(Q36930220)

English

Photo-activated azi-etomidate, a general anesthetic photolabel, irreversibly enhances gating and desensitization of gamma-aminobutyric acid type A receptors

scientific article published on January 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Photo-activated azi-etomidate, a general anesthetic photolabel, irreversibly enhances gating and desensitization of gamma-aminobutyric acid type A receptors (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

desensitization

1 reference

based on heuristic

inferred from title

author name string

Huijun Zhong

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Dirk Rüsch

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Stuart A Forman

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

1 January 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

108

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

103-112

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light.

1 reference

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29 September 2017

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

1 reference

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29 September 2017

Molecular and systemic mechanisms of general anaesthesia: the 'multi-site and multiple mechanisms' concept

1 reference

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29 September 2017

Neuroactive steroids have multiple actions to potentiate GABAA receptors

1 reference

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29 September 2017

Mechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure.

1 reference

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29 September 2017

Gating allosterism at a single class of etomidate sites on alpha1beta2gamma2L GABA A receptors accounts for both direct activation and agonist modulation

1 reference

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29 September 2017

Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: electrophysiology-coordinated photochemistry and mass spectrometry

1 reference

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

1 reference

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Coupled and uncoupled gating and desensitization effects by pore domain mutations in GABA(A) receptors.

1 reference

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29 September 2017

Molecular determinants for the action of general anesthetics at recombinant alpha(2)beta(3)gamma(2)gamma-aminobutyric acid(A) receptors.

1 reference

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29 September 2017

Modulation of GABA(A) receptor channel gating by pentobarbital

1 reference

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29 September 2017

Positive allosteric modulation by ultraviolet irradiation on GABA(A), but not GABA(C), receptors expressed in Xenopus oocytes

1 reference

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29 September 2017

Stereoselective effects of etomidate optical isomers on gamma-aminobutyric acid type A receptors and animals

1 reference

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29 September 2017

The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564603

29 September 2017

Which GABAA-receptor subtypes really occur in the brain?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564603

29 September 2017

Specific labeling and permanent activation of the retinal rod cGMP-activated channel by the photoaffinity analog 8-p-azidophenacylthio-cGMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564603

29 September 2017

Classic benzodiazepines modulate the open-close equilibrium in alpha1beta2gamma2L gamma-aminobutyric acid type A receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564603

27 June 2018

Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564603

27 June 2018

Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564603

27 June 2018

Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes.

1 reference

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27 June 2018

Etomidate potentiation of GABAA receptor gated current depends on the subunit composition.

1 reference

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27 June 2018

Increased sensitivity to etomidate in the elderly: initial distribution versus altered brain response.

1 reference

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27 June 2018

Modulation of a GABA-ergic inhibitory circuit in the in vitro hippocampus by etomidate isomers.

1 reference

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27 June 2018

Photoactivated 3-azioctanol irreversibly desensitizes muscle nicotinic ACh receptors via interactions at alphaE262.

1 reference

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4 September 2018

Anaesthetic binding sites for etomidate and propofol on a GABAA receptor model.

1 reference

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4 September 2018

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

1 reference

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Probing the reorganization of the nicotinic acetylcholine receptor during desensitization by time-resolved covalent labeling using [3H]AC5, a photoactivatable agonist

1 reference

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4 September 2018

R (+) etomidate and the photoactivable R (+) azietomidate have comparable anesthetic activity in wild-type mice and comparably decreased activity in mice with a N265M point mutation in the gamma-aminobutyric acid receptor beta3 subunit

1 reference

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4 September 2018

The GABA-A beta3 subunit mediates anaesthesia induced by etomidate

1 reference

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4 September 2018

The in vitro and in vivo enantioselectivity of etomidate implicates the GABAA receptor in general anaesthesia.

1 reference

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4 September 2018

2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels

1 reference

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4 September 2018

General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit.

1 reference

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4 September 2018

Probing the interactions between cAMP and cGMP in cyclic nucleotide-gated channels using covalently tethered ligands

1 reference

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4 September 2018

A hydrophobic photolabel inhibits nicotinic acetylcholine receptors via open-channel block following a slow step.

1 reference

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4 September 2018

Distinct loci mediate the direct and indirect actions of the anesthetic etomidate at GABA(A) receptors.

1 reference

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4 September 2018

Mechanisms of etomidate potentiation of GABAA receptor-gated currents in cultured postnatal hippocampal neurons.

1 reference

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4 September 2018

Identifiers

10.1097/01.ANES.0000296074.33999.52

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

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