(Q36877059)

16 August 2017

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title

Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis? (English)

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16 August 2017

Robert J Gillies

1

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16 August 2017

Robert A Gatenby

series ordinal

2

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16 August 2017

publication date

1 June 2007

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Journal of Bioenergetics and Biomembranes

16 August 2017

published in

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16 August 2017

volume

39

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16 August 2017

issue

3

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16 August 2017

page(s)

251-257

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https://scigraph.springernature.com/pub.10.1007/s10863-007-9085-y

16 August 2017

exact match

0 references

cites work

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Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells

21 January 2018

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Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors

21 January 2018

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The histological structure of some human lung cancers and the possible implications for radiotherapy

21 January 2018

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Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast

21 January 2018

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An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumor cells.

21 January 2018

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The number and distribution of capillaries in muscles with calculations of the oxygen pressure head necessary for supplying the tissue

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12 December 2020

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12 December 2020

Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development

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12 December 2020

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12 December 2020

An evolutionary model of carcinogenesis

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12 December 2020

Oncogenes in tumor metabolism, tumorigenesis, and apoptosis

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12 December 2020

Detection of resistance to imatinib by metabolic profiling: clinical and drug development implications

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12 December 2020

Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer.

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12 December 2020

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy.

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12 December 2020

Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted

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12 December 2020

Why do cancers have high aerobic glycolysis?

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12 December 2020

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

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12 December 2020

Cervix cancer oxygenation measured following external radiation therapy

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Glucose metabolism heterogeneity in human and mouse malignant glioma cell lines

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12 December 2020

The role of acidity in solid tumour growth and invasion

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12 December 2020

New directions for radiation biology research in cancer of the uterine cervix.

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12 December 2020

Biological and clinical significance of cathepsin D in breast cancer metastasis

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12 December 2020

A reaction-diffusion model of cancer invasion.

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12 December 2020

Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors.

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12 December 2020

Increased release of tumour cells by collagenase at acid pH: a possible mechanism for metastasis

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12 December 2020

Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells.

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12 December 2020

Pericellular pH affects distribution and secretion of cathepsin B in malignant cells

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12 December 2020

Why are cancers acidic? A carrier-mediated diffusion model for H+ transport in the interstitial fluid

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12 December 2020

Heterogeneity of tumor oxygenation: relationship to tumor necrosis, tumor size, and metastasis

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12 December 2020

Breast cancer cells have a high capacity to acidify extracellular milieu by a dual mechanism

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12 December 2020

A hybrid mathematical model of solid tumour invasion: the importance of cell adhesion

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12 December 2020

Characterization of very acidic phagosomes in breast cancer cells and their association with invasion

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12 December 2020

Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

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12 December 2020

Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas

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12 December 2020

Fluctuations in pO2 in irradiated human melanoma xenografts

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12 December 2020

A genetic model for colorectal tumorigenesis

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12 December 2020

Combined vascular and extracellular pH imaging of solid tumors

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12 December 2020

Glycolytic glioma cells with active glycogen synthase are sensitive to PTEN and inhibitors of PI3K and gluconeogenesis

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Akt stimulates aerobic glycolysis in cancer cells

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Biologic correlates of (18)fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography

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12 December 2020

Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation.

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12 December 2020

The physiological environment in cancer vascularization, invasion and metastasis.

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12 December 2020

Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats

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12 December 2020

Hypoxia, clonal selection, and the role of HIF-1 in tumor progression

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12 December 2020

[(18)F]FMISO and [(18)F]FDG PET imaging in soft tissue sarcomas: correlation of hypoxia, metabolism and VEGF expression

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12 December 2020

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12 December 2020

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12 December 2020

Physiological noise in murine solid tumours using T2*-weighted gradient-echo imaging: a marker of tumour acute hypoxia?

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12 December 2020

Comparing techniques of measuring tumor hypoxia in different murine tumors: Eppendorf pO2 Histograph, [3H]misonidazole binding and paired survival assay

1 reference

12 December 2020

10.1007/S10863-007-9085-Y

Identifiers

DOI

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16 August 2017

1 reference