(Q36846693)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22867001%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Design, synthesis, and evaluation of pH-dependent hydrolyzable emetine analogues as treatment for prostate cancer (English)

1 reference

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10 February 2020

1 reference

4

1 reference

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10 February 2020

author name string

Emmanuel S Akinboye

1

1 reference

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10 February 2020

Marc D Rosen

2

1 reference

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10 February 2020

Samuel R Denmeade

3

1 reference

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10 February 2020

Oladapo Bakare

5

1 reference

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10 February 2020

language of work or name

English

0 references

publication date

16 August 2012

1 reference

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Journal of Medicinal Chemistry

10 February 2020

published in

1 reference

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10 February 2020

volume

55

1 reference

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10 February 2020

issue

17

1 reference

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10 February 2020

page(s)

7450-7459

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10 February 2020

cites work

Cancer statistics, 2010

1 reference

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Poly(amidoamine) conjugates containing doxorubicin bound via an acid-sensitive linker

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

Chemical genetics: elucidating biological systems with small-molecule compounds

29 September 2017

1 reference

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Isothiocyanates from tosyl chloride mediated decomposition of in situ generated dithiocarbamic acid salts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

Structural basis for inhibition of protein synthesis by emetine and cycloheximide based on an analogy between ipecac alkaloids and glutarimide antibiotics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

pH-Responsive copolymer assemblies for controlled release of doxorubicin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

29 September 2017

Cancer statistics, 2001

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

Target-oriented and diversity-oriented organic synthesis in drug discovery

29 September 2017

1 reference

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Reversible blocking of peptide amino groups by maleic anhydride

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

Strategy and tactics in protein chemistry

29 September 2017

1 reference

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Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

29 September 2017

1 reference

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Whatever happened to NSC--? An analysis of clinical results of discontinued anticancer agents.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

The chemotherapy of amoebiasis

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

Reversible blocking of amino groups with citraconic anhydride

27 June 2018

1 reference

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pH distribution in human tumors.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

Isomer-dependent daunomycin release and in vitro antitumour effect of cis-aconityl-daunomycin

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

HPMA copolymers with pH-controlled release of doxorubicin: in vitro cytotoxicity and in vivo antitumor activity

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

The use of maleic anhydride for the reversible blocking of amino groups in polypeptide chains

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654864

Molecular modeling study of tubulosine and other related ipecac alkaloids

5 September 2018

1 reference

12 December 2020

Enzymic and immunochemical properties of lysozyme. Evaluation of several amino group reversible blocking reagents

1 reference

12 December 2020

Phase I-II evaluation of emetine (NSC-33669) in the treatment of epidermoid bronchogenic carcinoma

1 reference

12 December 2020

A Mild and Simple Method for the Preparation of Isocyanates from Aliphatic Amines Using Trichloromethyl Chloroformate. Synthesis of an Isocyanate Containing an Activated Disulfide

1 reference

12 December 2020

Treatment of amoebiasis

1 reference

12 December 2020

Experience with emetine hydrochloride (NSC 33669) as an antitumor agent

1 reference

12 December 2020

Mitochondrial protein synthesis: inhibition by emetine hydrochloride

1 reference

12 December 2020

A phase I study of emetine hydrochloride (NSC 33669) in solid tumors.

1 reference

12 December 2020

Cis-aconityl spacer between daunomycin and macromolecular carriers: A model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate

1 reference

12 December 2020

Treatment of advanced gastrointestinal cancer with ememtine (NSC-33669)

1 reference

12 December 2020

Phase II study of emetine (NSC-33669) in the treatment of solid tumors

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM300426Q

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22867001%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22867001%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

22867001

1 reference