(Q36948400)

17 August 2017

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title

Genotoxicity of poorly soluble particles (English)

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17 August 2017

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Roel P F Schins

1

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17 August 2017

Ad M Knaapen

series ordinal

2

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17 August 2017

publication date

1 January 2007

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17 August 2017

published in

Inhalation Toxicology

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17 August 2017

volume

19 Suppl 1

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17 August 2017

page(s)

189-198

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The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence.

21 January 2018

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Blocking neutrophil influx reduces DNA damage in hyperoxia-exposed newborn rat lung

21 January 2018

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Induction of CYP1A1 in rat lung cells following in vivo and in vitro exposure to quartz.

21 January 2018

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Inhaled particles and lung cancer, part B: paradigms and risk assessment

21 January 2018

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Formation of PAH-DNA adducts after in vivo and vitro exposure of rats and lung cells to different commercial carbon blacks.

21 January 2018

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Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air

21 January 2018

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Enhancement of nitric oxide production by pulmonary cells following silica exposure

21 January 2018

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Participation of nitric oxide and iron in the oxidation of DNA in asbestos-treated human lung epithelial cells

21 January 2018

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Formation of nucleoplasmic protein aggregates impairs nuclear function in response to SiO2 nanoparticles

21 January 2018

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Role of free radicals in the toxicity of airborne fine particulate matter

21 January 2018

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Silica-induced generation of extracellular factor(s) increases reactive oxygen species in human bronchial epithelial cells

21 January 2018

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Genotoxic effects of carbon black particles, diesel exhaust particles, and urban air particulates and their extracts on a human alveolar epithelial cell line (A549) and a human monocytic cell line (THP-1).

21 January 2018

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Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells

21 January 2018

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Inflammatory and genotoxic effects of diesel particles in vitro and in vivo

21 January 2018

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The epigenetic progenitor origin of human cancer

21 January 2018

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Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis

21 January 2018

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Formation of DNA adducts in rat lung following chronic inhalation of diesel emissions, carbon black and titanium dioxide particles.

21 January 2018

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Formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine in rat lung DNA following subchronic inhalation of carbon black

21 January 2018

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Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells

21 January 2018

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Molecular mechanisms of mammalian global genome nucleotide excision repair.

21 January 2018

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Toxicity of fibers and particles report of the workshop held in Munich, Germany, October 26-27, 2000

21 January 2018

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Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells

21 January 2018

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The effect of iron binding on the ability of crocidolite asbestos to catalyze DNA single-strand breaks.

21 January 2018

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Role of DNA repair in particle- and fiber-induced lung injury

21 January 2018

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Mutagenicity of arsenic in mammalian cells: role of reactive oxygen species

21 January 2018

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Fibre-induced lipid peroxidation leads to DNA adduct formation in Salmonella typhimurium TA104 and rat lung fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1080%2F08958370701496202

Mechanisms of fiber-induced genotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

The role of metals in site-specific DNA damage with reference to carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Genotoxicity of diesel-exhaust particles dispersed in simulated pulmonary surfactant

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Arsenic induces oxidative DNA damage in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

DNA damage in lung epithelial cells isolated from rats exposed to quartz: role of surface reactivity and neutrophilic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Mechanisms of neutrophil-induced DNA damage in respiratory tract epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F08958370701496202

Inhaled particles and lung cancer. Part A: Mechanisms

21 January 2018

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https://api.crossref.org/works/10.1080%2F08958370701496202

Neutrophils and respiratory tract DNA damage and mutagenesis: a review

21 January 2018

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https://api.crossref.org/works/10.1080%2F08958370701496202

Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage

21 January 2018

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https://api.crossref.org/works/10.1080%2F08958370701496202

Micronucleus formation in V79 cells treated with respirable silica dispersed in medium and in simulated pulmonary surfactant

21 January 2018

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https://api.crossref.org/works/10.1080%2F08958370701496202

Nature and nurture - lessons from chemical carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1080%2F08958370701496202

Oxyradicals and DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Silica-induced micronuclei and chromosomal aberrations in Chinese hamster lung (V79) and human lung (Hel 299) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Polycyclic aromatic hydrocarbon (PAH) o-quinones produced by the aldo-keto-reductases (AKRs) generate abasic sites, oxidized pyrimidines, and 8-oxo-dGuo via reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Air pollution particles mediated oxidative DNA base damage in a cell free system and in human airway epithelial cells in relation to particulate metal content and bioreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Why is the hydroxyl radical the only radical that commonly adds to DNA? Hypothesis: it has a rare combination of high electrophilicity, high thermochemical reactivity, and a mode of production that can occur near DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Evidence that ultrafine titanium dioxide induces micronuclei and apoptosis in Syrian hamster embryo fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Investigations on the inflammatory and genotoxic lung effects of two types of titanium dioxide: untreated and surface treated

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Oxidative DNA damage and defence gene expression in the mouse lung after short-term exposure to diesel exhaust particles by inhalation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Increase in mutation frequency in lung of Big Blue rat by exposure to diesel exhaust.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Surface modification of quartz inhibits toxicity, particle uptake, and oxidative DNA damage in human lung epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Mechanisms of genotoxicity of particles and fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Quartz exposure of the rat lung leads to a linear dose response in inflammation but not in oxidative DNA damage and mutagenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Silica radical-induced DNA damage and lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Quinoid redox cycling as a mechanism for sustained free radical generation by inhaled airborne particulate matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Genotoxicity of urban air pollutants in the Czech Republic. Part II. DNA adduct formation in mammalian cells by extractable organic matter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Arsenic inhibits the repair of DNA damage induced by benzo(a)pyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

In vitro effects of coal fly ashes: hydroxyl radical generation, iron release, and DNA damage and toxicity in rat lung epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Cancer genes and the pathways they control

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Identification of DNA damage as a result of exposure of rats to diesel engine exhaust

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

Detection of mineral-dust-induced DNA damage in two mammalian cell lines using the alkaline single cell gel/comet assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

The Pulmonary Toxicology of Ultrafine Particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08958370701496202

10.1080/08958370701496202

21 January 2018

Identifiers

DOI

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17 August 2017

1 reference