(Q36952835)

17 August 2017

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title

Modulation of host metabolism as a target of new antivirals (English)

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17 August 2017

Masanori Ikeda

1

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17 August 2017

Nobuyuki Kato

series ordinal

2

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17 August 2017

language of work or name

English

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publication date

11 August 2007

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Advanced Drug Delivery Reviews

17 August 2017

published in

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17 August 2017

volume

59

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17 August 2017

issue

12

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17 August 2017

page(s)

1277-1289

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Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

17 August 2017

cites work

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12 December 2020

Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus

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12 December 2020

Effect of alpha interferon on the hepatitis C virus replicon

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12 December 2020

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

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12 December 2020

Hepatitis C Virus RNA Replication Occurs on a Detergent-Resistant Membrane That Cofractionates with Caveolin-2

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12 December 2020

Mechanism of action of interferon and ribavirin in treatment of hepatitis C

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12 December 2020

Treatment of chronic non-A,non-B hepatitis with recombinant human alpha interferon. A preliminary report

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12 December 2020

The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase

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12 December 2020

Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a phase Ib, placebo-controlled, randomized study

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12 December 2020

Comparative inhibitory effects of various nucleoside and nonnucleoside analogues on replication of influenza virus types A and B in vitro and in ovo.

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12 December 2020

Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins

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12 December 2020

Pleiotropic effects of statins

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12 December 2020

Structure and function of the hepatitis C virus NS3-NS4A serine proteinase.

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12 December 2020

Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model

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12 December 2020

Interference of hepatitis C virus RNA replication by short interfering RNAs

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12 December 2020

Genetic variation and dynamics of hepatitis C virus replicons in long-term cell culture

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12 December 2020

The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.

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12 December 2020

Efficient Replication of Hepatitis C Virus Genotype 1a RNAs in Cell Culture

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12 December 2020

Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90

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12 December 2020

In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease

1 reference

12 December 2020

Inhibition of bovine viral diarrhea virus (BVDV) by mizoribine: synergistic effect of combination with interferon-alpha

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12 December 2020

Mycophenolic acid, an immunosuppressive agent, inhibits HBV replication in vitro

1 reference

12 December 2020

S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro

1 reference

12 December 2020

Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication

1 reference

12 December 2020

Mycophenolic acid inhibits dengue virus infection by preventing replication of viral RNA.

1 reference

12 December 2020

Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids

1 reference

12 December 2020

Small Interfering RNA Targeted to Hepatitis C Virus 5' Nontranslated Region Exerts Potent Antiviral Effect

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12 December 2020

Ability of prolonged interferon treatment to suppress relapse after cessation of therapy in patients with chronic hepatitis C: a multicenter randomized controlled trial.

1 reference

12 December 2020

Hepatitis C virus NS5B delays cell cycle progression by inducing interferon-beta via Toll-like receptor 3 signaling pathway without replicating viral genomes

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12 December 2020

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

1 reference

12 December 2020

Interferon combined with cyclosporine treatment as an effective countermeasure against hepatitis C virus recurrence in liver transplant patients with end-stage hepatitis C virus related disease

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12 December 2020

Statin compounds reduce human immunodeficiency virus type 1 replication by preventing the interaction between virion-associated host intercellular adhesion molecule 1 and its natural cell surface ligand LFA-1.

1 reference

12 December 2020

Establishment of hepatitis C virus replicon cell lines possessing interferon-resistant phenotype

1 reference

12 December 2020

Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system.

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12 December 2020

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

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12 December 2020

Host cell factor requirement for hepatitis C virus enzyme maturation

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12 December 2020

Oral prostaglandin (PGE2) therapy for chronic viral hepatitis B and C.

1 reference

12 December 2020

Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes

1 reference

12 December 2020

Transmission of hepatitis C virus infection to tree shrews

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12 December 2020

Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes

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12 December 2020

Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bio

1 reference

12 December 2020

Antiviral activity of lovastatin against respiratory syncytial virus in vivo and in vitro

1 reference

12 December 2020

A critical role for the chimpanzee model in the study of hepatitis C.

1 reference

12 December 2020

Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon

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12 December 2020

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

1 reference

12 December 2020

Antiviral action of ribavirin in chronic hepatitis C.

1 reference

12 December 2020

Mycophenolic acid inhibits avian reovirus replication

1 reference

12 December 2020

The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus

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12 December 2020

Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication

1 reference

12 December 2020

Toward a surrogate model for hepatitis C virus: An infectious molecular clone of the GB virus-B hepatitis agent.

1 reference

12 December 2020

Antiviral therapy for chronic hepatitis C: past, present, and future

1 reference

12 December 2020

Interferon resistance of hepatitis C virus replicon-harbouring cells is caused by functional disruption of type I interferon receptors

1 reference

12 December 2020

Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(i)-poly(c), tumor necrosis factor alpha, and ribavirin in hepatitis C virus subgenomic replicons

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12 December 2020

Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811.

1 reference

12 December 2020

Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium

1 reference

12 December 2020

Current therapy and new molecular approaches to antiviral treatment and prevention of hepatitis C.

1 reference

12 December 2020

NIM811, a Cyclophilin Inhibitor, Exhibits Potent In Vitro Activity against Hepatitis C Virus Alone or in Combination with Alpha Interferon

1 reference

12 December 2020

Recent advances in the analysis of HCV NS5B RNA-dependent RNA polymerase

1 reference

12 December 2020

Prevalence of antibody against non-A, non-B hepatitis virus in Japanese patients with hepatocellular carcinoma

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12 December 2020

Hepatitis C virus proteins exhibit conflicting effects on the interferon system in human hepatocyte cells

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12 December 2020

Differential activation of interferon-inducible genes by hepatitis C virus core protein mediated by the interferon stimulated response element.

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12 December 2020

Different anti-HCV profiles of statins and their potential for combination therapy with interferon

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12 December 2020

Hepatitis C virus replication in mice with chimeric human livers

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12 December 2020

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

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12 December 2020

Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity

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12 December 2020

Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon

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12 December 2020

Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon- alpha

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12 December 2020

Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication

1 reference

12 December 2020

Host sphingolipid biosynthesis as a target for hepatitis C virus therapy

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12 December 2020

Epigenetic silencing of interferon-inducible genes is implicated in interferon resistance of hepatitis C virus replicon-harboring cells

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12 December 2020

Anti-HCV activities of selective polyunsaturated fatty acids

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12 December 2020

Complete replication of hepatitis C virus in cell culture

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12 December 2020

Combined interferon alpha2b and cyclosporin A in the treatment of chronic hepatitis C: controlled trial

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12 December 2020

Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation

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12 December 2020

Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells

1 reference

12 December 2020

VX-950, a Novel Hepatitis C Virus (HCV) NS3-4A Protease Inhibitor, Exhibits Potent Antiviral Activities in HCV Replicon Cells

1 reference

12 December 2020

Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts

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12 December 2020

Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells

1 reference

12 December 2020

Mizoribine and mycophenolate mofetil

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12 December 2020

Mycophenolic acid inhibits hepatitis C virus replication and acts in synergy with cyclosporin A and interferon-alpha.

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12 December 2020

Comprehensive Analysis of the Effects of Ordinary Nutrients on Hepatitis C Virus RNA Replication in Cell Culture

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12 December 2020

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

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12 December 2020

cDNA microarray analysis to compare HCV subgenomic replicon cells with their cured cells

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12 December 2020

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

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12 December 2020

Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice

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12 December 2020

Molecular virology of hepatitis C virus

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12 December 2020

Antiviral effect of alpha-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles.

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12 December 2020

Identification of active antiviral compounds against a New York isolate of West Nile virus

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12 December 2020

Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.

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12 December 2020

Development of a GB virus B marmoset model and its validation with a novel series of hepatitis C virus NS3 protease inhibitors

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12 December 2020

Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs

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12 December 2020

Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

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12 December 2020

Glycosylation of hepatitis C virus envelope proteins

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12 December 2020

Establishment of a hepatitis C virus subgenomic replicon derived from human hepatocytes infected in vitro

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12 December 2020

Specific inhibition of hepatitis C virus replication by cyclosporin A.

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12 December 2020

Robust hepatitis C virus infection in vitro

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12 December 2020

Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha

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12 December 2020

Efficient initiation of HCV RNA replication in cell culture

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12 December 2020

Cell culture-adaptive NS3 mutations required for the robust replication of genome-length hepatitis C virus RNA.

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12 December 2020

RNA virus error catastrophe: direct molecular test by using ribavirin

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12 December 2020

Subgenomic replicon derived from a cell line infected with the hepatitis C virus

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12 December 2020

Hydroxymethyl-glutaryl coenzyme a reductase inhibition limits cytomegalovirus infection in human endothelial cells

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12 December 2020

The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro

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12 December 2020

Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs

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12 December 2020

Persistent and transient replication of full-length hepatitis C virus genomes in cell culture

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12 December 2020

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

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12 December 2020

Diverse Effects of Cyclosporine on Hepatitis C Virus Strain Replication

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12 December 2020

Inhibition of dengue virus replication by mycophenolic acid and ribavirin

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12 December 2020

10.1016/J.ADDR.2007.03.021

Identifiers

DOI

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17 August 2017

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