(Q36869340)

16 August 2017

1 reference

title

Structure, biochemistry and biology of hepoxilins: an update (English)

1 reference

16 August 2017

1 reference

ChEBI release 2020-05-28

ChEBI ID

132809

(8S)-hepoxilin A3(1-)

1 reference

ChEBI release 2020-05-28

Santosh Nigam

1

1 reference

16 August 2017

Maria-Patapia Zafiriou

2

1 reference

16 August 2017

Rupal Deva

3

1 reference

16 August 2017

Roberto Ciccoli

4

1 reference

16 August 2017

Renate Roux-Van der Merwe

5

1 reference

16 August 2017

language of work or name

English

0 references

publication date

2 July 2007

1 reference

16 August 2017

1 reference

16 August 2017

volume

274

1 reference

16 August 2017

issue

14

1 reference

16 August 2017

page(s)

3503-3512

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

16 August 2017

1 reference

Hepoxilin A3 induces changes in cytosolic calcium, intracellular pH and membrane potential in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Biosynthesis of hepoxilins: evidence for the presence of a hepoxilin synthase activity in rat insulinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Resolution by DEAE-cellulose chromatography of the enzymatic steps in the transformation of arachidonic acid into 8, 11, 12- and 10, 11, 12-trihydroxy-eicosatrienoic acid by the rat lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Hepoxilin, a new family of insulin secretagogues formed by intact rat pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Endogenous release of hepoxilin A3 from isolated perifused pancreatic islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Hepoxilin A3 blocks the release of norepinephrine from rat hippocampal slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Hepoxilin A3 (HxA3) is formed by the rat aorta and is metabolized into HxA3-C, a glutathione conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

21 January 2018

Hepoxilin A3 synthase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

The rat leukocyte-type 12-lipoxygenase exhibits an intrinsic hepoxilin A3 synthase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Shape and specificity in mammalian 15-lipoxygenase active site. The functional interplay of sequence determinants for the reaction specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

A primary determinant for lipoxygenase positional specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Site-directed mutagenesis studies on the iron-binding domain and the determinant for the substrate oxygenation site of porcine leukocyte arachidonate 12-lipoxygenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Rat 12-lipoxygenase: mutations of amino acids implicated in the positional specificity of 15- and 12-lipoxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

The formation of threo-11-hydroxy-trans-12: 13-epoxy-9-cis-octadecenoic acid by enzymic isomerisation of 13-L-hydroperoxy-9-cis, 11-transoctadecadienoic acid by soybean lipoxygenase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Isolation of a new lipoxygenase metabolite of arachidonic acid, 8,11,12-trihydroxy-5,9,14-eicosatrienoic acid from human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Lipoxin and aspirin-triggered 15-epi-lipoxin cellular interactions anti-inflammatory lipid mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Lipoxin synthase activity of human platelet 12-lipoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Kinetics of inhibition of leukocyte 12-lipoxygenase by the isoform-specific inhibitor 4-(2-oxapentadeca-4-yne)phenylpropanoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

The selenoenzyme phospholipid hydroperoxide glutathione peroxidase controls the activity of the 15-lipoxygenase with complex substrates and preserves the specificity of the oxygenation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Purification of a cytosolic enzyme from human liver with phospholipid hydroperoxide glutathione peroxidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Hepoxilin signaling in intact human neutrophils: biphasic elevation of intracellular calcium by unesterified hepoxilin A3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Biological actions of the free acid of hepoxilin A3 on human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Receptor-mediated action of hepoxilin A3 releases diacylglycerol and arachidonic acid from human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Products of heme-catalyzed transformation of the arachidonate derivative 12-HPETE open S-type K+ channels in Aplysia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

A glutathione conjugate of hepoxilin A3: formation and action in the rat central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Actions of arachidonic acid and hepoxilin A3 on mammalian hippocampal CA1 neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

PBT-3, a hepoxilin stable analog, causes long term inhibition of growth of K562 solid tumours in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

A new family of thromboxane receptor antagonists with secondary thromboxane synthase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

COX-2: a molecular target for colorectal cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

NSAIDs and chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Heat shock protein 72 expression in chondrosarcoma correlates with differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Hepoxilin-evoked intracellular reorganization of calcium in human neutrophils: a confocal microscopy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Hepoxilin A3-specific binding in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Hepoxilin analogs, potential new therapeutics in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non-stressed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Orchestrating the unfolded protein response in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Transcriptional and translational control in the Mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Tripartite management of unfolded proteins in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Exaggerated spontaneous release of platelet-derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Allergic lung responses are increased in prostaglandin H synthase-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Protection from pulmonary fibrosis in leukotriene-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

Hepoxilin analogs inhibit bleomycin-induced pulmonary fibrosis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05910.X

10.1111/J.1742-4658.2007.05910.X

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference