(Q36898970)

English

Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus

scientific article published on 21 July 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

DNA methylation

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author name string

Vincenzo Giambra

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Sabrina Volpi

2

1 reference

Europe PubMed Central

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17 August 2017

Alexander V Emelyanov

3

1 reference

Europe PubMed Central

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17 August 2017

David Pflugh

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Alfred L M Bothwell

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Paolo Norio

6

1 reference

Europe PubMed Central

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17 August 2017

Yuhong Fan

7

1 reference

Europe PubMed Central

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17 August 2017

Zhongliang Ju

8

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Arthur I Skoultchi

9

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Richard R Hardy

10

1 reference

Europe PubMed Central

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17 August 2017

Domenico Frezza

11

1 reference

Europe PubMed Central

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17 August 2017

Barbara K Birshtein

12

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17 August 2017

language of work or name

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publication date

21 July 2008

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Europe PubMed Central

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17 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

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17 August 2017

28

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Europe PubMed Central

PMC publication ID

17 August 2017

19

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

6123-6133

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Evidence for physical interaction between the immunoglobulin heavy chain variable region and the 3' regulatory region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Pax5: the guardian of B cell identity and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Elucidation of IgH intronic enhancer functions via germ-line deletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Epigenetic mechanisms that regulate antigen receptor gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

The 3' IgH regulatory region: a complex structure in a search for a function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Ig heavy chain expression and class switching in vitro from an allele lacking the 3' enhancers DNase I-hypersensitive hs3A and hs1,2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Dyad symmetry within the mouse 3' IgH regulatory region includes two virtually identical enhancers (C alpha3'E and hs3).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3' alpha enhancer at early stages of B-cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Identification of 3' alpha-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Expression of the J chain gene during B cell differentiation is inversely correlated with DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Methylation patterns of immunoglobulin genes in lymphoid cells: correlation of expression and differentiation with undermethylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Myeloma mutant with a novel 3' flanking region: loss of normal sequence and insertion of repetitive elements leads to decreased transcription but normal processing of the alpha heavy-chain gene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

29 September 2017

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

27 June 2018

Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

27 June 2018

DNA regions flanking the mouse Ig 3' alpha enhancer are differentially methylated and DNAase I hypersensitive during B cell differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

27 June 2018

Isolation and characterization of a cloned growth factor dependent macrophage cell line, BAC1.2F5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

27 June 2018

Identification of Pax5 target genes in early B cell differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

4 September 2018

Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

4 September 2018

Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

4 September 2018

Characterization of B lymphopoiesis in mouse bone marrow and spleen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

4 September 2018

Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

4 September 2018

Palindromic structure of the IgH 3'locus control region.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

4 September 2018

Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

4 September 2018

Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin κ-chain locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547000

4 December 2018

The Ig heavy chain intronic enhancer core region is necessary and sufficient to promote efficient class switch recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18644860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of IgH gene assembly: role of the intronic enhancer and 5'DQ52 region in targeting DHJH recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18644860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18644860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18644860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00233-08

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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