(Q36866334)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

review article

1 reference

title

Fat targets for skeletal health (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Masanobu Kawai

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Clifford J Rosen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

26 May 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Rheumatology

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

365-372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrrheum.2009.102

29 January 2020

exact match

0 references

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29 September 2017

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The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity

29 September 2017

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29 September 2017

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29 September 2017

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Plasma osteocalcin is inversely related to fat mass and plasma glucose in elderly Swedish men

29 September 2017

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The influence of ghrelin, adiponectin, and leptin on bone mineral density in healthy postmenopausal women

29 September 2017

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Strain-specific effects of rosiglitazone on bone mass, body composition, and serum insulin-like growth factor-I

29 September 2017

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Mice lacking beta-adrenergic receptors have increased bone mass but are not protected from deleterious skeletal effects of ovariectomy.

29 September 2017

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A bone structural basis for fracture risk in diabetes

29 September 2017

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TZDs and Bone: A Review of the Recent Clinical Evidence

29 September 2017

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Adrenergic control of bone remodeling and its implications for the treatment of osteoporosis.

29 September 2017

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Use of thiazolidinediones and fracture risk

29 September 2017

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Caloric restriction decreases cortical bone mass but spares trabecular bone in the mouse skeleton: implications for the regulation of bone mass by body weight.

29 September 2017

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Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice

29 September 2017

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Molecular bases of the sympathetic regulation of bone mass

29 September 2017

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Association of leptin receptor polymorphisms Lys109Arg and Gln223Arg with serum leptin profile and bone mineral density in Korean women

29 September 2017

1 reference

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Rosiglitazone-associated fractures in type 2 diabetes: an Analysis from A Diabetes Outcome Progression Trial (ADOPT).

29 September 2017

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Bone remodeling, energy metabolism, and the molecular clock

29 September 2017

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PPAR-gamma regulates osteoclastogenesis in mice

29 September 2017

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Leptin and the sympathetic connection of fat to bone

29 September 2017

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Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice

29 September 2017

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Bone mass in prepubertal boys is associated with a Gln223Arg amino acid substitution in the leptin receptor

29 September 2017

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Endocrine regulation of energy metabolism by the skeleton

29 September 2017

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The new field of neuroskeletal biology

29 September 2017

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Opposite effects of leptin on bone metabolism: a dose-dependent balance related to energy intake and insulin-like growth factor-I pathway

29 September 2017

1 reference

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The peroxisome proliferator-activated receptor-gamma agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial

29 September 2017

1 reference

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Influence of insulin-like growth factor-1 and leptin on bone mineral content in healthy premenopausal women.

29 September 2017

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Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade

29 September 2017

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Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial

29 September 2017

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Bone abnormalities in adolescent leptin-deficient mice

29 September 2017

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Leptin predicts BMD and bone resorption in older women but not older men: the Rancho Bernardo study

29 September 2017

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Thiazolidinedione use and bone loss in older diabetic adults

29 September 2017

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Playing with bone and fat.

29 September 2017

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Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat.

29 September 2017

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Neuronal signaling and the regulation of bone remodeling

29 September 2017

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Leptin regulates chondrocyte differentiation and matrix maturation during endochondral ossification

29 September 2017

1 reference

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Leptin regulation of bone resorption by the sympathetic nervous system and CART

29 September 2017

1 reference

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29 September 2017

Oral Antidiabetic Agents

1 reference

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Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology

29 September 2017

1 reference

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Enhanced bone formation in lipodystrophic PPARgamma(hyp/hyp) mice relocates haematopoiesis to the spleen

29 September 2017

1 reference

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29 September 2017

1 reference

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Leptin, bone mass, and the thrifty phenotype

29 September 2017

1 reference

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Recombinant human leptin in women with hypothalamic amenorrhea.

29 September 2017

1 reference

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Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

29 September 2017

1 reference

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Leptin deficiency produces contrasting phenotypes in bones of the limb and spine

29 September 2017

1 reference

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Serum leptin level is a regulator of bone mass

29 September 2017

1 reference

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Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm

29 September 2017

1 reference

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Leptin regulates bone formation via the sympathetic nervous system

29 September 2017

1 reference

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The epidemiology of corticosteroid-induced osteoporosis: a meta-analysis

29 September 2017

1 reference

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Serum leptin level is a predictor of bone mineral density in postmenopausal women.

29 September 2017

1 reference

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Association between serum leptin concentrations and bone mineral density, and biochemical markers of bone turnover in adult men.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Plasma leptin concentrations are associated with bone mineral density and the presence of vertebral fractures in postmenopausal women

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Leptin is a potent stimulator of bone growth in ob/ob mice

29 September 2017

1 reference

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Pluripotential marrow cells produce adipocytes when transplanted into steroid-treated mice

29 September 2017

1 reference

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Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2

29 September 2017

1 reference

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Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression

29 September 2017

1 reference

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Biochemical markers of bone turnover for the clinical investigation of osteoporosis

29 September 2017

1 reference

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Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

29 September 2017

1 reference

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Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Hypoxic adipocytes pattern early heterotopic bone formation.

29 September 2017

1 reference

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Selected contribution: Bone adaptation with aging and long-term caloric restriction in Fischer 344 x Brown-Norway F1-hybrid rats.

27 June 2018

1 reference

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Serotonin rising--the bone, brain, bowel connection

27 June 2018

1 reference

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Beta-adrenergic blockade and leptin replacement effectively mitigate disuse bone loss.

4 September 2018

1 reference

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Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Bone mineral density and bone turnover in relation to serum leptin, alpha-ketoglutarate and sex steroids in overweight and obese postmenopausal women.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Life-long caloric restriction reveals biphasic and dimorphic effects on bone metabolism in rodents.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Leptin receptor genotype at Gln223Arg is associated with body composition, BMD, and vertebral fracture in postmenopausal Danish women.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Leptin is a negative independent predictor of areal BMD and cortical bone size in young adult Swedish men.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Are serum leptin and the Gln223Arg polymorphism of the leptin receptor determinants of bone homeostasis in elderly men?

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Effects of a beta-blocker on bone turnover in normal postmenopausal women: a randomized controlled trial

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Leptin modulates both resorption and formation while preventing disuse-induced bone loss in tail-suspended female rats.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Dietary restriction does not adversely affect bone geometry and mechanics in rapidly growing male wistar rats.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong Osteoporosis Study

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Body composition and bone measurements in intra-uterine growth retarded and early postnatally undernourished male and female rats at the age of 6 months: comparison with puberty.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Leptin reverses the inhibitory effect of caloric restriction on longitudinal growth.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Mechanism and implications of brown adipose tissue proliferation in rats and monkeys treated with the thiazolidinedione darglitazone, a potent peroxisome proliferator-activated receptor-gamma agonist

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Estrogen receptor alpha gene polymorphisms Pvu II and Xba I influence association between leptin receptor gene polymorphism (Gln223Arg) and bone mineral density in young men.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Troglitazone treatment increases bone marrow adipose tissue volume but does not affect trabecular bone volume in mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

β-blocker use and risk of fractures in men and women from the general population: the MONICA/KORA Augsburg cohort study

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Leptin Inhibits Osteoclast Generation

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661210

Evidence for a dense and intimate innervation of the bone tissue, including glutamate-containing fibers

4 December 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Osteopenia in mice with genetic diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Growth deceleration and bone metabolism in nutritional dwarfing rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Bone status in an animal model of chronic sub-optimal nutrition: a morphometric, densitometric and mechanical study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

The effects of caloric restriction on skeletal growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Protective effect of beta blockers in postmenopausal women: influence on fractures, bone density, micro and macroarchitecture

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Surface-specific effects of a PPARgamma agonist, darglitazone, on bone in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

The DREAM trial – Authors' reply

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Risk of Fracture in Women with Type 2 Diabetes: the Women’s Health Initiative Observational Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Endocrine abnormalities in anorexia nervosa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.102

What’s in a Name? In Search of Leptin’s Physiologic Role1

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19468288

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phenotypic effects of calorie restriction and insulin-like growth factor-1 treatment on body composition and bone mineral density of C57BL/6 mice: implications for cancer prevention

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19468288

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The effects of age and dietary restriction without nutritional supplementation on whole bone structural properties in C57BL/6J mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19468288

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRRHEUM.2009.102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19468288%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference