(Q36942279)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

Design, synthesis, and preliminary evaluation of doxazolidine carbamates as prodrugs activated by carboxylesterases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

author name string

David J Burkhart

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Benjamin L Barthel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Glen C Post

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Brian T Kalet

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Jordan W Nafie

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Tad H Koch

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

language of work or name

English

0 references

publication date

1 November 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

Journal of Medicinal Chemistry

22 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

volume

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

issue

24

1 reference

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22 December 2019

page(s)

7002-7012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

Hepatocellular carcinoma: therapy and prevention

22 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Novel formulations of taxanes: a review. Old wine in a new bottle?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Doxazolidine, a proposed active metabolite of doxorubicin that cross-links DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Opportunities for targeted therapies in hepatocellular carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

The power and potential of doxorubicin-DNA adducts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

29 September 2017

Capecitabine: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Enzyme-catalyzed activation of anticancer prodrugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Structural insights into CPT-11 activation by mammalian carboxylesterases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Synthesis and biological evaluation of novel prodrugs of anthracyclines for selective activation by the tumor-associated protease plasmin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Circumvention of P-GP MDR as a function of anthracycline lipophilicity and charge

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Molecular evolutionary analysis predicts the incidence of hepatocellular carcinoma in the United States and Japan

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Identification of the cytosolic carboxylesterase catalyzing the 5'-deoxy-5-fluorocytidine formation from capecitabine in human liver

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

Computerized determination of growth kinetic curves and doubling times from cells in microculture.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2569826

The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, capecitabine

4 September 2018

1 reference

12 December 2020

A methylester of the glucuronide prodrug DOX-GA3 for improvement of tumor-selective chemotherapy

1 reference

12 December 2020

A novel connector linkage applicable in prodrug design

1 reference

12 December 2020

Determination of cell number in monolayer cultures

1 reference

12 December 2020

Doxoform and Daunoform: anthracycline-formaldehyde conjugates toxic to resistant tumor cells

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM060597E

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

release_hdrmx7a6nbedzf7h5j7awg32cu

22 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hdrmx7a6nbedzf7h5j7awg32cu

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125253%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

PubMed publication ID

17125253

1 reference