(Q36867020)

16 August 2017

The open structure of a multi-drug-resistant HIV-1 protease is stabilized by crystal packing contacts (English)

1 reference

16 August 2017

multiple drug resistance

1 reference

Melinda Layten

1

1 reference

16 August 2017

Viktor Hornak

series ordinal

2

1 reference

16 August 2017

Carlos Simmerling

series ordinal

3

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 October 2006

1 reference

Journal of the American Chemical Society

16 August 2017

1 reference

16 August 2017

128

1 reference

16 August 2017

41

1 reference

16 August 2017

13360-13361

1 reference

The survival benefits of AIDS treatment in the United States

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

HIV-1 protease flaps spontaneously close to the correct structure in simulations following manual placement of an inhibitor into the open state

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

HIV-1 protease flaps spontaneously open and reclose in molecular dynamics simulations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

HIV-1 protease molecular dynamics of a wild-type and of the V82F/I84V mutant: possible contributions to drug resistance and a potential new target site for drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

Rapid structural fluctuations of the free HIV protease flaps in solution: relationship to crystal structures and comparison with predictions of dynamics calculations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

VMD: visual molecular dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

The three-dimensional structure of the aspartyl protease from the HIV-1 isolate BRU

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

"Wide-open" 1.3 A structure of a multidrug-resistant HIV-1 protease as a drug target

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

Restrained molecular dynamics simulations of HIV-1 protease: the first step in validating a new target for drug design

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

HIVdb: a database of the structures of human immunodeficiency virus protease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532084

4 September 2018

Identifiers

DOI

10.1021/JA065133K

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

17031940

1 reference