(Q36887564)

English

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors.

scientific article published on 23 July 2007

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2 January 2020

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Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors (English)

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2 January 2020

Cécile Ingueneau

3

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2 January 2020

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A Negre-Salvayre

1

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2 January 2020

C Coatrieux

2

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R Salvayre

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23 July 2007

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2 January 2020

British Journal of Pharmacology

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153

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2 January 2020

1

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2 January 2020

6-20

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2 January 2020

4-Hydroxynonenal-induced apoptosis in rat hepatic stellate cells: mechanistic approach

1 reference

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Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells

1 reference

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Modulation of antioxidant gene expression by 4-hydroxynonenal: atheroprotective role of the Nrf2/ARE transcription pathway

1 reference

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Age-dependent inhibition of proteasome chymotrypsin-like activity in the retina

1 reference

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Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal

1 reference

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Protein adducts generated from products of lipid oxidation: focus on HNE and one.

1 reference

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Iron: a new target for pharmacological intervention in neurodegenerative diseases

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Clinical oxidation parameters of aging

1 reference

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Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal

1 reference

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Amyloid beta peptide, 4-hydroxynonenal and apoptosis

1 reference

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Enzyme-linked immunosorbent assay for 4-hydroxynonenal-histidine conjugates

1 reference

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Antioxidant treatment ameliorates respiratory syncytial virus-induced disease and lung inflammation

1 reference

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Advanced glycation endproducts (AGEs): Pharmacological inhibition in diabetes

1 reference

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Clinical applications of circulating oxidized low-density lipoprotein biomarkers in cardiovascular disease

1 reference

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29 September 2017

Lipoxidation-derived reactive carbonyl species as potential drug targets in preventing protein carbonylation and related cellular dysfunction

1 reference

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29 September 2017

Apc mutation induces resistance of colonic cells to lipoperoxide-triggered apoptosis induced by faecal water from haem-fed rats

1 reference

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29 September 2017

Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice

1 reference

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Resveratrol--a boon for treating Alzheimer's disease?

1 reference

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29 September 2017

Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species

1 reference

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29 September 2017

Oxidized protein degradation and repair in ageing and oxidative stress.

1 reference

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29 September 2017

Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity

1 reference

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29 September 2017

Analytical methods for trace levels of reactive carbonyl compounds formed in lipid peroxidation systems

1 reference

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29 September 2017

Hydrazine compounds inhibit glycation of low-density lipoproteins and prevent the in vitro formation of model foam cells from glycolaldehyde-modified low-density lipoproteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Oxidized low-density lipoprotein biomarkers in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Methylglyoxal comes of AGE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis.

1 reference

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29 September 2017

Carnosine and carnosine-related antioxidants: a review

1 reference

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Molecular pathology of aging and its implications for senescent coronary atherosclerosis

1 reference

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ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation

1 reference

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29 September 2017

Low-molecular weight advanced glycation end products: markers of tissue AGE accumulation and more?

1 reference

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29 September 2017

Pyridoxamine as a multifunctional pharmaceutical: targeting pathogenic glycation and oxidative damage.

1 reference

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29 September 2017

The antioxidant N-acetylcysteine prevents accelerated atherosclerosis in uremic apolipoprotein E knockout mice

1 reference

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29 September 2017

Nuclear factor kappaB signaling in atherogenesis.

1 reference

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29 September 2017

Inhibition of NFkappaB activation and IL-8 expression in human bronchial epithelial cells by acrolein.

1 reference

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29 September 2017

Catalytic site-specific inhibition of the 20S proteasome by 4-hydroxynonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

The clinical relevance of advanced glycation endproducts (AGE) and recent developments in pharmaceutics to reduce AGE accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Signaling kinases modulated by 4-hydroxynonenal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Reactions of 4-hydroxynonenal with proteins and cellular targets

1 reference

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29 September 2017

Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases

1 reference

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29 September 2017

4-hydroxynonenal and regulation of cell cycle: effects on the pRb/E2F pathway

1 reference

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29 September 2017

NF-kappaB activation mechanism of 4-hydroxyhexenal via NIK/IKK and p38 MAPK pathway

1 reference

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29 September 2017

Mass spectrometry for detection of 4-hydroxy-trans-2-nonenal (HNE) adducts with peptides and proteins.

1 reference

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29 September 2017

Induction of endothelial apoptosis by 4-hydroxyhexenal

1 reference

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Drugs used in hypertensive diseases in pregnancy

1 reference

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29 September 2017

Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy

1 reference

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Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts

1 reference

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Neuronal and glial calcium signaling in Alzheimer's disease

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29 September 2017

4-hydroxynonenal as a bioactive marker of pathophysiological processes

1 reference

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29 September 2017

The proteasomal system and HNE-modified proteins.

1 reference

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29 September 2017

Basic aspects of the biochemical reactivity of 4-hydroxynonenal

1 reference

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Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling

1 reference

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29 September 2017

Protein carbonylation in human diseases

1 reference

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Hepatotoxicity and Mechanism of Action of Haloalkanes: Carbon Tetrachloride as a Toxicological Model

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29 September 2017

4-Hydroxy-2-nonenal: a product and mediator of oxidative stress

1 reference

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29 September 2017

Oxidative stress in Parkinson's disease

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Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products.

1 reference

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Oxidative stress in viral and alcoholic hepatitis

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29 September 2017

Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome.

1 reference

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Oxidative stress in chronic renal failure as a cardiovascular risk factor

1 reference

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Chlamydia pneumoniae activates IKK/I kappa B-mediated signaling, which is inhibited by 4-HNE and following primary exposure

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Activation of PKC-beta isoforms mediates HNE-induced MCP-1 release by macrophages

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29 September 2017

Advanced glycation end product precursors impair epidermal growth factor receptor signaling.

1 reference

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Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation

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29 September 2017

4-Hydroxynonenal in the pathomechanisms of oxidative stress

1 reference

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29 September 2017

Phenolic antioxidants trolox and caffeic acid modulate the oxidized LDL-induced EGF-receptor activation

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Ebselen prevents early alcohol-induced liver injury in rats

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29 September 2017

Evidence for inducible nitric-oxide synthase expression and activity in vascular smooth muscle of streptozotocin-diabetic rats

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29 September 2017

Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part I--effects of proliferative senescence

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29 September 2017

The oxidative modification hypothesis of atherogenesis: an overview

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29 September 2017

Glycoxidation and lipoxidation in atherogenesis

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29 September 2017

Role of reactive aldehyde in cardiovascular diseases

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29 September 2017

Oxidized LDLs alter the activity of the ubiquitin-proteasome pathway: potential role in oxidized LDL-induced apoptosis.

1 reference

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29 September 2017

Proteasome inhibition in neuronal cells induces a proinflammatory response manifested by upregulation of cyclooxygenase-2, its accumulation as ubiquitin conjugates, and production of the prostaglandin PGE(2).

1 reference

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29 September 2017

4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition

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29 September 2017

4-Hydroxynonenal prevents NF-kappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis.

1 reference

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29 September 2017

Activation of EGF receptor by oxidized LDL.

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29 September 2017

Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation

1 reference

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29 September 2017

4-hydroxynonenal specifically inhibits c-myb but does not affect c-fos expressions in HL-60 cells

1 reference

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29 September 2017

Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug

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29 September 2017

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

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29 September 2017

Inhibition of adenine nucleotide translocator by lipid peroxidation products

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29 September 2017

The pathogenesis of atherosclerosis: a perspective for the 1990s

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29 September 2017

Cytotoxicity and genotoxicity of lipid-oxidation products

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29 September 2017

Inactivation of lysosomal proteases by oxidized low density lipoprotein is partially responsible for its poor degradation by mouse peritoneal macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Modification of human serum low density lipoprotein by oxidation--characterization and pathophysiological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Lipid peroxidation and cancer: a critical reconsideration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Low density lipoprotein undergoes oxidative modification in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Biochemical, structural, and functional properties of oxidized low-density lipoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

The role of advanced glycosylation end-products in the pathogenesis of atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

29 September 2017

Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

27 June 2018

Mildly oxidized LDL induces activation of platelet-derived growth factor beta-receptor pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

27 June 2018

The angiotensin-converting enzyme inhibitor, fosinopril, and the angiotensin II receptor antagonist, losartan, inhibit LDL oxidation and attenuate atherosclerosis independent of lowering blood pressure in apolipoprotein E deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

27 June 2018

Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

27 June 2018

4-Hydroxynonenal modifies the effects of serum growth factors on the expression of the c-fos proto-oncogene and the proliferation of HeLa carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

27 June 2018

Effect of antioxidative vitamins on immune function with clinical applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

27 June 2018

Lipoprotein trafficking in vascular cells. Molecular Trojan horses and cellular saboteurs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

27 June 2018

Low density lipoprotein oxidation and its pathobiological significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

27 June 2018

Detection of new epitopes formed upon oxidation of low-density lipoprotein, lipoprotein (a) and very-low-density lipoprotein. Use of an antiserum against 4-hydroxynonenal-modified low-density lipoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

27 June 2018

Neuroprotective actions of a histidine analogue in models of ischemic stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

N-Acetylcysteine and ebselen but not nifedipine protected cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

4-Hydroxynonenal induces vascular smooth muscle cell apoptosis through mitochondrial generation of reactive oxygen species.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Protective effect of vitamin E supplements on experimental atherosclerosis is modest and depends on preexisting vitamin E deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Protective effect of N-acetyl-L-cysteine on amyloid beta-peptide-induced learning and memory deficits in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Desensitization of platelet-derived growth factor receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by aldehyde scavengers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Production of lipid peroxidation products in osteoarthritic tissues: new evidence linking 4-hydroxynonenal to cartilage degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Differential regulation of c-jun and CREB by acrolein and 4-hydroxynonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Losartan attenuates bleomycin-induced pulmonary fibrosis in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

4-Hydroxynonenal signalling to apoptosis in isolated rat hepatocytes: the role of PKC-delta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

The presence of molecular markers of in vivo lipid peroxidation in osteoarthritic cartilage: a pathogenic role in osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Reaction of pyridoxamine with malondialdehyde: mechanism of inhibition of formation of advanced lipoxidation end-products.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Effect of methylglyoxal on intracellular calcium levels and viability in renal tubular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

S-Adenosylmethionine (SAMe) attenuates acetaminophen hepatotoxicity in C57BL/6 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Cataract formation in a strain of rats selected for high oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Pyridoxal-aminoguanidine adduct is more effective than aminoguanidine in preventing neuropathy and cataract in diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Heme oxygenase attenuates allergen-induced airway inflammation and hyperreactivity in guinea pigs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Generation of fluorescent adducts of malondialdehyde and amino acids: toward an understanding of lipofuscin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Pyrrolidine dithiocarbamate reduces the severity of cerulein-induced murine acute pancreatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Involvement of advanced lipooxidation end products (ALEs) and protein oxidation in the apoptotic actions of nitric oxide in insulin secreting RINm5F cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Paradoxical Protective Effect of Aminoguanidine toward Low-Density Lipoprotein Oxidation: Inhibition of Apolipoprotein B Fragmentation without Preventing Its Carbonylation. Mechanism of Action of Aminoguanidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Anti-Hypertensive Agents Inhibit In Vivo the Formation of Advanced Glycation End Products and Improve Renal Damage in a Type 2 Diabetic Nephropathy Rat Model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF-kappaB activation in smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Astrocytes accumulate 4-hydroxynonenal adducts in murine scrapie and human Creutzfeldt-Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Homocysteine in chronic renal failure in relation to renal anemia and to oxidative stress parameters 4-hydroxynonenal and malondialdehyde.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Damaged interlobular bile ducts in primary biliary cirrhosis show reduced expression of glutathione-S-transferase-pi and aberrant expression of 4-hydroxynonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Cellular lipid peroxidation end-products induce apoptosis in human lens epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Chelating activity of advanced glycation end-product inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Transfection of mGSTA4 in HL-60 cells protects against 4-hydroxynonenal-induced apoptosis by inhibiting JNK-mediated signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

4-Hydroxynonenal-modified amyloid-beta peptide inhibits the proteasome: possible importance in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

The antihypertensive hydralazine is an efficient scavenger of acrolein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Polyclonal antibodies to a fluorescent 4-hydroxy-2-nonenal (HNE)-derived lysine-lysine cross-link: characterization and application to HNE-treated protein and in vitro oxidized low-density lipoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Kinetics and mechanism of the reaction of aminoguanidine with the alpha-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

A 1-hour enzyme-linked immunosorbent assay for quantitation of acrolein- and hydroxynonenal-modified proteins by epitope-bound casein matrix method.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Antiatherosclerotic and antioxidative effects of captopril in apolipoprotein E-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Protective effects of carnosine against malondialdehyde-induced toxicity towards cultured rat brain endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Role of IkappaBalpha ubiquitination in signal-induced activation of NFkappaB in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199390

4 September 2018

Inhibition of HeLa cell proliferation by 4-hydroxynonenal is associated with enhanced expression of the c-fos oncogene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyridoxamine, an inhibitor of advanced glycation reactions, also inhibits advanced lipoxidation reactions. Mechanism of action of pyridoxamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

U-101033E (2,4-diaminopyrrolopyrimidine), a potent inhibitor of membrane lipid peroxidation as assessed by the production of 4-hydroxynonenal, malondialdehyde, and 4-hydroxynonenal--protein adducts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of human low-density lipoprotein by the lipid peroxidation product 4-hydroxynonenal

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-Hydroxyhexenal: a lipid peroxidation product derived from oxidized docosahexaenoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyrrole formation from 4-hydroxynonenal and primary amines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of HeLa cell growth by physiological concentrations of 4-hydroxynonenal

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of epitopes recognized by 4-hydroxy-2-nonenal specific antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-Jun N-terminal kinase, caspase-3, and p21-activated kinase 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptors for oxidized low density lipoprotein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant activity of vitamin B6 delays homocysteine-induced atherosclerosis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of autoantibodies in human plasma recognizing an apoB-100 LDL receptor binding site peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The in vitro effects of captopril on the levels of lipid peroxidation and glutathione of erythrocytes in type II diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies for detection of 4-hydroxynonenal modified proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased levels of 4-hydroxynonenal modified proteins in plasma of children with autoimmune diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein carbonyl measurement by a sensitive ELISA method

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HDL and ApoA prevent cell death of endothelial cells induced by oxidized LDL

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoguanidine inhibits semicarbazide-sensitive amine oxidase activity: implications for advanced glycation and diabetic complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical demonstration of enzymatically modified human LDL and its colocalization with the terminal complement complex in the early atherosclerotic lesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17643134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0707395

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643134%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643134%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643134%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

ResearchGate publication ID

0 references

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