(Q36852276)

16 August 2017

title

PRO_SELECT: combining structure-based drug design and combinatorial chemistry for rapid lead discovery. 1. Technology (English)

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16 August 2017

Murray CW

1

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16 August 2017

Clark DE

2

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16 August 2017

Auton TR

3

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16 August 2017

Firth MA

4

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16 August 2017

Li J

5

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16 August 2017

Sykes RA

6

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16 August 2017

Waszkowycz B

7

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16 August 2017

Westhead DR

8

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16 August 2017

Young SC

9

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16 August 2017

publication date

1 March 1997

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Journal of Computer - Aided Molecular Design

16 August 2017

published in

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16 August 2017

volume

11

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16 August 2017

issue

2

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16 August 2017

page(s)

193-207

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Complex synthetic chemical libraries indexed with molecular tags

16 August 2017

cites work

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12 December 2020

Protein structure--based drug design

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12 December 2020

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Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library

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12 December 2020

Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine

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12 December 2020

PRO_LIGAND: an approach to de novo molecular design. 4. Application to the design of peptides

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12 December 2020

Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries

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12 December 2020

Thrombolysis in acute myocardial infarction

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12 December 2020

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12 December 2020

PRO_LIGAND: an approach to de novo molecular design. 6. Flexible fitting in the design of peptides

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12 December 2020

Rational modification of human synovial fluid phospholipase A2 inhibitors

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12 December 2020

PRO_LIGAND: an approach to de novo molecular design. 2. Design of novel molecules from molecular field analysis (MFA) models and pharmacophores.

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12 December 2020

The development of a simple empirical scoring function to estimate the binding constant for a protein-ligand complex of known three-dimensional structure

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12 December 2020

The computer program LUDI: a new method for the de novo design of enzyme inhibitors

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12 December 2020

"Diversomers": an approach to nonpeptide, nonoligomeric chemical diversity

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12 December 2020

Discovery of a novel tetrahydroacridine acetylcholinesterase inhibitor through an indexed combinatorial library

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12 December 2020

Application of the three-dimensional structures of protein target molecules in structure-based drug design

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12 December 2020

On the use of LUDI to search the Fine Chemicals Directory for ligands of proteins of known three-dimensional structure

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12 December 2020

Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors

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12 December 2020

De novo design of enzyme inhibitors by Monte Carlo ligand generation

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12 December 2020

Synthesis and Applications of Small Molecule Libraries

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12 December 2020

Use of peptide combinatorial libraries in drug design: the identification of a potent serotonin reuptake inhibitor derived from a tripeptide cassette library

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12 December 2020

Structure-based drug design

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

New promise in combinatorial chemistry: synthesis, characterization, and screening of small-molecule libraries in solution

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12 December 2020

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12 December 2020

PRO-LIGAND: an approach to de novo molecular design. 3. A genetic algorithm for structure refinement.

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12 December 2020

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12 December 2020

The coagulation cascade: initiation, maintenance, and regulation

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12 December 2020

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12 December 2020

Automated site-directed drug design: the formation of molecular templates in primary structure generation

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

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12 December 2020

Structure-based drug design: progress, results and challenges

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12 December 2020

Receptor surface models. 1. Definition and construction

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12 December 2020

The use of composite crystal-field environments in molecular recognition and the de novo design of protein ligands

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12 December 2020

Synthetic chemical diversity: solid phase synthesis of libraries of C2 symmetric inhibitors of HIV protease containing diamino diol and diamino alcohol cores

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12 December 2020

Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions

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12 December 2020

The NEWLEAD program: a new method for the design of candidate structures from pharmacophoric hypotheses.

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12 December 2020

Computational methods to predict binding free energy in ligand-receptor complexes

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12 December 2020

FOUNDATION: a program to retrieve all possible structures containing a user-defined minimum number of matching query elements from three-dimensional databases

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12 December 2020

Identifiers

DOI

10.1023/A:1008094712424

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journals/jcamd/MurrayCAFLSWWY97

16 August 2017

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

1040044452

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