(Q36922987)

17 August 2017

1 reference

title

Role of phosphoinositide 3-kinase signaling in autoimmunity (English)

1 reference

17 August 2017

Jean S Oak

1

1 reference

PubMed ID

17729037

17 August 2017

David A Fruman

series ordinal

2

1 reference

17 August 2017

1 September 2007

1 reference

17 August 2017

1 reference

17 August 2017

40

1 reference

17 August 2017

6

1 reference

17 August 2017

433-441

1 reference

Synthesis and function of 3-phosphorylated inositol lipids

17 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Phosphoinositide 3-kinase: diverse roles in immune cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Enhanced T cell proliferation in mice lacking the p85beta subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Forkhead-box transcription factors and their role in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Immune regulation by Foxo transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Regulation of quiescence in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Pten is essential for embryonic development and tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Compound heterozygosity for Pten and SHIP augments T-dependent humoral immune responses and cytokine production by CD(4+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Loss of a single allele of SHIP exacerbates the immunopathology of Pten heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Distinct molecular mechanism for initiating TRAF6 signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Cbl-b regulates the CD28 dependence of T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Resistance to CD4+CD25+ regulatory T cells and TGF-beta in Cbl-b-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

'Vive la Résistance!'--the PI3K-Akt pathway can determine target sensitivity to regulatory T cell suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

PI3Kgamma inhibition: towards an 'aspirin of the 21st century'?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Class IB-phosphatidylinositol 3-kinase (PI3K) deficiency ameliorates IA-PI3K-induced systemic lupus but not T cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Lymphocytic infiltration and enlargement of the lacrimal glands: a new subtype of primary Sjögren's syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

T cell clones from a Sjögren's syndrome salivary gland biopsy produce high levels of IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Phosphatidylinositol 3-kinase p85 adaptor function in T-cells. Co-stimulation and regulation of cytokine transcription independent of associated p110.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Identification of a novel PTEN mutation (L139X) in a patient with Cowden disease and Sjögren's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Regulation of tumor necrosis factor alpha-mediated apoptosis of rheumatoid arthritis synovial fibroblasts by the protein kinase Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Phosphoinositide 3-kinases as targets for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Phosphoinositide 3-kinase signalling--which way to target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Essential role for the p110delta phosphoinositide 3-kinase in the allergic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Expression of Active Protein Kinase B in T Cells Perturbs Both T and B Cell Homeostasis and Promotes Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464780

10.1080/08916930701464780

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17729037