(Q36940467)

English

In vivo manipulation of the bleomycin biosynthetic gene cluster in Streptomyces verticillus ATCC15003 revealing new insights into its biosynthetic pathway

scientific article published on 12 August 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

In vivo manipulation of the bleomycin biosynthetic gene cluster in Streptomyces verticillus ATCC15003 revealing new insights into its biosynthetic pathway (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Streptomyces verticillus

1 reference

1 reference

author name string

Ute Galm

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Liyan Wang

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Evelyn Wendt-Pienkowski

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Runying Yang

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Wen Liu

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Meifeng Tao

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Jane M Coughlin

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Ben Shen

8

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

12 August 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

full work available at URL

http://www.jbc.org/article/S0021925820642193/pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1074/jbc.m804971200?email=unpaywall_01@example.com

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

283

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

42

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

28236-28245

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

online access status

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1074/jbc.m804971200?email=unpaywall_01@example.com

access restriction status

1 reference

based on heuristic

inferred from online access status

Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis

1 reference

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29 September 2017

Crystal structure of DNA-bound Co(III)·bleomycin B2: Insights on intercalation and minor groove binding

1 reference

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29 September 2017

Glycopeptide antitumor antibiotic zorbamycin from Streptomyces flavoviridis ATCC 21892: strain improvement and structure elucidation

1 reference

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Recent developments towards the heterologous expression of complex bacterial natural product biosynthetic pathways.

1 reference

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Antitumor antibiotics: bleomycin, enediynes, and mitomycin

1 reference

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Bleomycins: towards better therapeutics

1 reference

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In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis.

1 reference

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Characterization of NovP and NovN: completion of novobiocin biosynthesis by sequential tailoring of the noviosyl ring

1 reference

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Integration site for Streptomyces phage phiBT1 and development of site-specific integrating vectors

1 reference

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PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

1 reference

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29 September 2017

Cloning and characterization of the bleomycin biosynthetic gene cluster from Streptomyces verticillus ATCC15003.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2568937

29 September 2017

The biosynthetic gene cluster for the anticancer drug bleomycin from Streptomyces verticillus ATCC15003 as a model for hybrid peptide-polyketide natural product biosynthesis

1 reference

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29 September 2017

Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2568937

29 September 2017

Generalized transduction in Streptomyces coelicolor

1 reference

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29 September 2017

Bleomycin: new perspectives on the mechanism of action

1 reference

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29 September 2017

Evidence that the extracytoplasmic function sigma factor sigmaE is required for normal cell wall structure in Streptomyces coelicolor A3(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2568937

29 September 2017

Copper-dependent cleavage of DNA by bleomycin

1 reference

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Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

1 reference

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29 September 2017

Chemistry of bleomycin. XVIII. carbon-13 NMR studies

1 reference

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29 September 2017

Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters

1 reference

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27 June 2018

The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2568937

27 June 2018

An oxidation domain in the BlmIII non-ribosomal peptide synthetase probably catalyzing thiazole formation in the biosynthesis of the anti-tumor drug bleomycin in Streptomyces verticillus ATCC15003.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2568937

27 June 2018

High efficiency intergeneric conjugal transfer of plasmid DNA from Escherichia coli to methyl DNA-restricting streptomycetes.

1 reference

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27 June 2018

Gene organization in the bleomycin-resistance region of the producer organism Streptomyces verticillus

1 reference

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27 June 2018

The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics

1 reference

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Heterologous production of epothilone C and D in Escherichia coli.

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Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering.

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BlmIII and BlmIV nonribosomal peptide synthetase-catalyzed biosynthesis of the bleomycin bithiazole moiety involving both in cis and in trans aminoacylation

1 reference

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'Streptomyces nanchangensis', a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters

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Identification and characterization of a type II peptidyl carrier protein from the bleomycin producer Streptomyces verticillus ATCC 15003.

1 reference

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4 September 2018

Total Synthesis of Bleomycin Group Antibiotics. Total Syntheses of Bleomycin Demethyl A2, Bleomycin A2, and Decarbamoyl Bleomycin Demethyl A2

1 reference

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21 January 2018

Transformation of Streptomyces erythraeus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18697737

12 December 2020

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DNA strand scission by bleomycin group antibiotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18697737

12 December 2020

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New antibiotics, bleomycin A and B

1 reference

https://pubmed.ncbi.nlm.nih.gov/18697737

12 December 2020

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Chemistry of bleomycin. XIX. Revised structures of bleomycin and phleomycin

1 reference

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12 December 2020

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Bleomycin Biosynthesis inStreptomyces verticillusATCC15003: A Model of Hybrid Peptide and Polyketide Biosynthesis

1 reference

11 May 2024

https://opencitations.net/index/api/v1/citations/10.1006/BIOO.1998.1131

Identifiers

10.1074/JBC.M804971200

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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