(Q36877853)

16 August 2017

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title

Therapeutic peptides and peptidomimetics (English)

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16 August 2017

Kieber-Emmons T

1

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16 August 2017

Murali R

series ordinal

2

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16 August 2017

Greene MI

series ordinal

3

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16 August 2017

publication date

1 August 1997

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Current Opinion in Biotechnology

16 August 2017

published in

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16 August 2017

volume

8

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16 August 2017

issue

4

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16 August 2017

page(s)

435-441

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Discovery of novel intracellular receptor modulating drugs

16 August 2017

cites work

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7 January 2021

The chemistry of peroxovanadium compounds relevant to insulin mimesis

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7 January 2021

Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

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7 January 2021

Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090

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7 January 2021

A paradigm for drug discovery using a conformation from the crystal structure of a presentation scaffold

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7 January 2021

Single chain human interleukin 5 and its asymmetric mutagenesis for mapping receptor binding sites

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7 January 2021

Minimization of a polypeptide hormone

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7 January 2021

Synthesis of potent cyclic hexapeptide NK-1 antagonists. Use of a minilibrary in transforming a peptidal somatostatin receptor ligand into an NK-1 receptor ligand via a polyvalent peptidomimetic

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7 January 2021

Selection of a peptide with affinity for the tumor-associated TAG72 antigen from a phage-displayed library

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7 January 2021

The 'peptoid' approach to the design of non-peptide, small molecule agonists and antagonists of neuropeptides

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7 January 2021

Identifying small-molecule lead compounds: the screening approach to drug discovery

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7 January 2021

New approaches and technologies in drug design and discovery.

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7 January 2021

Macromolecular versus small-molecule therapeutics: drug discovery, development and clinical considerations

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7 January 2021

A solution-phase strategy for the synthesis of chemical libraries containing small organic molecules: a universal and dipeptide mimetic template

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7 January 2021

Selection of chymotrypsin inhibitors from a conformationally-constrained combinatorial peptide library

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7 January 2021

Novel cyclic analogs of angiotensin II with cyclization between positions 5 and 7: conformational and biological implications

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7 January 2021

Conformational mimicry: synthesis and solution conformation of a cyclic somatostatin hexapeptide containing a tetrazole cis amide bond surrogate

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7 January 2021

The use of topographical constraints in receptor mapping: investigation of the topographical requirements of the tryptophan 30 residue for receptor binding of Asp-Tyr-D-Phe-Gly-Trp-(N-Me)Nle-Asp-Phe-NH2 (SNF 9007), a cholecystokinin (26-33) analogue

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7 January 2021

Molecular recognition of peptide and non-peptide ligands by the extracellular domains of neurohypophysial hormone receptors

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7 January 2021

A Novel Bicyclic Enzyme Inhibitor as a Consensus Peptidomimetic for the Receptor-Bound Conformations of 12 Peptidic Inhibitors of HIV-1 Protease

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7 January 2021

Crystallographic studies on the binding modes of P2-P3 butanediamide renin inhibitors

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7 January 2021

Constrained peptides as binding entities

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7 January 2021

Small peptides as potent mimetics of the protein hormone erythropoietin

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7 January 2021

Rational design of granulocyte-macrophage colony-stimulating factor antagonist peptides

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7 January 2021

Small peptide mimics of nerve growth factor bind TrkA receptors and affect biological responses

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7 January 2021

De novo antimicrobial peptides with low mammalian cell toxicity

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7 January 2021

Branched synthetic constructs that mimic the physico-chemical properties of apolipoprotein AI in reconstituted high-density lipoproteins

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7 January 2021

Design and development of a vasoactive intestinal peptide analog as a novel therapeutic for bronchial asthma

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7 January 2021

Structure-activity relationships for macrocyclic peptidomimetic inhibitors of HIV-1 protease

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7 January 2021

Conformational analysis of cyclic hexapeptides designed as constrained ligands for the SH2 domain of the p85 subunit of phosphatidylinositol-3-OH kinase

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7 January 2021

Structure based design and characterization of peptides that inhibit IgE binding to its high-affinity receptor

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7 January 2021

Recent developments in retro peptides and proteins--an ongoing topochemical exploration

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7 January 2021

Synthetic CD4 exocyclic peptides antagonize CD4 holoreceptor binding and T cell activation

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7 January 2021

Synthetic CD4 exocyclics inhibit binding of human immunodeficiency virus type 1 envelope to CD4 and virus replication in T lymphocytes

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7 January 2021

A superactive peptidomimetic analog of a farnesylated dodecapeptide yeast pheromone

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7 January 2021

A mimetic of the RGDF-peptide [arginine-glycine-aspartic acid-phenylalanine] blocks aggregation and flow-induced platelet deposition on severely injured stenotic arterial wall. Effects on different animal models and in humans

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7 January 2021

Antithrombotic agents: from RGD to peptide mimetics.

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7 January 2021

Anti-idiotypic antibody as an oestrogen mimetic in vivo: stimulation of creatine kinase specific activity in rat animal models.

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7 January 2021

Therapeutic potential of antiidiotypic single chain antibodies with yeast killer toxin activity

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7 January 2021

SH2 and SH3 domains: potential targets for anti-cancer drug design

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7 January 2021

Conformationally constrained phosphotyrosyl mimetics designed as monomeric Src homology 2 domain inhibitors

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7 January 2021

Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

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7 January 2021

CAAX peptidomimetic FTI-244 decreases platelet-derived growth factor receptor tyrosine phosphorylation levels and inhibits stimulation of phosphatidylinositol 3-kinase but not mitogen-activated protein kinase

1 reference

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7 January 2021

Novel tricyclic inhibitors of farnesyl protein transferase. Biochemical characterization and inhibition of Ras modification in transfected Cos cells

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7 January 2021

Activated Drosophila Ras1 is selectively suppressed by isoprenyl transferase inhibitors

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7 January 2021

A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processing

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7 January 2021

Peptide mimicry of the meningococcal group C capsular polysaccharide

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7 January 2021

Peptide mimicry of adenocarcinoma-associated carbohydrate antigens

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7 January 2021

Peptide mimicry of carbohydrate epitopes on human immunodeficiency virus

1 reference

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7 January 2021

Thrombin active site inhibitors

1 reference

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7 January 2021

10.1016/S0958-1669(97)80065-1

Identifiers

DOI

1 reference

release_upiqybtbabablfebdumqkn5qxy

16 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/upiqybtbabablfebdumqkn5qxy

24 November 2022

mapped directly with Wikidata item

1 reference