(Q36853766)

16 August 2017

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title

Clinical relevance of sperm DNA damage in assisted reproduction (English)

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16 August 2017

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Nicoletta Tarozzi

1

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16 August 2017

Davide Bizzaro

series ordinal

2

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16 August 2017

Carlo Flamigni

series ordinal

3

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16 August 2017

Andrea Borini

series ordinal

4

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16 August 2017

publication date

1 June 2007

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16 August 2017

number of pages

12

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Reproductive BioMedicine Online

inferred from page(s)

published in

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16 August 2017

volume

14

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16 August 2017

issue

6

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16 August 2017

page(s)

746-757

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Role of sperm chromatin abnormalities and DNA damage in male infertility

16 August 2017

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7 January 2021

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7 January 2021

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7 January 2021

Relationships between biochemical markers for residual sperm cytoplasm, reactive oxygen species generation, and the presence of leukocytes and precursor germ cells in human sperm suspensions

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7 January 2021

Susceptibility of human sperm to in situ DNA denaturation is strongly correlated with DNA strand breaks identified by single-cell electrophoresis.

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7 January 2021

Analysis of DNA fragmentation, plasma membrane translocation of phosphatidylserine and oxidative stress in human spermatozoa

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7 January 2021

Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection

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7 January 2021

Real-time fine morphology of motile human sperm cells is associated with IVF-ICSI outcome

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7 January 2021

Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique

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7 January 2021

The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm.

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7 January 2021

Effect of deoxyribonucleic acid protamination on fluorochrome staining and in situ nick-translation of murine and human mature spermatozoa

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7 January 2021

Apoptosis precedes detachment of germ cells from the seminiferous epithelium after hormone suppression by short-term oestradiol treatment of rats

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7 January 2021

Sperm DNA fragmentation: paternal effect on early post-implantation embryo development in ART

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7 January 2021

Human gene expression first occurs between the four- and eight-cell stages of preimplantation development

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7 January 2021

The predictive value of sperm chromatin structure assay (SCSA) parameters for the outcome of intrauterine insemination, IVF and ICSI.

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7 January 2021

Sperm DNA fragmentation is increased in couples with unexplained recurrent pregnancy loss

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7 January 2021

LDH and LDH-X activity in sperm from normospermic and oligozoospermic men

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7 January 2021

A simple comet assay for archived sperm correlates DNA fragmentation to reduced hyperactivation and penetration of zona-free hamster oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

The comet assay: what can it really tell us?

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

The clinical value of sperm nuclear DNA assessment

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Assessment of DNA integrity and morphology of ejaculated spermatozoa from fertile and infertile men before and after cryopreservation

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Differences in nuclear DNA fragmentation and mitochondrial integrity of semen and prepared human spermatozoa

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Sperm DNA quality predicts intrauterine insemination outcome: a prospective cohort study

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Sperm chromatin structure assay is useful for fertility assessment

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Meta-analysis of sperm DNA fragmentation using the sperm chromatin structure assay

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques

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7 January 2021

Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic

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7 January 2021

Morphogenetic factors influencing the shape of the sperm head

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

The comet assay: a comprehensive review

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Expression of gp20, a human sperm antigen of epididymal origin, is reduced in spermatozoa from subfertile men

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: analogy to apoptosis of somatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

ICSI in cases of sperm DNA damage: beneficial effect of oral antioxidant treatment

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozoa

1 reference

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7 January 2021

Comparison of reactive oxygen species concentration in seminal plasma and semen parameters in partners of pregnant and non-pregnant patients after IVF/ICSI

1 reference

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7 January 2021

The effect of chromatin condensation (aniline blue staining) and morphology (strict criteria) of human spermatozoa on fertilization, cleavage and pregnancy rates in an intracytoplasmic sperm injection programme

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

High-magnification ICSI overcomes paternal effect resistant to conventional ICSI.

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Influence of deoxyribonucleic acid damage on fertilization and pregnancy

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7 January 2021

DNA fragmentation of spermatozoa and assisted reproduction technology

1 reference

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7 January 2021

The role of DNA strand breaks in human spermatozoa used for IVF and ICSI.

1 reference

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7 January 2021

Sperm DNA fragmentation negatively correlates with velocity and fertilization rates but might not affect pregnancy rates

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

The morphology and kinetics of spermatogonial degeneration in normal adult rats: An analysis using a simplified classification of the germinal epithelium

1 reference

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7 January 2021

Selected genetic factors associated with male infertility.

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Investigation of the association between the presence of cytoplasmic residues on the human sperm midpiece and defective sperm function

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

New insights into the origin, structure and role of CD52: a major component of the mammalian sperm glycocalyx

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

On the nature and origin of DNA strand breaks in elongating spermatids

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Sperm chromatin structure assay parameters as predictors of failed pregnancy following assisted reproductive techniques

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Density gradient centrifugation and glass wool filtration of semen remove spermatozoa with damaged chromatin structure

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Relationship between the outcomes of assisted reproductive techniques and sperm DNA fragmentation as measured by the sperm chromatin structure assay

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

An algorithm to predict pregnancy in assisted reproduction.

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Sperm deoxyribonucleic acid fragmentation is increased in poor-quality semen samples and correlates with failed fertilization in intracytoplasmic sperm injection

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Presence of endogenous nicks in DNA of ejaculated human spermatozoa and its relationship to chromomycin A3 accessibility

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Transient DNA strand breaks during mouse and human spermiogenesis new insights in stage specificity and link to chromatin remodeling

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Paternal and maternal factors in preimplantation embryogenesis: interaction with the biochemical environment

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Sperm selection capacity of the human zona pellucida.

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Effect of sperm DNA damage and sperm protamine deficiency on fertilization and embryo development post-ICSI.

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Assisted reproduction in the azoospermic couple

1 reference

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7 January 2021

Differences in mitochondrial and nuclear DNA status of high-density and low-density sperm fractions after density centrifugation preparation.

1 reference

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7 January 2021

The comet assay: a new method to examine heterogeneity associated with solid tumors

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7 January 2021

How do male germ cells handle DNA damage?

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Integrating new tests of sperm genetic integrity into semen analysis: breakout group discussion.

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Isolation and characterization of a rat cDNA clone encoding a secreted superoxide dismutase reveals the epididymis to be a major site of its expression

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

The relevance of spontaneous- and chemically-induced alterations in testicular germ cell apoptosis to toxicology.

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Antioxidant treatment of patients with asthenozoospermia or moderate oligoasthenozoospermia with high-dose vitamin C and vitamin E: a randomized, placebo-controlled, double-blind study

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Bax-dependent spermatogonia apoptosis is required for testicular development and spermatogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

The use of two density gradient centrifugation techniques and the swim-up method to separate spermatozoa with chromatin and nuclear DNA anomalies

1 reference

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7 January 2021

Origin of DNA damage in ejaculated human spermatozoa.

1 reference

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7 January 2021

Abnormal sperm parameters in humans are indicative of an abortive apoptotic mechanism linked to the Fas-mediated pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Sperm selection methods for intracytoplasmic sperm injection (ICSI) in andrological patients

1 reference

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7 January 2021

Spermatozoal nuclear determinants of reproductive outcome: implications for ART.

1 reference

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7 January 2021

Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization

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7 January 2021

Longitudinal study of sperm DNA fragmentation as measured by terminal uridine nick end-labelling assay

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7 January 2021

Sperm DNA fragmentation: threshold value in male fertility

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7 January 2021

Abundant alkali-sensitive sites in DNA of human and mouse sperm

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7 January 2021

A simple technique for quantitation of low levels of DNA damage in individual cells

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Influence of paternal age on the risk of spontaneous abortion

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

DNA nicks and increased sensitivity of DNA to fluorescence in situ end labeling during functional spermiogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Total antioxidant capacity of human seminal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

The significance of sperm nuclear DNA strand breaks on reproductive outcome

1 reference

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7 January 2021

The applicability of the flow cytometric sperm chromatin structure assay in epidemiological studies. Asclepios

1 reference

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7 January 2021

A comparison of DNA damage in testicular and proximal epididymal spermatozoa in obstructive azoospermia

1 reference

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7 January 2021

Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro

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https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Paternal effects on cell division in the human preimplantation embryo

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7 January 2021

Sperm nuclear DNA damage: update on the mechanism, diagnosis and treatment

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7 January 2021

Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation

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7 January 2021

Interrelationships between seminal parameters and sperm nuclear DNA damage before and after density gradient centrifugation: implications for assisted conception

1 reference

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7 January 2021

Embryo quality and IVF treatment outcomes may correlate with different sperm comet assay parameters

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Iatrogenic DNA damage induced in human spermatozoa during sperm preparation: protective significance of seminal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Incidence of aneuploid spermatozoa from subfertile men: selected with motility versus hemizona-bound

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Tyrosine as important contributor to the antioxidant capacity of seminal plasma

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7 January 2021

No increase in sperm DNA damage and seminal oxidative stress in patients with idiopathic infertility

1 reference

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7 January 2021

Sperm chromatin structure assay (SCSA) parameters are related to fertilization, blastocyst development, and ongoing pregnancy in in vitro fertilization and intracytoplasmic sperm injection cycles

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

The role of DNA topoisomerases in recombination and genome stability: a double-edged sword?

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7 January 2021

Autonomous cell death of mouse male germ cells during fetal and postnatal period.

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

DNA packaging and organization in mammalian spermatozoa: comparison with somatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Expression of the pem homeobox gene in Sertoli cells increases the frequency of adjacent germ cells with deoxyribonucleic acid strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile men

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

Influence of semen processing technique on human sperm DNA integrity

1 reference

https://api.crossref.org/works/10.1016%2FS1472-6483%2810%2960678-5

7 January 2021

10.1016/S1472-6483(10)60678-5

Identifiers

DOI

1 reference

16 August 2017

1 reference