(Q36870574)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18515784%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy (English)

1 reference

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8 January 2020

1 reference

1 reference

Konstantinos Drosatos

4

1 reference

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8 January 2020

E. Dale Abel

10

1 reference

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8 January 2020

author name string

Tae-Sik Park

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18515784%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Yunying Hu

2

1 reference

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8 January 2020

Hye-Lim Noh

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18515784%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Kazue Okajima

5

1 reference

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8 January 2020

Jonathan Buchanan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18515784%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Joseph Tuinei

7

1 reference

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8 January 2020

Shunichi Homma

8

1 reference

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8 January 2020

Xian-Cheng Jiang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18515784%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Ira J Goldberg

11

1 reference

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8 January 2020

publication date

30 May 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18515784%20AND%20SRC:MED&resulttype=core&format=json

Journal of Lipid Research

8 January 2020

published in

1 reference

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8 January 2020

volume

49

1 reference

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8 January 2020

issue

10

1 reference

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8 January 2020

page(s)

2101-2112

1 reference

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Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice

8 January 2020

cites work

1 reference

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Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

29 September 2017

1 reference

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TLR4 links innate immunity and fatty acid-induced insulin resistance

29 September 2017

1 reference

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The prevention and treatment of metabolic syndrome and high-risk obesity

29 September 2017

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Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Absorption and lipoprotein transport of sphingomyelin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice

29 September 2017

1 reference

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Novel cell lines derived from adult human ventricular cardiomyocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

A simple method for the isolation and purification of total lipides from animal tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Mechanisms of lipoapoptosis: implications for human heart disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

A novel mouse model of lipotoxic cardiomyopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Glucose metabolism in perfused mouse hearts overexpressing human GLUT-4 glucose transporter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Lipotoxic heart disease in obese rats: implications for human obesity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Rapid, specific, and sensitive measurements of plasma sphingomyelin and phosphatidylcholine

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Glycogen depletion in intrafusal fibres in rats during short-duration high-intensity treadmill running.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Altered hepatic and muscle substrate utilization provoked by GLUT4 ablation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Akt signaling pathway in pacing-induced heart failure

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscle.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Anesthetic inhibition in ischemic and nonischemic murine heart: comparison with conscious echocardiographic approach

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533410

Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.M800147-JLR200

Differential Activation of Signal Transduction Pathways in Human Hearts With Hypertrophy Versus Advanced Heart Failure

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.M800147-JLR200

CD36 Deficiency Rescues Lipotoxic Cardiomyopathy

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.M800147-JLR200

Suppression of murine cardiac allograft arteriopathy by long-term blockade of CD40-CD154 interactions

21 January 2018

1 reference

12 December 2020

Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia

1 reference

12 December 2020

Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakizaki (GK), obese/aged, and obese/Zucker rats. A mechanism for inhibiting glycogen synthesis

1 reference

12 December 2020

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

12 December 2020

Sodium palmitate induces partial mitochondrial uncoupling and reactive oxygen species in rat pancreatic islets in vitro

1 reference

12 December 2020

Glucose and fatty acid metabolism in the isolated working mouse heart

1 reference

12 December 2020

Akt1 is required for physiological cardiac growth

1 reference

12 December 2020

Cardiac steatosis in diabetes mellitus: a 1H-magnetic resonance spectroscopy study

1 reference

12 December 2020

Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice

1 reference

12 December 2020

Quantitative determination of ceramide using diglyceride kinase

1 reference

12 December 2020

10.1194/JLR.M800147-JLR200

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18515784%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18515784%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference