(Q36943119)

English

Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness

scientific article published on 02 October 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

neoplastic invasiveness

1 reference

based on heuristic

inferred from title

author name string

Emy Behmoaram

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Krikor Bijian

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Su Jie

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Yingjie Xu

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Andrew Darnel

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Tarek A Bismar

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Moulay A Alaoui-Jamali

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

2 October 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

173

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1540-1550

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma

1 reference

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29 September 2017

The significance of proline-rich tyrosine kinase2 (Pyk2) on hepatocellular carcinoma progression and recurrence.

1 reference

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29 September 2017

Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Cellular characterization of a novel focal adhesion kinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Loss of proline-rich tyrosine kinase 2 function induces spreading and motility of epithelial prostate cells.

1 reference

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29 September 2017

Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Specific induction of pp125 focal adhesion kinase in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

The tyrosine kinase pyk2 promotes migration and invasion of glioma cells.

1 reference

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29 September 2017

Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Ligand-induced, p38-dependent apoptosis in cells expressing high levels of epidermal growth factor receptor and ErbB-2.

1 reference

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29 September 2017

Axis of evil: molecular mechanisms of cancer metastasis

1 reference

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29 September 2017

Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Tissue microarray sampling strategy for prostate cancer biomarker analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Differential regulation of components of the focal adhesion complex by heregulin: role of phosphatase SHP-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Inhibition of PYK2-induced actin cytoskeleton reorganization, PYK2 autophosphorylation and focal adhesion targeting by FAK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

The role of distinct p185neu extracellular subdomains for dimerization with the epidermal growth factor (EGF) receptor and EGF-mediated signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Variations of proline-rich kinase Pyk2 expression correlate with prostate cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Pyk2 and FAK differentially regulate progression of the cell cycle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Paxillin alpha and Crk-associated substrate exert opposing effects on cell migration and contact inhibition of growth through tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Integrin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Identification of a new Pyk2 target protein with Arf-GAP activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Control of adhesion-dependent cell survival by focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions

1 reference

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29 September 2017

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1 reference

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29 September 2017

Interaction of focal adhesion kinase with cytoskeletal protein talin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

29 September 2017

Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas

1 reference

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29 September 2017

Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily

1 reference

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29 September 2017

Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570143

27 June 2018

Preferential phosphorylation of focal adhesion kinase tyrosine 861 is critical for mediating an anti-apoptotic response to hyperosmotic stress

1 reference

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4 September 2018

Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma

1 reference

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4 September 2018

Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion

1 reference

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4 September 2018

Expression of tyrosine kinases FAK and Pyk2 in 331 human astrocytomas

1 reference

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4 September 2018

Expression analysis of protein tyrosine kinases of the FAK (focal adhesion kinase) family in osteosarcoma

1 reference

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4 September 2018

Focal adhesion kinase facilitates platelet-derived growth factor-BB-stimulated ERK2 activation required for chemotaxis migration of vascular smooth muscle cells

1 reference

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4 September 2018

Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.

1 reference

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4 September 2018

[Expression of proline-rich tyrosine kinase-2 (Pyk2) in gastric carcinoma and its significance]

1 reference

https://pubmed.ncbi.nlm.nih.gov/18832579

12 December 2020

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Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18832579

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell adhesion and focal adhesion kinase regulate insulin receptor substrate-1 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18832579

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium- and protein kinase C-dependent activation of the tyrosine kinase PYK2 by angiotensin II in vascular smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/18832579

12 December 2020

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Domain-specific Interactions between the p185neuand Epidermal Growth Factor Receptor Kinases Determine Differential Signaling Outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18832579

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal adhesion kinase in integrin-mediated signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18832579

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/18832579

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18832579

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2008.080292

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

0 references

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