(Q36841034)

16 August 2017

1 reference

title

Assessment of safety/risk of chemicals: inception and evolution of the ADI and dose-response modeling procedures (English)

1 reference

dose-response relationship

16 August 2017

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1755034

16 November 2022

author name string

Sielken RL Jr

2

1 reference

16 August 2017

F. C. Lu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1755034

16 November 2022

R. L. Sielken

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1755034

16 November 2022

language of work or name

1 reference

1 December 1991

1 reference

full work available at URL

16 August 2017

https://api.elsevier.com/content/article/PII:0378427491900528?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

https://api.elsevier.com/content/article/PII:0378427491900528?httpAccept=text/plain

16 November 2022

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

16 November 2022

1 reference

16 August 2017

volume

59

1 reference

16 August 2017

issue

1-3

1 reference

16 August 2017

page(s)

5-40

1 reference

The role of biomarkers in reproductive and developmental toxicology

16 August 2017

cites work

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1 reference

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Methylmercury Poisoning in Iraq

16 November 2022

18

1 reference

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Revision of the Total Diet Study food list and diets

16 November 2022

21

1 reference

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EVALUATION OF THE TOXICITY OF A NUMBER OF ANTIMICROBIALS AND ANTIOXIDANTS

16 November 2022

29

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A new approach to deriving community exposure guidelines from "no-observed-adverse-effect levels".

16 November 2022

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Specifications for the identity and purity of food additives and their toxicological evaluation: some flavouring substances and non-nutritive sweetening agents

16 November 2022

32

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Reconsideration of the dilemma of DDT for the establishment of an acceptable daily intake

16 November 2022

35

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Reference dose (RfD): description and use in health risk assessments

16 November 2022

36

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Regulatory history and experimental support of uncertainty (safety) factors

16 November 2022

37

1 reference

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Reference dose (RfD): description and use in health risk assessments

16 November 2022

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Drinking water standards and risk assessment.

16 November 2022

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Acceptable daily intake: Inception, evolution, and application

16 November 2022

44

1 reference

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Toxicological evaluation of certain food additives with a review of general principles and of specifications

16 November 2022

49

1 reference

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Risk assessment of carcinogenic and noncarcinogenic chemicals

16 November 2022

55

1 reference

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A review of the dietary intakes of chemical contaminants

16 November 2022

64

1 reference

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Estimation of risks of irreversible, delayed toxicity

16 November 2022

66

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

The no-effect level, an old bone of contention in toxicology

16 November 2022

67

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Risk assessment and regulatory decision making

16 November 2022

69

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

A new method for determining allowable daily intakes.

16 November 2022

70

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Safety assessments of chemicals with thresholded effects.

16 November 2022

72

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

The role of biomarkers in reproductive and developmental toxicology

16 November 2022

77

1 reference

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Quantitative risk assessment

16 November 2022

82

1 reference

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The Multistage Theory of Carcinogenesis and the Age Distribution of Cancer in Man2

16 November 2022

85

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Carcinogenic risk assessment.

16 November 2022

86

1 reference

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A comparison of statistical methods for low dose extrapolation utilizing time-to-tumor data

16 November 2022

87

1 reference

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A stochastic two-stage model for cancer risk assessment. I. The hazard function and the probability of tumor.

16 November 2022

92

1 reference

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A stochastic two-stage model for cancer risk assessment. II. The number and size of premalignant clones

16 November 2022

93

1 reference

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Cell proliferation in carcinogenesis

16 November 2022

94

1 reference

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Biologically motivated cancer risk models.

16 November 2022

95

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Determining "safe" levels of exposure: safety factors or mathematical models?

16 November 2022

109

1 reference

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Important recent advances in the practice of health risk assessment: implications for the 1990s

16 November 2022

116

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Food and Drug Administration Advisory Committee on Protocols for Safety Evaluation: Panel on carcinogenesis report on cancer testing in the safety evaluation of food additives and pesticides *1, *2August, 1970

16 November 2022

119

1 reference

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Quantitative cancer risk assessments for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

16 November 2022

120

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

A critical evaluation of a dose-response assessment for TCDD

16 November 2022

121

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

The importance of delivered dose in estimating low-dose cancer risk from inhalation exposure to formaldehyde

16 November 2022

124

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Preliminary estimates of the virtually safe dose for tumors obtained from the maximum tolerated dose

16 November 2022

125

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Recent developments in carcinogenic risk assessment

16 November 2022

126

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Implication of nonlinear kinetics on risk estimation in carcinogenesis.

16 November 2022

131

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Six common errors relating to environmental pollution

16 November 2022

133

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Too many rodent carcinogens: mitogenesis increases mutagenesis

16 November 2022

134

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Physiologically based pharmacokinetics and the risk assessment process for methylene chloride.

16 November 2022

139

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Pharmacokinetics in low dose extrapolation using animal cancer data.

16 November 2022

141

1 reference

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ES Series: Cancer Risk Assessment. 2. Physiological pharmacokinetic modeling

16 November 2022

142

1 reference

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Physiologically based pharmacokinetic modeling with methylchloroform: implications for interspecies, high dose/low dose, and dose route extrapolations.

16 November 2022

143

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

The assessment of low-dose carcinogenicity

16 November 2022

144

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Interspecific Scaling of Toxicity Data

16 November 2022

145

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Uncertainty in risk assessment

16 November 2022

147

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Mathematical models in quantitative assessment of carcinogenic risk.

16 November 2022

148

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

Expert scientific judgment and cancer risk assessment: a pilot study of pharmacokinetic data

16 November 2022

150

1 reference

https://api.crossref.org/works/10.1016/0378-4274(91)90052-8

16 November 2022

Identifiers

1 reference

16 August 2017

1 reference