(Q36844950)

16 August 2017

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title

Targeting costimulatory pathways for tumor immunotherapy (English)

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16 August 2017

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Robert C Ward

1

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16 August 2017

Howard L Kaufman

series ordinal

2

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16 August 2017

publication date

1 May 2007

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International Reviews of Immunology

16 August 2017

published in

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16 August 2017

volume

26

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16 August 2017

issue

3-4

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16 August 2017

page(s)

161-196

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Effector memory T cells, early metastasis, and survival in colorectal cancer

16 August 2017

cites work

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Does the immune system see tumors as foreign or self?

21 January 2018

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Cancer regression in patients after transfer of genetically engineered lymphocytes

21 January 2018

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Structural mechanisms of costimulation

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

Activation and inhibition of lymphocytes by costimulation

21 January 2018

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Emerging paradigms of T-cell co-stimulation.

21 January 2018

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The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.

21 January 2018

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Spinning molecular immunology into successful immunotherapy

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

The CD2-subset of the Ig superfamily of cell surface molecules: receptor-ligand pairs expressed by NK cells and other immune cells

21 January 2018

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Integrins and T cell-mediated immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

T-cell tolerance or function is determined by combinatorial costimulatory signals

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

The interaction properties of costimulatory molecules revisited.

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

21 January 2018

The B7 family revisited

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https://api.crossref.org/works/10.1080%2F08830180701365941

CD28/B7 system of T cell costimulation

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

Vav-family proteins in T-cell signalling

21 January 2018

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21 January 2018

The B7-CD28 superfamily

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https://api.crossref.org/works/10.1080%2F08830180701365941

Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

Targeting the local tumor microenvironment with vaccinia virus expressing B7.1 for the treatment of melanoma

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

Principles and use of anti-CTLA4 antibody in human cancer immunotherapy

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180701365941

Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a phase I/II study

21 January 2018

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Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

TNF/TNFR family members in costimulation of T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Anti-CD 40 monoclonal antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

The TNF superfamily members LIGHT and CD154 (CD40 ligand) costimulate induction of dendritic cell maturation and elicit specific CTL activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Immune properties of recombinant vaccinia virus encoding CD154 (CD40L) are determined by expression of virally encoded CD40L and the presence of CD40L protein in viral particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Transgenic expression of CD40L and interleukin-2 induces an autologous antitumor immune response in patients with non-Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

CD27 is required for generation and long-term maintenance of T cell immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

OX40 ligand-transduced tumor cell vaccine synergizes with GM-CSF and requires CD40-Apc signaling to boost the host T cell antitumor response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Immunostimulatory monoclonal antibodies for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

4-1BB ligand enhances tumor-specific immunity of poxvirus vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

CD30-governor of memory T cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Molecular interactions mediating T cell antigen recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

The immunological synapse: integrins take the stage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Ras initiates phosphatidyl-inositol-3-kinase (PI3K)/PKB mediated signalling pathways in untransformed human peripheral blood T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

ICAM-1 co-stimulates target cells to facilitate antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

From rolling to arrest on blood vessels: leukocyte tap dancing on endothelial integrin ligands and chemokines at sub-second contacts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Rearrangement of integrins in avidity regulation by leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Small cytokine superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

The biology of chemokines and their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Chemokines and T lymphocytes: more than an attraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Chemokines as regulators of T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Activation of G-protein-coupled receptors: a common molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

The role of chemokine receptors in primary, effector, and memory immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Chemokines in tumor immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

RANTES secretion by gene-modified tumor cells results in loss of tumorigenicity in vivo: role of immune cell subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Local delivery of recombinant vaccinia virus expressing secondary lymphoid chemokine (SLC) results in a CD4 T-cell dependent antitumor response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Costimulatory molecules as adjuvants for immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Manipulating the local tumor microenvironment with poxviruses expressing costimulatory molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

TRICOM: enhanced vaccines as anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

A recombinant vector expressing transgenes for four T-cell costimulatory molecules (OX40L, B7-1, ICAM-1, LFA-3) induces sustained CD4+ and CD8+ T-cell activation, protection from apoptosis, and enhanced cytokine production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Anti-tumor immunity elicited by a recombinant vaccinia virus expressing CD70 (CD27L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

Tuning tumor-specific T-cell activation: a matter of costimulation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180701365941

10.1080/08830180701365941

21 January 2018

Identifiers

DOI

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16 August 2017

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