(Q36875981)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27158244%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

title

Temozolomide promotes genomic and phenotypic changes in glioblastoma cells (English)

1 reference

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4 April 2020

0 references

1 reference

1 reference

10

1 reference

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4 April 2020

Aleksey Stepanenko

1

1 reference

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4 April 2020

Vladimir Baklaushev

5

1 reference

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4 April 2020

Kateryna Kotsarenko

8

1 reference

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4 April 2020

Stanislav Avdieiev

11

1 reference

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4 April 2020

author name string

Svitlana V Andreieva

2

1 reference

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4 April 2020

Kateryna V Korets

3

1 reference

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4 April 2020

Dmytro O Mykytenko

4

1 reference

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4 April 2020

Nataliya L Huleyuk

6

1 reference

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4 April 2020

Oksana A Kovalova

7

1 reference

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4 April 2020

Vladimir P Chekhonin

9

1 reference

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4 April 2020

Vladimir V Dmitrenko

12

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4 April 2020

publication date

5 May 2016

1 reference

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Cancer Cell International

4 April 2020

published in

1 reference

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4 April 2020

volume

16

1 reference

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4 April 2020

page(s)

36

1 reference

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https://scigraph.springernature.com/pub.10.1186/s12935-016-0311-8

4 April 2020

exact match

0 references

cites work

mTOR inhibitor temsirolimus and MEK1/2 inhibitor U0126 promote chromosomal instability and cell type-dependent phenotype changes of glioblastoma cells

1 reference

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Pitfalls of the MTT assay: Direct and off-target effects of inhibitors can result in over/underestimation of cell viability.

29 September 2017

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Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment

29 September 2017

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Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution

29 September 2017

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Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity

29 September 2017

1 reference

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The mTOR signaling pathway as a treatment target for intracranial neoplasms

29 September 2017

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ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents

29 September 2017

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Identification of temozolomide resistance factors in glioblastoma via integrative miRNA/mRNA regulatory network analysis

29 September 2017

1 reference

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MGMT testing--the challenges for biomarker-based glioma treatment

29 September 2017

1 reference

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Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines

29 September 2017

1 reference

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In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies.

29 September 2017

1 reference

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Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy

29 September 2017

1 reference

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Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

29 September 2017

1 reference

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Treatment of glioma by cisplatin-loaded nanogels conjugated with monoclonal antibodies against Cx43 and BSAT1.

29 September 2017

1 reference

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Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma

29 September 2017

1 reference

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Temozolomide and radiotherapy for newly diagnosed glioblastoma multiforme: a systematic review

29 September 2017

1 reference

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Unexpected low-dose toxicity of the universal solvent DMSO.

29 September 2017

1 reference

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Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Protective properties of radio-chemoresistant glioblastoma stem cell clones are associated with metabolic adaptation to reduced glucose dependence.

29 September 2017

1 reference

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Integrative genomic analysis of temozolomide resistance in diffuse large B-cell lymphoma

29 September 2017

1 reference

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Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

The somatic genomic landscape of glioblastoma

29 September 2017

1 reference

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Personalized treatment strategies in glioblastoma: MGMT promoter methylation status

29 September 2017

1 reference

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Antagonistic functional duality of cancer genes

29 September 2017

1 reference

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Temozolomide-modulated glioma proteome: role of interleukin-1 receptor-associated kinase-4 (IRAK4) in chemosensitivity

29 September 2017

1 reference

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OpenCFU, a new free and open-source software to count cell colonies and other circular objects

29 September 2017

1 reference

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The treatment of glioblastomas: a systematic update on clinical Phase III trials.

29 September 2017

1 reference

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Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma

29 September 2017

1 reference

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Alkylation sensitivity screens reveal a conserved cross-species functionome

29 September 2017

1 reference

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Why imatinib remains an exception of cancer research

29 September 2017

1 reference

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Temozolomide and unusual indications: review of literature.

29 September 2017

1 reference

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Immortalization and malignant transformation of eukaryotic cells.

29 September 2017

1 reference

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Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

STAT3 inhibition overcomes temozolomide resistance in glioblastoma by downregulating MGMT expression

29 September 2017

1 reference

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Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Bioenergetics pathways and therapeutic resistance in gliomas: emerging role of mitochondria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Is carcinogenesis a form of speciation?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Temozolomide-induced modification of the CXC chemokine network in experimental gliomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Chromosomal instability confers intrinsic multidrug resistance.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

The evolutionary mechanism of cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Defining 'chromosomal instability'.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Cancer drug resistance: the central role of the karyotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Genetic alterations associated with acquired temozolomide resistance in SNB-19, a human glioma cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Chromosomal alterations cause the high rates and wide ranges of drug resistance in cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Contribution of gap junctional communication between tumor cells and astroglia to the invasion of the brain parenchyma by human glioblastomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Step-wise and punctuated genome evolution drive phenotype changes of tumor cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Glioma cells escaped from cytotoxicity of temozolomide and vincristine by communicating with human astrocytes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Treatment of poorly differentiated glioma using a combination of monoclonal antibodies to extracellular connexin-43 fragment, temozolomide, and radiotherapy.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Karyotypically distinct U251, U373, and SNB19 glioma cell lines are of the same origin but have different drug treatment sensitivities.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858898

10.1186/S12935-016-0311-8

4 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27158244%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27158244%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

PubMed publication ID

27158244

1 reference