal fluid in HIV-1 infection.

1 reference

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7 January 2021

Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood

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7 January 2021

Neurological manifestations of dengue infection

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7 January 2021

Virtues and pitfalls of EAE for the development of therapies for multiple sclerosis

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

A single T cell receptor recognizes structurally distinct MHC/peptide complexes with high specificity

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Viruses can silently prime for and trigger central nervous system autoimmune disease

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Structural and signalling molecules come together at tight junctions

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Preservation of neurologic function during inflammatory demyelination correlates with axon sparing in a mouse model of multiple sclerosis

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Multiple sclerosis is an inflammatory T-cell-mediated autoimmune disease

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Neuromyelitis optica: current concepts

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

The clinical course of neuromyelitis optica (Devic's syndrome).

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Revised diagnostic criteria for neuromyelitis optica

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Tight junctions of the blood-brain barrier: development, composition and regulation

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Cytokines, nitric oxide, and cGMP modulate the permeability of an in vitro model of the human blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

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https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

The T lymphocyte in experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Increased CD8+ cytotoxic T cell responses to myelin basic protein in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

T cell responses to an HLA-B*07-restricted epitope on the dengue NS3 protein correlate with disease severity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2807%2979004-9

7 January 2021

10.1016/S0074-7742(07)79004-9

Identifiers

DOI

1 reference

16 August 2017

1 reference