(Q36867191)

16 August 2017

Structure-based design and combinatorial chemistry yield low nanomolar inhibitors of cathepsin D. (English)

1 reference

16 August 2017

Kick EK

1

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16 August 2017

Roe DC

2

1 reference

16 August 2017

Skillman AG

3

1 reference

16 August 2017

Liu G

4

1 reference

16 August 2017

Ewing TJ

5

1 reference

16 August 2017

Sun Y

6

1 reference

16 August 2017

Kuntz ID

7

1 reference

16 August 2017

Ellman JA

8

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16 August 2017

1 April 1997

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16 August 2017

Chemistry and Biology

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16 August 2017

4

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16 August 2017

4

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16 August 2017

297-307

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Structure-based strategies for drug design and discovery

16 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Synthesis and Applications of Small Molecule Libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Molecular modeling software and methods for medicinal chemistry

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Measuring diversity: experimental design of combinatorial libraries for drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Cathepsin D and breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Peptidomimetics derived from natural products

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

The selectivity of statine-based inhibitors against various human aspartic proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Inhibition of cathepsin D by substrate analogues containing statine and by analogues of pepstatin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Expedient method for the solid-phase synthesis of aspartic acid protease inhibitors directed toward the generation of libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Automated site-directed drug design using molecular lattices

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

BUILDER v.2: improving the chemistry of a de novo design strategy

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Synthetic approaches to continuous assays of retroviral proteases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Automated docking with grid-based energy evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

Tight-binding inhibitors-II. Non-steady state nature of inhibition of milk xanthine oxidase by allopurinol and alloxanthine and of human erythrocytic adenosine deaminase by coformycin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990073-9

7 January 2021

10.1016/S1074-5521(97)90073-9

Identifiers

DOI

1 reference

16 August 2017

1 reference