(Q36850321)

English

Microsomal triglyceride transfer protein inhibition induces endoplasmic reticulum stress and increases gene transcription via Ire1α/cJun to enhance plasma ALT/AST

scientific article published on 26 March 2013

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scholarly article

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27 February 2020

Microsomal triglyceride transfer protein inhibition induces endoplasmic reticulum stress and increases gene transcription via Ire1α/cJun to enhance plasma ALT/AST (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23532846%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

endoplasmic reticulum

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inferred from title

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27 February 2020

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27 February 2020

author name string

Joby Josekutty

1

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27 February 2020

Kenji Kohno

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27 February 2020

M Mahmood Hussain

5

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27 February 2020

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26 March 2013

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27 February 2020

Journal of Biological Chemistry

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27 February 2020

288

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27 February 2020

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27 February 2020

14372-14383

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27 February 2020

IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis

1 reference

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Multiple functions of microsomal triglyceride transfer protein

1 reference

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1 reference

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Intersection of the unfolded protein response and hepatic lipid metabolism

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Microsomal triglyceride transfer protein enhances cellular cholesteryl esterification by relieving product inhibition.

1 reference

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Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia

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Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways

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29 September 2017

Microsomal triglyceride transfer protein (MTP) inhibitors: discovery of clinically active inhibitors using high-throughput screening and parallel synthesis paradigms.

1 reference

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29 September 2017

A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors

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Evaluation of abnormal liver-enzyme results in asymptomatic patients

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Lovastatin: a new cholesterol-lowering agent

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Clinical use of serum enzymes in liver disease

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Identifiers

10.1074/JBC.M113.459602

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23532846%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

release_i26wzd22mfdm7lkoez5ktaahju

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27 February 2020

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27 February 2020

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