(Q36871645)

English

Asp330 and Tyr331 in the C-terminal cysteine-rich region of the luteinizing hormone receptor are key residues in hormone-induced receptor activation

scientific article published on 19 July 2008

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Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Asp330 and Tyr331 in the C-terminal cysteine-rich region of the luteinizing hormone receptor are key residues in hormone-induced receptor activation (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Martijn Bruysters

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Miriam Verhoef-Post

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Axel P N Themmen

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

0 references

publication date

19 July 2008

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

283

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

38

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

25821-25828

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

The thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction

1 reference

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29 September 2017

Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody

1 reference

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29 September 2017

Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns

1 reference

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29 September 2017

A low molecular weight agonist signals by binding to the transmembrane domain of thyroid-stimulating hormone receptor (TSHR) and luteinizing hormone/chorionic gonadotropin receptor (LHCGR).

1 reference

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29 September 2017

Structural analysis of leucine-rich-repeat variants in proteins associated with human diseases

1 reference

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29 September 2017

An update of the pathophysiology of human gonadotrophin subunit and receptor gene mutations and polymorphisms

1 reference

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Structure of human follicle-stimulating hormone in complex with its receptor

1 reference

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29 September 2017

A molecular dissection of the glycoprotein hormone receptors.

1 reference

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Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins

1 reference

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29 September 2017

Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain

1 reference

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29 September 2017

International Union of Pharmacology. XXVIII. Proteinase-activated receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

The leucine-rich repeat as a protein recognition motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

Molecular basis of lutropin recognition by the mannose/GalNAc-4-SO4 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

The amino-terminal region of the luteinizing hormone/choriogonadotropin receptor contacts both subunits of human choriogonadotropin. I. Mutational analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

Requirement of cysteine residues in exons 1-6 of the extracellular domain of the luteinizing hormone receptor for gonadotropin binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

Pseudo-von Willebrand disease: a mutation in the platelet glycoprotein Ib alpha gene associated with a hyperactive surface receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

Proteins with leucine-rich repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

Mutation in the gene encoding the alpha chain of platelet glycoprotein Ib in platelet-type von Willebrand disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

A missense mutation in the second transmembrane segment of the luteinizing hormone receptor causes familial male-limited precocious puberty

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

29 September 2017

Significance of ectodomain cysteine boxes 2 and 3 for the activation mechanism of the thyroid-stimulating hormone receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

27 June 2018

Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533784

27 June 2018

Functional expression of the recombinant human FSH receptor

1 reference

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27 June 2018

Binding assay for thyrotropin receptor autoantibodies using the recombinant receptor protein

1 reference

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27 June 2018

The first orally active low molecular weight agonists for the LH receptor: thienopyr(im)idines with therapeutic potential for ovulation induction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804395200

21 January 2018

Development of isotopic and non-isotopic microwell based immunoassays for hCG using 125I and biotin labeled hCG.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804395200

21 January 2018

Absence of exon 10 of the human luteinizing hormone (LH) receptor impairs LH, but not human chorionic gonadotropin action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804395200

21 January 2018

Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues

1 reference

https://pubmed.ncbi.nlm.nih.gov/18641392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Male hypogonadism caused by homozygous deletion of exon 10 of the luteinizing hormone (LH) receptor: differential action of human chorionic gonadotropin and LH

1 reference

https://pubmed.ncbi.nlm.nih.gov/18641392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of an in vitro biologically active equine LH/CG without C-terminal peptide (CTP) and/or beta26-110 disulphide bridge

1 reference

https://pubmed.ncbi.nlm.nih.gov/18641392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/18641392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analyses of the extracellular domain of the full-length lutropin/choriogonadotropin receptor suggest leucine-rich repeats 1-6 are involved in hormone binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/18641392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Class B GPCRs: a hidden agonist within?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18641392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M804395200

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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