Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36903858)
Watch
English
Arkadia regulates tumor metastasis by modulation of the TGF-β pathway.
scientific article published on 6 March 2013
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
title
Arkadia regulates tumor metastasis by modulation of the TGF-β pathway
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
main subject
tumor metastasis
1 reference
based on heuristic
litr
author
Marco A Briones-Orta
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
Chris D Madsen
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
Erik Sahai
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
Caroline S. Hill
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
author name string
Laurence Levy
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
Debipriya Das
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
Yigit Erker
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
language of work or name
English
0 references
publication date
6 March 2013
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
published in
Cancer Research
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
volume
73
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
issue
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
page(s)
1800-1810
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
cites work
Directed cell invasion and migration during metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Enhancement of TGF-β signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Quantification of transendothelial migration using three-dimensional confocal microscopy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Exploring anti-TGF-β therapies in cancer and fibrosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Exploring the genomes of cancer cells: progress and promise
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Hallmarks of Cancer: The Next Generation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Transforming growth factor-β and the hallmarks of cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Smad3 protein levels are modulated by Ras activity and during the cell cycle to dictate transforming growth factor-beta responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Transforming growth factor-beta2 is a molecular determinant for site-specific melanoma metastasis in the brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Roles of TGFbeta in metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
TGFbeta in Cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
How the Smads regulate transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
ID genes mediate tumor reinitiation during breast cancer lung metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Illuminating the metastatic process
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Cancer metastasis: building a framework
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Dual role of SnoN in mammalian tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
SnoN co-repressor binds and represses smad7 gene promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Alterations in components of the TGF-beta superfamily signaling pathways in human cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Specificity and versatility in tgf-beta signaling through Smads
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Repression of endogenous Smad7 by Ski.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Ski and SnoN: negative regulators of TGF-beta signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Recognition of phosphorylated-Smad2-containing complexes by a novel Smad interaction motif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
The Ski protein family is required for MeCP2-mediated transcriptional repression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
29 September 2017
Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
27 June 2018
Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
4 September 2018
A novel Cripto-related protein reveals an essential role for EGF-CFCs in Nodal signalling in Xenopus embryos.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672972
retrieved
4 September 2018
EGF stimulates an increase in actin nucleation and filament number at the leading edge of the lamellipod in mammary adenocarcinoma cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23467611
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/0008-5472.CAN-12-1916
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
PMC publication ID
3672972
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
PubMed publication ID
23467611
1 reference
stated in
Europe PubMed Central
PMC publication ID
3672972
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
