(Q36946560)

17 August 2017

1 reference

title

Retinoic acid in the development, regeneration and maintenance of the nervous system (English)

1 reference

17 August 2017

0 references

1 reference

Malcolm Maden

1

1 reference

PubMed ID

17882253

17 August 2017

language of work or name

English

0 references

publication date

1 October 2007

1 reference

Nature Reviews Neuroscience

17 August 2017

1 reference

17 August 2017

8

1 reference

17 August 2017

10

1 reference

17 August 2017

755-765

1 reference

https://scigraph.springernature.com/pub.10.1038/nrn2212

17 August 2017

0 references

cites work

Overview of retinoid metabolism and function

1 reference

A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A

31 March 2020

1 reference

RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development

31 March 2020

1 reference

Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest

31 March 2020

1 reference

Nuclear retinoid receptors and the transcription of retinoid-target genes

31 March 2020

1 reference

Gene expression regulation by retinoic acid

31 March 2020

1 reference

Assigning the positional identity of spinal motor neurons: rostrocaudal patterning of Hox-c expression by FGFs, Gdf11, and retinoids.

31 March 2020

1 reference

Retinoid signalling in the development of the central nervous system

31 March 2020

1 reference

Gene expression and regulation of hindbrain and spinal cord development.

31 March 2020

1 reference

Vitamin A-deficient quail embryos have half a hindbrain and other neural defects.

31 March 2020

1 reference

Retinoic acid and the control of dorsoventral patterning in the avian spinal cord

31 March 2020

1 reference

Generating gradients of retinoic acid in the chick embryo: Cyp26C1 expression and a comparative analysis of the Cyp26 enzymes

31 March 2020

1 reference

Retinoic acid and hindbrain patterning

31 March 2020

1 reference

A Requirement for Retinoic Acid-Mediated Transcriptional Activation in Ventral Neural Patterning and Motor Neuron Specification

31 March 2020

1 reference

The mechanisms of dorsoventral patterning in the vertebrate neural tube

31 March 2020

1 reference

Opposing FGF and retinoid pathways: a signalling switch that controls differentiation and patterning onset in the extending vertebrate body axis

31 March 2020

1 reference

Cell proliferation and DNA replication in the imaginal wing disc of Drosophila melanogaster.

31 March 2020

1 reference

The concentration of retinoic acid determines the differentiated cell types formed by a teratocarcinoma cell line.

31 March 2020

1 reference

Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells

31 March 2020

1 reference

Induction of neural-like cells and acetylcholinesterase activity in cultures of F9 teratocarcinoma treated with retinoic acid and dibutyryl cyclic adenosine monophosphate

31 March 2020

1 reference

Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines

31 March 2020

1 reference

Role and distribution of retinoic acid during CNS development

31 March 2020

1 reference

SHP-1 is involved in neuronal differentiation of P19 embryonic carcinoma cells

31 March 2020

1 reference

Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid

31 March 2020

1 reference

Survival and differentiation of adult rat-derived neural progenitor cells transplanted to the striatum of hemiparkinsonian rats.

31 March 2020

1 reference

Induction of GABAergic phenotype in a neural stem cell line for transplantation in an excitotoxic model of Huntington's disease

31 March 2020

1 reference

Lin(-)CD34(-) bone marrow cells from adult mice can differentiate into neural-like cells.

31 March 2020

1 reference

Transplantation of neural cells derived from retinoic acid-treated cynomolgus monkey embryonic stem cells successfully improved motor function of hemiplegic mice with experimental brain injury

31 March 2020

1 reference

Intraventricular transplantation of embryonic stem cell-derived neural stem cells in intracerebral hemorrhage rats

31 March 2020

1 reference

Peripheral nerve regeneration by transplantation of bone marrow stromal cell-derived Schwann cells in adult rats

31 March 2020

1 reference

Transplantation of motoneuron-enriched neural cells derived from mouse embryonic stem cells improves motor function of hemiplegic mice.

31 March 2020

1 reference

Anatomical and functional recovery by embryonic stem cell-derived neural tissue of a mouse model of brain damage

31 March 2020

1 reference

Somatic motoneurone specification in the hindbrain: the influence of somite-derived signals, retinoic acid and Hoxa3.

31 March 2020

1 reference

Complementary domains of retinoic acid production and degradation in the early chick embryo

31 March 2020

1 reference

Retinoic acid signalling centres in the avian embryo identified by sites of expression of synthesising and catabolising enzymes

31 March 2020

1 reference

Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development.

31 March 2020

1 reference

Patterning of motor neurons by retinoic acid in the chick embryo hindbrain in vitro

31 March 2020

1 reference

The role of vitamin A in the development of the central nervous system.

31 March 2020

1 reference

Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons

31 March 2020

1 reference

Molecular identification of a major retinoic-acid-synthesizing enzyme, a retinaldehyde-specific dehydrogenase

31 March 2020

1 reference

Motor neuron-derived retinoid signaling specifies the subtype identity of spinal motor neurons.

31 March 2020

1 reference

Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons

31 March 2020

1 reference

Retinoid Receptor Signaling in Postmitotic Motor Neurons Regulates Rostrocaudal Positional Identity and Axonal Projection Pattern

31 March 2020

1 reference

Activation of retinoic acid signalling after sciatic nerve injury: up-regulation of cellular retinoid binding proteins

31 March 2020

1 reference

Interactions between retinoic acid, nerve growth factor and sonic hedgehog signalling pathways in neurite outgrowth.

31 March 2020

1 reference

Disruption of the retinoid signalling pathway causes a deposition of amyloid beta in the adult rat brain

31 March 2020

1 reference

Nerve growth factor acts via retinoic acid synthesis to stimulate neurite outgrowth

31 March 2020

1 reference

Regulation of retinoic acid receptors alpha, beta and retinoid X receptor alpha after sciatic nerve injury

31 March 2020

1 reference

Effects of inflammatory cytokines IL-1beta, IL-6, and TNFalpha on the intracellular localization of retinoid receptors in Schwann cells

31 March 2020

1 reference

Retinoic acid receptor beta2 and neurite outgrowth in the adult mouse spinal cord in vitro

31 March 2020

1 reference

Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord

31 March 2020

1 reference

The upregulated expression of sonic hedgehog in motor neurons after rat facial nerve axotomy

31 March 2020

1 reference

New therapeutic target for CNS injury? The role of retinoic acid signaling after nerve lesions.

31 March 2020

1 reference

Effect of retinoic acid on tibial nerve regeneration after anastomosis in rats: histological and functional analyses

31 March 2020

1 reference

Retinoic acid increases tissue and plasma contents of nerve growth factor and prevents neuropathy in diabetic mice.

31 March 2020

1 reference

Characterization of retinaldehyde dehydrogenase-2 induction in NG2-positive glia after spinal cord contusion injury

31 March 2020

1 reference

Retinoic acid synthesis by a population of NG2-positive cells in the injured spinal cord

31 March 2020

1 reference

Distribution of bone morphogenetic protein and bone morphogenetic protein receptor transcripts in the rodent nervous system and up-regulation of bone morphogenetic protein receptor type II in hippocampal dentate gyrus in a rat model of global cerebr

31 March 2020

1 reference

Lentiviral vector expressing retinoic acid receptor beta2 promotes recovery of function after corticospinal tract injury in the adult rat spinal cord.

31 March 2020

1 reference

Differential expression of retinoid receptors in the adult mouse central nervous system.

31 March 2020

1 reference

Working memory deficits in retinoid X receptor gamma-deficient mice

31 March 2020

1 reference

Role of retinoids in the CNS: differential expression of retinoid binding proteins and receptors and evidence for presence of retinoic acid

31 March 2020

1 reference

Retinoic acid signaling at sites of plasticity in the mature central nervous system

31 March 2020

1 reference

Localization of retinaldehyde dehydrogenases and retinoid binding proteins to sustentacular cells, glia, Bowman's gland cells, and stroma: potential sites of retinoic acid synthesis in the postnatal rat olfactory organ

31 March 2020

1 reference

CRBP I and CRABP I localisation during olfactory nerve development.

31 March 2020

1 reference

Plasma delivery of retinoic acid to tissues in the rat.

31 March 2020

1 reference

Retinoic acid is detected at relatively high levels in the CNS of adult rats

31 March 2020

1 reference

Retinoic acid synthesis in normal and Alzheimer diseased brain and human neural cells

31 March 2020

1 reference

Adult rabbit brain synthesizes retinoic acid

31 March 2020

1 reference

Quantification of endogenous retinoic acid in limited biological samples by LC/MS/MS.

31 March 2020

1 reference

Retinoic acid synthesis in the postnatal mouse brain marks distinct developmental stages and functional systems

31 March 2020

1 reference

High levels of a retinoic acid-generating dehydrogenase in the meso-telencephalic dopamine system.

31 March 2020

1 reference

Retinoic acid synthesis for the developing telencephalon

31 March 2020

1 reference

Retinoic acid signaling in the brain marks formation of optic projections, maturation of the dorsal telencephalon, and function of limbic sites

31 March 2020

1 reference

Retinoic acid signaling and function in the adult hippocampus

31 March 2020

1 reference

Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity

31 March 2020

1 reference

13-cis Retinoic acid (accutane) suppresses hippocampal cell survival in mice

31 March 2020

1 reference

Site-specific retinoic acid production in the brain of adult songbirds.

31 March 2020

1 reference

Molecular targets of disulfiram action on song maturation in zebra finches

31 March 2020

1 reference

TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

31 March 2020

1 reference

Vitamin A deficiency leads to increased cell proliferation in olfactory epithelium of mature rats.

31 March 2020

1 reference

Retinoic acid receptor-dependent survival of olfactory sensory neurons in postnatal and adult mice

31 March 2020

1 reference

Retinoic acid enhances the rate of olfactory recovery after olfactory nerve transection.

31 March 2020

1 reference

Vitamin A deficiency and relational memory deficit in adult mice: relationships with changes in brain retinoid signalling

31 March 2020

1 reference

Vitamin A deficiency produces spatial learning and memory impairment in rats.

31 March 2020

1 reference

An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression

31 March 2020

1 reference

13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice

31 March 2020

1 reference

Characterization of the promoter region and flanking sequences of the neuron-specific gene RC3 (neurogranin).

31 March 2020

1 reference

A vitamin A-free diet results in impairment of the rat hippocampal somatostatinergic system.

31 March 2020

1 reference

Coordinated up-regulation of choline acetyltransferase and vesicular acetylcholine transporter gene expression by the retinoic acid receptor alpha, cAMP, and leukemia inhibitory factor/ciliary neurotrophic factor signaling pathways in a murine septa

31 March 2020

1 reference

A synthetic retinoid Am80 (tamibarotene) rescues the memory deficit caused by scopolamine in a passive avoidance paradigm.

31 March 2020

1 reference

Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family.

31 March 2020

1 reference

Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.

31 March 2020

1 reference

Dopamine neuron agenesis in Nurr1-deficient mice

31 March 2020

1 reference

Dystonia and akinesia due to pallidoputaminal lesions after disulfiram intoxication

31 March 2020

1 reference

Lesions of basal ganglia due to disulfiram neurotoxicity

31 March 2020

1 reference

Ethanol inhibition of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome

31 March 2020

1 reference

Retinoic acid enhances neuronal proliferation and astroglial differentiation in cultures of CNS stem cell-derived precursors

31 March 2020

1 reference

Retinoic acid regulates postnatal neurogenesis in the murine subventricular zone-olfactory bulb pathway

31 March 2020

1 reference

In vivo regulation of precursor cells in the subventricular zone of adult rat brain by thyroid hormone and retinoids

31 March 2020

1 reference

Absence of retinoids can induce motoneuron disease in the adult rat and a retinoid defect is present in motoneuron disease patients

31 March 2020

1 reference

Triiodothyronine administration reverses vitamin A deficiency-related hypo-expression of retinoic acid and triiodothyronine nuclear receptors and of neurogranin in rat brain.

31 March 2020

1 reference

31 March 2020

1 reference

Early lesions of vitamin a deficiency

31 March 2020

1 reference

Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays

31 March 2020

1 reference

Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis

31 March 2020

1 reference

Serum levels of beta-carotene, alpha-carotene, and vitamin A in patients with amyotrophic lateral sclerosis.

31 March 2020

1 reference

Impaired extrapyramidal function caused by the targeted disruption of retinoid X receptor RXRgamma1 isoform

31 March 2020

1 reference

Retinoic acid normalizes nuclear receptor mediated hypo-expression of proteins involved in beta-amyloid deposits in the cerebral cortex of vitamin A deprived rats

31 March 2020

1 reference

Retinoid receptors, transporters, and metabolizers as therapeutic targets in late onset Alzheimer disease

31 March 2020

1 reference

Immunodetection of protein composition in cerebral amyloid extracts in Alzheimer's disease: enrichment of retinol-binding protein.

31 March 2020

1 reference

Presenilin 2 expression in neuronal cells: induction during differentiation of embryonic carcinoma cells.

31 March 2020

1 reference

Contrasting role of presenilin-1 and presenilin-2 in neuronal differentiation in vitro.

31 March 2020

1 reference

Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1.

31 March 2020

1 reference

Upregulation of amyloid precursor protein gene promoter in rat primary hippocampal neurons by phorbol ester, IL-1 and retinoic acid, but not by reactive oxygen species.

31 March 2020

1 reference

Altered levels and splicing of the amyloid precursor protein in the adult rat hippocampus after treatment with DMSO or retinoic acid.

31 March 2020

1 reference

Alpha-secretase activation--an approach to Alzheimer's disease therapy

31 March 2020

1 reference

Genomic structure and functional characterization of the human ADAM10 promoter

31 March 2020

1 reference

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

31 March 2020

1 reference

Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor.

31 March 2020

1 reference

Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro

31 March 2020

1 reference

Retinoic acid isomers protect hippocampal neurons from amyloid-beta induced neurodegeneration

31 March 2020

1 reference

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

31 March 2020

1 reference

Amyloid beta-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain.

31 March 2020

1 reference

Regulation of acetylcholinesterase expression during neuronal differentiation

31 March 2020

1 reference

Characterization of the cholinergic neuronal differentiation of the human neuroblastoma cell line LA-N-5 after treatment with retinoic acid

31 March 2020

1 reference

Cholinergic properties of neurons differentiated from an embryonal carcinoma cell-line (P19).

31 March 2020

1 reference

Regulation of acetylcholinesterase activity by retinoic acid in a human neuroblastoma cell line

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRN2212

1 reference

17 August 2017

1 reference

PubMed ID

17882253