(Q36945842)

17 August 2017

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title

The application of microbubbles for targeted drug delivery (English)

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17 August 2017

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1 reference

Joseph L Bull

1

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17 August 2017

language of work or name

English

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publication date

1 September 2007

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Expert Opinion on Drug Delivery

17 August 2017

published in

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17 August 2017

volume

4

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17 August 2017

issue

5

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17 August 2017

page(s)

475-493

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Cardiovascular bubble dynamics

17 August 2017

cites work

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Targeted therapeutic applications of acoustically active microspheres in the microcirculation

21 January 2018

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Microbubbles in medical imaging: current applications and future directions

21 January 2018

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Microbubble contrast agents: targeted ultrasound imaging and ultrasound-assisted drug-delivery applications

21 January 2018

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Numerical simulation of the flow-induced deformation of red blood cells

21 January 2018

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Optical monitoring of ultrasound-induced bioeffects in glass catfish

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Large deformation of red blood cell ghosts in a simple shear flow

21 January 2018

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Two-dimensional simulation of red blood cell deformation and lateral migration in microvessels.

21 January 2018

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Fluid mechanics of vascular systems, diseases, and thrombosis

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Microcirculation: Mechanics of Blood Flow in Capillaries

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Surfactant-spreading and surface-compression disturbance on a thin viscous film

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Distribution dynamics of perfluorocarbon delivery to the lungs: an intact rabbit model

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Respiratory fluid mechanics and transport processes

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.4.5.475

The effect of airway wall motion on surfactant delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Pressure gradient, not exposure duration, determines the extent of epithelial cell damage in a model of pulmonary airway reopening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Modelling drainage of the precorneal tear film after a blink.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

The use of ultrasound for drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Encapsulated ultrasound microbubbles: therapeutic application in drug/gene delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Ultrasound: mechanical gene transfer into plant cells by sonoporation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Interrelation between HeLa-S3 cell transfection and hemolysis in red blood cell suspension using pulsed ultrasound of various duty cycles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Binding and lysing of blood clots using MRX-408.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Multiphoton imaging of ultrasound/Optison mediated cerebrovascular effects in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Left heart opacification with peripheral venous injection of a new saccharide echo contrast agent in dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Noninvasive identification of acute myocardial ischemia and reperfusion with contrast ultrasound using intravenous perfluoropropane-exposed sonicated dextrose albumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Effect of coupled oscillations on microbubble behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Applications of lipid-coated microbubble ultrasonic contrast to tumor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Development of a novel method for synthesis of a polymeric ultrasound contrast agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Grafting of encapsulated BDNF-producing fibroblasts into the injured spinal cord without immune suppression in adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Microencapsulated liposomes in controlled drug delivery: strategies to modulate drug release and eliminate the burst effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Ligand-carrying gas-filled microbubbles: ultrasound contrast agents for targeted molecular imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Importance of adequate gas-mixing in contrast echocardiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

On-chip generation of microbubbles as a practical technology for manufacturing contrast agents for ultrasonic imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Clinical safety of SonoVue, a new contrast agent for ultrasound imaging, in healthy volunteers and in patients with chronic obstructive pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Evaluation of gas-filled microparticles and sonoporation as gene delivery system: feasibility study in rodent tumor models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Surface phase behavior and microstructure of lipid/PEG-emulsifier monolayer-coated microbubbles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Collapse and shedding transitions in binary lipid monolayers coating microbubbles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Lateral phase separation in lipid-coated microbubbles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Effect of microbubble ligation to cells on ultrasound signal enhancement: implications for targeted imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Dynamics of therapeutic ultrasound contrast agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Optical and acoustical observations of the effects of ultrasound on contrast agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Polymeric contrast agent with targeting potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Delivery of drugs with ultrasound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Endothelial cell delivery for cardiovascular therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its local effects on tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Biodegradation and biocompatibility of PLA and PLGA microspheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Influence of microbubble surface charge on capillary transit and myocardial contrast enhancement

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Internalization of microbubbles by tumor cells in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Simulation of cell rolling and adhesion on surfaces in shear flow: general results and analysis of selectin-mediated neutrophil adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Sialyl Lewis(x)/E-selectin-mediated rolling in a cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Quantifying rolling adhesion with a cell-free assay: E-selectin and its carbohydrate ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Sialyl Lewis(x)-mediated, PSGL-1-independent rolling adhesion on P-selectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Comparison of PSGL-1 microbead and neutrophil rolling: microvillus elongation stabilizes P-selectin bond clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Influence of cell deformation on leukocyte rolling adhesion in shear flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Development of a side-view chamber for studying cell-surface adhesion under flow conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

A stochastic model of leukocyte rolling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

The interaction between leukocytes and endothelium in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Characterization of biodegradable drug delivery vehicles with the adhesive properties of leukocytes II: effect of degradation on targeting activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Microbubble-enhanced ultrasound to deliver an antisense oligodeoxynucleotide targeting the human androgen receptor into prostate tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Ultrasound-targeted microbubble destruction augments protein delivery into testes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Targeted retroviral gene delivery using ultrasound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Gene therapy progress and prospects: ultrasound for gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Spatial and acoustic pressure dependence of microbubble-mediated gene delivery targeted using focused ultrasound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Gene transfer with microbubble ultrasound and plasmid DNA into skeletal muscle of mice: comparison between commercially available microbubble contrast agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

In vivo myocardial kinetics of air-filled albumin microbubbles during myocardial contrast echocardiography. Comparison with radiolabeled red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Myocardial contrast echocardiography can be used to assess the microvascular response to vascular endothelial growth factor-121.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Detection of individual microbubbles of an ultrasound contrast agent: fundamental and pulse inversion imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Targeted-microbubble binding selectively to GPIIb IIIa receptors of platelet thrombi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

The effect of polymer chain length and surface density on the adhesiveness of functionalized polymersomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Microparticle adhesive dynamics and rolling mediated by selectin-specific antibodies under flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Acoustic radiation force in vivo: a mechanism to assist targeting of microbubbles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Multi-modality imaging identifies key times for annexin V imaging as an early predictor of therapeutic outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Acoustic radiation force enhances targeted delivery of ultrasound contrast microbubbles: in vitro verification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Ultrasound radiation force enables targeted deposition of model drug carriers loaded on microbubbles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Deformable gas-filled microbubbles targeted to P-selectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Influence of microbubble shell properties on ultrasound signal: Implications for low-power perfusion imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

VIII. On the pressure developed in a liquid during the collapse of a spherical cavity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Intracranial clot lysis with intravenous microbubbles and transcranial ultrasound in swine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Evolving applications for contrast ultrasound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Correlation between sonochemistry of surfactant solutions and human leukemia cell killing by ultrasound and porphyrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Influence of injection site, microvascular pressure and ultrasound variables on microbubble-mediated delivery of microspheres to muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

The final stage of the collapse of a cavitation bubble close to a rigid boundary

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Targeted tissue transfection with ultrasound destruction of plasmid-bearing cationic microbubbles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Influence of lipid shell physicochemical properties on ultrasound-induced microbubble destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Interaction of diagnostic ultrasound with synthetic oligonucleotide-labeled perfluorocarbon-exposed sonicated dextrose albumin microbubbles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Direct numerical simulations of micro-bubble expansion in gas embolotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Microbubble expansion in a flexible tube.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Acoustic response of compliable microvessels containing ultrasound contrast agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Intracellular delivery of Bak BH3 peptide by microbubble-enhanced ultrasound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Preparation, characterization and in vivo observation of phospholipid-based gas-filled microbubbles containing hirudin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Ultrasound, microbubbles and the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Focused ultrasound for blood-brain disruption and delivery of therapeutic molecules into the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Histologic effects of high intensity pulsed ultrasound exposure with subharmonic emission in rabbit brain in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison®)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Observation on the integrity of the blood-brain barrier after microbubble destruction by diagnostic transcranial color-coded sonography

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

MRI investigation of the threshold for thermally induced blood-brain barrier disruption and brain tissue damage in the rabbit brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

A numerical study of transcranial focused ultrasound beam propagation at low frequency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Use of ultrasound pulses combined with Definity for targeted blood-brain barrier disruption: a feasibility study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Role of acoustic cavitation in the delivery and monitoring of cancer treatment by high-intensity focused ultrasound (HIFU).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Phagocytosis of ultrasound contrast agent microbubbles by Kupffer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Imaging tumors with an albumin-binding Fab, a novel tumor-targeting agent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Human pharmacokinetics of a perfluorocarbon ultrasound contrast agent evaluated with gas chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

Safety and efficacy of a new transpulmonary ultrasound contrast agent: Initial multicenter clinical results

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

21 January 2018

The Marangoni Effects

1 reference

https://api.crossref.org/works/10.1517%2F17425247.4.5.475

21 January 2018

Identifiers

DOI

10.1517/17425247.4.5.475

1 reference

17 August 2017

1 reference