(Q36873023)

16 August 2017

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title

Synthetic library techniques: subjective (biased and generic) thoughts and views (English)

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16 August 2017

Krchnák V

1

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16 August 2017

Lebl M

series ordinal

2

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16 August 2017

publication date

1 May 1996

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16 August 2017

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16 August 2017

volume

1

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16 August 2017

issue

3

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16 August 2017

page(s)

193-216

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https://scigraph.springernature.com/pub.10.1007/bf01544958

16 August 2017

exact match

0 references

cites work

Complex synthetic chemical libraries indexed with molecular tags

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12 December 2020

Discovering peptide ligands using epitope libraries

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12 December 2020

Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library

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12 December 2020

A new type of synthetic peptide library for identifying ligand-binding activity

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12 December 2020

Multiple release of equimolar amounts of peptides from a polymeric carrier using orthogonal linkage-cleavage chemistry

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12 December 2020

The discovery of librium

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12 December 2020

Application of a dual color detection scheme in the screening of a random combinatorial peptide library

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12 December 2020

Evaluation of peptide libraries: an iterative strategy to analyze the reactivity of peptide mixtures with antibodies

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12 December 2020

One-bead-one-structure combinatorial libraries

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12 December 2020

Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries

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12 December 2020

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids

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The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library

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12 December 2020

General method for rapid synthesis of multicomponent peptide mixtures

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12 December 2020

The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid receptor ligands

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12 December 2020

An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library

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12 December 2020

Creation and functional screening of a multi-use peptide library

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12 December 2020

Carrier bound synthetic oligopeptides in ELISA test systems for distinction between HIV-1 and HIV-2 infection.

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12 December 2020

Carrier-bound synthetic peptides. Use as antigen in HIV-1 ELISA tests and in antiserum production

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12 December 2020

Liquid-phase combinatorial synthesis

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12 December 2020

A priori delineation of a peptide which mimics a discontinuous antigenic determinant

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12 December 2020

Effects of arginine vasopressin (AVP) infusions on circulating concentrations of platelet AVP, factor VIII: C and von Willebrand factor

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12 December 2020

Identifying substrate motifs of protein kinases by a random library approach

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12 December 2020

Pharmacology of N-[4-(4-morpholinylcarbonyl)benzoyl]-L-valyl-N- [3,3,4,4,4-pentafluoro-1-(1-methylethyl)-2-oxobutyl]-L-prolinamide (MDL 101,146): a potent orally active inhibitor of human neutrophil elastase

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12 December 2020

A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor

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12 December 2020

Peptide libraries: criteria and trends

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12 December 2020

Libraries of peptides and proteins displayed on filamentous phage

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12 December 2020

Random peptide libraries.

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12 December 2020

Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid

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12 December 2020

Light-directed, spatially addressable parallel chemical synthesis

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12 December 2020

Combinatorial technologies involving reiterative division/coupling/recombination: statistical considerations.

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12 December 2020

Detection of secondary amines on solid phase

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12 December 2020

Peptide-encoding for structure determination of nonsequenceable polymers within libraries synthesized and tested on solid-phase supports

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12 December 2020

The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures

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12 December 2020

Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides

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12 December 2020

A review of the utility of soluble peptide combinatorial libraries.

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12 December 2020

Library of libraries: approach to synthetic combinatorial library design and screening of "pharmacophore" motifs

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12 December 2020

Synthesis of combinatorial libraries with only one representation of each structure.

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12 December 2020

Six highly active mu-selective opioid peptides identified from two synthetic combinatorial libraries

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12 December 2020

Expedient method for the solid-phase synthesis of aspartic acid protease inhibitors directed toward the generation of libraries

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12 December 2020

Synthesis and Applications of Small Molecule Libraries

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12 December 2020

Generation and screening of an oligonucleotide-encoded synthetic peptide library

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12 December 2020

Studies directed toward the design of orally active renin inhibitors. 2. Development of the efficacious, bioavailable renin inhibitor (2S)-2-benzyl-3- [[(1-methylpiperazin-4-yl)sulfonyl]propionyl]-3-thiazol-4-yl-L-alanine amide of (2S,3R,4S)-2-amino

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12 December 2020

Peptoids: a modular approach to drug discovery.

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12 December 2020

Measuring diversity: experimental design of combinatorial libraries for drug discovery

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12 December 2020

A mass spectrometric solution to the address problem of combinatorial libraries

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12 December 2020

Discovery of biologically active peptides in random libraries: solution-phase testing after staged orthogonal release from resin beads

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12 December 2020

New promise in combinatorial chemistry: synthesis, characterization, and screening of small-molecule libraries in solution

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12 December 2020

Cyclic peptide template combinatorial libraries: synthesis and identification of chymotrypsin inhibitors

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12 December 2020

Electrospray mass spectrometry and tandem mass spectrometry of synthetic multicomponent peptide mixtures: determination of composition and purity

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12 December 2020

Screening of synthetic peptide libraries with radiolabeled acceptor molecules

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12 December 2020

Tagged versus untagged libraries: methods for the generation and screening of combinatorial chemical libraries

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12 December 2020

Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endoprotease specificity

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12 December 2020

Discovery of a peptide-based renin inhibitor with oral bioavailability and efficacy

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12 December 2020

A paradigm for drug discovery employing encoded combinatorial libraries

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12 December 2020

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

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12 December 2020

Adaptive walks with noisy fitness measurements.

1 reference

12 December 2020

Oral desmopressin in central diabetes insipidus

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12 December 2020

Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions

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12 December 2020

Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries

1 reference

12 December 2020

Studies directed toward the design of orally active renin inhibitors. 1. Some factors influencing the absorption of small peptides

1 reference

12 December 2020

Encoded combinatorial chemistry

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01544958

1 reference

16 August 2017

1 reference