(Q36876670)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17378545%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

Pyrogallol-based molecules as potent inhibitors of the antiapoptotic Bcl-2 proteins (English)

1 reference

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27 December 2019

1

1 reference

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27 December 2019

Krzysztof Krajewski

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17378545%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Chao-Yie Yang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17378545%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Zaneta Nikolovska-Coleska

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17378545%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Jie Guo

4

1 reference

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27 December 2019

Su Qiu

5

1 reference

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27 December 2019

Renxiao Wang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17378545%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Wei Gao

7

1 reference

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27 December 2019

Guoping Wang

8

1 reference

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27 December 2019

Jeanne Stuckey

9

1 reference

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27 December 2019

Sheng Jiang

11

1 reference

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27 December 2019

Peter P Roller

12

1 reference

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27 December 2019

Shaomeng Wang

13

1 reference

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27 December 2019

language of work or name

English

0 references

publication date

23 March 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17378545%20AND%20SRC:MED&resulttype=core&format=json

Journal of Medicinal Chemistry

27 December 2019

published in

1 reference

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27 December 2019

volume

50

1 reference

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27 December 2019

page(s)

1723-1726

1 reference

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27 December 2019

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17378545%20AND%20SRC:MED&resulttype=core&format=json

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

27 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Solution structure of the antiapoptotic protein bcl-2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

From bench to clinic with apoptosis-based therapeutic agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

The Bcl-2 protein family: arbiters of cell survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

BCL-2 family: regulators of cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Bcl-2 family proteins: strategies for overcoming chemoresistance in cancer

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2536619

Recent progress on the regulation of apoptosis by Bcl-2 family members

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17378545

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM061400L

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17378545%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17378545%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference