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TIM-1 and TIM-3 proteins in immune regulation.
scientific article published on 15 August 2008
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Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
review article
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Europe PubMed Central
title
TIM-1 and TIM-3 proteins in immune regulation
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
author
Lawrence P. Kane
series ordinal
3
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Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
author name string
Ee Wern Su
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
Jean Y Lin
series ordinal
2
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stated in
Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
publication date
15 August 2008
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Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
published in
Cytokine
1 reference
stated in
Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
volume
44
1 reference
stated in
Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
page(s)
9-13
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Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
cites work
T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase
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PubMed Central
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Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells
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TIM-4 expressed on APCs induces T cell expansion and survival
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PubMed Central
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Lack of TIM-3 immunoregulation in multiple sclerosis
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The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model
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Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds
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TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.
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Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice
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Expression of human TIM-1 and TIM-3 on lymphocytes from systemic lupus erythematosus patients
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29 September 2017
Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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Identification of Tim4 as a phosphatidylserine receptor
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
TIM family proteins and autoimmunity.
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29 September 2017
TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function
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PubMed Central
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29 September 2017
Evidence for carbohydrate recognition and homotypic and heterotypic binding by the TIM family
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PubMed Central
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29 September 2017
T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family
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PubMed Central
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29 September 2017
Immune regulation by the TIM gene family
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PubMed Central
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29 September 2017
TIM-1 regulates macrophage cytokine production and B7 family member expression
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PubMed Central
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29 September 2017
A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
TIM family of genes in immunity and tolerance
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
Dysregulated T cell expression of TIM3 in multiple sclerosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
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29 September 2017
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
The TIM gene family regulates autoimmune and allergic diseases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
TIM-1 induces T cell activation and inhibits the development of peripheral tolerance
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
Hepatitis A virus receptor blocks cell differentiation and is overexpressed in clear cell renal cell carcinoma
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29 September 2017
TIM-1, a novel allergy and asthma susceptibility gene
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29 September 2017
The association of the exon 4 variations of Tim-1 gene with allergic diseases in a Korean population
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
Molecular variations in the promoter and coding regions of human Tim-1 gene and their association in Koreans with asthma
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
29 September 2017
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
Immunology: hepatitis A virus link to atopic disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
The TIM gene family: emerging roles in immunity and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
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29 September 2017
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
29 September 2017
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
29 September 2017
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
29 September 2017
The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
29 September 2017
The Cys-rich region of hepatitis A virus cellular receptor 1 is required for binding of hepatitis A virus and protective monoclonal antibody 190/4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
29 September 2017
Identification of a surface glycoprotein on African green monkey kidney cells as a receptor for hepatitis A virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
29 September 2017
The Tim-3 ligand galectin-9 negatively regulates CD8+ alloreactive T cell and prolongs survival of skin graft
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
4 September 2018
Genetic association studies between the T cell immunoglobulin mucin (TIM) gene locus and childhood atopic dermatitis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
4 September 2018
TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
4 September 2018
The polymorphisms of Tim-1 promoter region are associated with rheumatoid arthritis in a Korean population.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
4 September 2018
Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
4 September 2018
Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
20 October 2018
Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574986
retrieved
20 October 2018
Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18706830
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18706830
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cutting edge: cross-regulation by TLR4 and T cell Ig mucin-3 determines sex differences in inflammatory heart disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18706830
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression of T-cell immunoglobulin- and mucin-domain-containing molecule-1 (TIM-1) is increased in a mouse model of asthma and relationship to GATA-3
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18706830
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18706830
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CYTO.2008.06.013
1 reference
stated in
Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
PMC publication ID
2574986
1 reference
stated in
Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
PubMed publication ID
18706830
1 reference
stated in
Europe PubMed Central
PMC publication ID
2574986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18706830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
ResearchGate publication ID
23174381
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