(Q36949936)

17 August 2017

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title

Organ selectivity in metastasis: regulation by chemokines and their receptors (English)

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17 August 2017

Adit Ben-Baruch

1

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17 August 2017

21 September 2007

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Clinical & Experimental Metastasis

17 August 2017

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17 August 2017

25

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17 August 2017

345-356

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17 August 2017

4

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https://scigraph.springernature.com/pub.10.1007/s10585-007-9097-3

17 August 2017

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cites work

Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC)

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https://api.crossref.org/works/10.1007%2FS10585-007-9097-3

Transendothelial migration of two metastatic breast carcinoma cells depend on the SDF-lalpha-CXCR4 complexes.

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12 December 2020

The chemokine SDF1a coordinates tissue migration through the spatially restricted activation of Cxcr7 and Cxcr4b

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12 December 2020

Expression of CC chemokine receptor-7 and regional lymph node metastasis of B16 murine melanoma

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12 December 2020

SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers

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12 December 2020

CXCR4 regulates growth of both primary and metastatic breast cancer

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12 December 2020

Mechanism of human stem cell migration and repopulation of NOD/SCID and B2mnull NOD/SCID mice. The role of SDF-1/CXCR4 interactions

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12 December 2020

Multiple chemotactic factors: fine control or redundancy?

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12 December 2020

The pivotal role of CXCL12 (SDF-1)/CXCR4 axis in bone metastasis

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12 December 2020

The significance of cancer cell expression of the chemokine receptor CXCR4.

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12 December 2020

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12 December 2020

Inflammation-associated immune suppression in cancer: the roles played by cytokines, chemokines and additional mediators

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12 December 2020

The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study.

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12 December 2020

Genetic manipulation of stromal cell-derived factor-1 attests the pivotal role of the autocrine SDF-1-CXCR4 pathway in the aggressiveness of breast cancer cells.

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12 December 2020

Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion.

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12 December 2020

Expression of chemokine receptors predicts the site of metastatic relapse in patients with axillary node positive primary breast cancer.

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12 December 2020

Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

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12 December 2020

Immune Evasion by Murine Melanoma Mediated through CC Chemokine Receptor-10

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12 December 2020

Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer

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12 December 2020

Chemokines: signal lamps for trafficking of T and B cells for development and effector function.

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12 December 2020

A proposed mechanism for the protective effect of dioxin against breast cancer

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12 December 2020

Chemokines: agents for the immunotherapy of cancer?

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12 December 2020

The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis.

1 reference

12 December 2020

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

1 reference

12 December 2020

CXC chemokines in angiogenesis of cancer

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12 December 2020

Recombination of CXCR4, VEGF, and MMP-9 predicting lymph node metastasis in human breast cancer

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12 December 2020

The role of chemokine receptors in primary, effector, and memory immune responses

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12 December 2020

The tumor microenvironment in the post-PAGET era.

1 reference

12 December 2020

Critical determinants of metastasis

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12 December 2020

Cancer CXC chemokine networks and tumour angiogenesis

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12 December 2020

Potential role of CCL27 and CCR10 expression in melanoma progression and immune escape

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12 December 2020

CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells

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12 December 2020

Stromal cell-derived factor-1 and CXCR4 receptor interaction in tumor growth and metastasis of breast cancer.

1 reference

12 December 2020

Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses

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12 December 2020

Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4.

1 reference

12 December 2020

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

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12 December 2020

The chemokine and chemokine receptor superfamilies and their molecular evolution

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12 December 2020

Carboxyl-terminal Src kinase homologous kinase negatively regulates the chemokine receptor CXCR4 through YY1 and impairs CXCR4/CXCL12 (SDF-1alpha)-mediated breast cancer cell migration

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12 December 2020

CCL21 promotes the migration and adhesion of highly lymph node metastatic human non-small cell lung cancer Lu-99 in vitro.

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12 December 2020

Oral and oropharyngeal squamous cell carcinomas expressing CCR7 have poor prognoses

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12 December 2020

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

1 reference

12 December 2020

Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells

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12 December 2020

CXCR4 is expressed in ductal carcinoma in situ of the breast and in atypical ductal hyperplasia.

1 reference

12 December 2020

Tannic acid is an inhibitor of CXCL12 (SDF-1alpha)/CXCR4 with antiangiogenic activity

1 reference

12 December 2020

Expression of CXCR4 is associated with axillary lymph node status in patients with early breast cancer

1 reference

12 December 2020

Expression and function of the chemokine receptor CCR7 in thyroid carcinomas.

1 reference

12 December 2020

Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro

1 reference

12 December 2020

Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells

1 reference

12 December 2020

A role for endothelin-2 and its receptors in breast tumor cell invasion

1 reference

12 December 2020

Enhancing effect of platelet-derived microvesicles on the invasive potential of breast cancer cells

1 reference

12 December 2020

A chemokine, SDF-1/PBSF, and its receptor, CXC chemokine receptor 4, as mediators of hematopoiesis.

1 reference

12 December 2020

The organ microenvironment and cancer metastasis

1 reference

12 December 2020

A multigenic program mediating breast cancer metastasis to bone

1 reference

12 December 2020

Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype.

1 reference

12 December 2020

Silencing of CXCR4 blocks breast cancer metastasis

1 reference

12 December 2020

An attractive force in metastasis

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12 December 2020

Therapeutic intervention of experimental breast cancer bone metastasis by indole-3-carbinol in SCID-human mouse model

1 reference

12 December 2020

Functions of CXCL12 and CXCR4 in breast cancer

1 reference

12 December 2020

The influence of the microenvironment on the malignant phenotype

1 reference

12 December 2020

HGF induces CXCR4 and CXCL12-mediated tumor invasion through Ets1 and NF-kappaB.

1 reference

12 December 2020

CXCL-12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation

1 reference

12 December 2020

The chemokine system: tuning and shaping by regulation of receptor expression and coupling in polarized responses.

1 reference

12 December 2020

Involvement of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1alpha in breast cancer cell migration through human brain microvascular endothelial cells

1 reference

12 December 2020

Lower expression of CXCR4 in lymph node metastases than in primary breast cancers: potential regulation by ligand-dependent degradation and HIF-1alpha

1 reference

12 December 2020

CXC chemokines in angiogenesis.

1 reference

12 December 2020

Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors

1 reference

12 December 2020

CCL21 chemokine regulates chemokine receptor CCR7 bearing malignant melanoma cells.

1 reference

12 December 2020

Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system

1 reference

12 December 2020

Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells

1 reference

12 December 2020

Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes

1 reference

12 December 2020

The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1.

1 reference

12 December 2020

Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system

1 reference

12 December 2020

T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer

1 reference

12 December 2020

Chemokine mediated control of dendritic cell migration and function.

1 reference

12 December 2020

Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells

1 reference

12 December 2020

The CXCL12-CXCR4 chemotactic pathway as a target of adjuvant breast cancer therapies

1 reference

12 December 2020

Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer

1 reference

12 December 2020

Increased chemokine receptor CCR7/EBI1 expression enhances the infiltration of lymphoid organs by adult T-cell leukemia cells

1 reference

12 December 2020

The microenvironment of the tumour-host interface

1 reference

12 December 2020

Involvement of chemokine receptors in breast cancer metastasis

1 reference

12 December 2020

Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma

1 reference

12 December 2020

Chemokine receptors and melanoma metastasis

1 reference

12 December 2020

Involvement of chemokine receptors in organ-specific metastasis

1 reference

12 December 2020

Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma

1 reference

12 December 2020

Prediction of lymph node metastasis in colorectal carcinoma by expressionof chemokine receptor CCR7

1 reference

12 December 2020

Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells

1 reference

12 December 2020

Regulation of the trafficking of tumour-infiltrating dendritic cells by chemokines

1 reference

12 December 2020

Leukocyte migration: scent of the T zone

1 reference

12 December 2020

CXCR4 knockdown by small interfering RNA abrogates breast tumor growth in vivo

1 reference

12 December 2020

CCL2 (Monocyte Chemoattractant Protein-1) in cancer bone metastases

1 reference

12 December 2020

CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells.

1 reference

12 December 2020

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1 reference

12 December 2020

Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells.

1 reference

12 December 2020

Liver metastasis of cancer facilitated by chemokine receptor CCR6.

1 reference

12 December 2020

Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4.

1 reference

12 December 2020

The multifaceted roles of chemokines in malignancy

1 reference

12 December 2020

CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells

1 reference

12 December 2020

Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo

1 reference

12 December 2020

Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease.

1 reference

12 December 2020

Chemokine receptor CXCR4 expression in breast cancer as a potential predictive marker of isolated tumor cells in bone marrow

1 reference

12 December 2020

Deletion of the COOH-terminal domain of CXC chemokine receptor 4 leads to the down-regulation of cell-to-cell contact, enhanced motility and proliferation in breast carcinoma cells

1 reference

12 December 2020

Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis

1 reference

12 December 2020

International union of pharmacology. XXII. Nomenclature for chemokine receptors

1 reference

12 December 2020

Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma

1 reference

12 December 2020

Cancer and the chemokine network

1 reference

12 December 2020

New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects

1 reference

12 December 2020

Chemokine/chemokine receptor nomenclature

1 reference

12 December 2020

Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling

1 reference

12 December 2020

Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter

1 reference

12 December 2020

Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells.

1 reference

12 December 2020

CCR7 and CXCR4 as novel biomarkers predicting axillary lymph node metastasis in T1 breast cancer

1 reference

12 December 2020

Hepatocyte growth factor enhances CXCR4 expression favoring breast cancer cell invasiveness.

1 reference

12 December 2020

Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumor cells

1 reference

12 December 2020

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

1 reference

12 December 2020

The chemokine receptor CCR7 and alpha4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes

1 reference

12 December 2020

A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes

1 reference

12 December 2020

p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts

1 reference

12 December 2020

The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer

1 reference

12 December 2020

Chemokines: a new classification system and their role in immunity

1 reference

12 December 2020

CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

1 reference

12 December 2020

Chemokines in neoplastic progression

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12 December 2020

CCL2 (monocyte chemoattractant protein-1) and cancer

1 reference

12 December 2020

Presence and functions of immune components in the tumor microenvironment

1 reference

12 December 2020

Chemokines, chemokine receptors, and cancer metastasis

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12 December 2020

Endothelins induce CCR7 expression by breast tumor cells via endothelin receptor A and hypoxia-inducible factor-1

1 reference

12 December 2020

The chemokine system: redundancy for robust outputs

1 reference

12 December 2020

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

1 reference

12 December 2020

Expression of growth factor and chemokine receptors: new insights in the biology of inflammatory breast cancer

1 reference

12 December 2020

The p160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine/paracrine activity of SDF-1alpha/CXCL12.

1 reference

12 December 2020

Expression of vascular endothelial growth factor C and chemokine receptor CCR7 in gastric carcinoma and their values in predicting lymph node metastasis.

1 reference

12 December 2020

10.1007/S10585-007-9097-3

Identifiers

DOI

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17 August 2017

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PubMed ID

17891505