(Q36917600)

17 August 2017

A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress (English)

1 reference

17 August 2017

Yunhao Liu

1

1 reference

17 August 2017

Caitlin Collins

2

1 reference

17 August 2017

William B Kiosses

3

1 reference

17 August 2017

Ann M Murray

4

1 reference

17 August 2017

Monika Joshi

5

1 reference

17 August 2017

Tyson R Shepherd

6

1 reference

17 August 2017

Ernesto J Fuentes

7

1 reference

17 August 2017

Ellie Tzima

8

1 reference

17 August 2017

language of work or name

English

0 references

publication date

3 June 2013

1 reference

17 August 2017

Journal of Cell Biology

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17 August 2017

201

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17 August 2017

6

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17 August 2017

863-873

1 reference

describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3678169/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Structural and thermodynamic analysis of PDZ-ligand interactions

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Spatio-temporal Rho GTPase signaling - where are we now?

29 September 2017

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The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion

29 September 2017

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Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1).

29 September 2017

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Distal Interactions within the par3−VE-Cadherin Complex,

29 September 2017

1 reference

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Nox proteins in signal transduction

29 September 2017

1 reference

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PECAM-1 is necessary for flow-induced vascular remodeling

29 September 2017

1 reference

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Cell polarity triggered by cell-cell adhesion via E-cadherin

29 September 2017

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Mechanotransduction in vascular physiology and atherogenesis

29 September 2017

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Compartmentalization of redox signaling through NADPH oxidase-derived ROS.

29 September 2017

1 reference

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Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation

29 September 2017

1 reference

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VEGF signaling through NADPH oxidase-derived ROS.

29 September 2017

1 reference

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Catching a GEF by its tail

29 September 2017

1 reference

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VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

29 September 2017

1 reference

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A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells

29 September 2017

1 reference

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Coupling receptor tyrosine kinases to Rho GTPases--GEFs what's the link

29 September 2017

1 reference

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Nox1-dependent reactive oxygen generation is regulated by Rac1

29 September 2017

1 reference

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The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis

29 September 2017

1 reference

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Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response

29 September 2017

1 reference

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Rho GTPases and the control of cell behaviour

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex

29 September 2017

1 reference

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Polarized downregulation of the paxillin-p130CAS-Rac1 pathway induced by shear flow

29 September 2017

1 reference

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Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

29 September 2017

1 reference

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PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Par proteins: partners in polarization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Rho GTPases in cell biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Localized Rac activation dynamics visualized in living cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

A Rac1 effector site controlling mitogenesis through superoxide production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

A model of localised Rac1 activation in endothelial cells due to fluid flow.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Comparison of the lateral tail vein and the retro-orbital venous sinus as routes of intravenous drug delivery in a transgenic mouse model.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

p47phox-dependent NADPH oxidase regulates flow-induced vascular remodeling

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678169

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201207115

Rapid displacement of vimentin intermediate filaments in living endothelial cells exposed to flow

21 January 2018

1 reference

12 December 2020

Reactive oxygen species are involved in shear stress-induced intercellular adhesion molecule-1 expression in endothelial cells

1 reference

12 December 2020

Shear-induced tyrosine phosphorylation in endothelial cells requires Rac1-dependent production of ROS

1 reference

12 December 2020

Stabilization of brain microvascular endothelial barrier function by shear stress involves VE-cadherin signaling leading to modulation of pTyr-occludin levels

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.201207115

1 reference

17 August 2017

1 reference

17 August 2017

1 reference