(Q36956331)

17 August 2017

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title

Mechanism-based pharmacokinetic-pharmacodynamic modeling of antimicrobial drug effects (English)

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17 August 2017

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David Czock

1

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PubMed ID

17906920

17 August 2017

Frieder Keller

series ordinal

2

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17 August 2017

29 September 2007

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Journal of Pharmacokinetics and Pharmacodynamics

17 August 2017

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17 August 2017

34

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17 August 2017

6

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17 August 2017

727-751

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https://scigraph.springernature.com/pub.10.1007/s10928-007-9069-x

17 August 2017

0 references

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Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

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https://api.crossref.org/works/10.1007%2FS10928-007-9069-X

Pharmacokinetic and pharmacodynamic approach for comparing two therapeutic regimens using amikacin

21 January 2018

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Mechanism-based pharmacodynamic models of fluoroquinolone resistance in Staphylococcus aureus

21 January 2018

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12 December 2020

Antimicrobials: Modes of Action and Mechanisms of Resistance

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12 December 2020

Modelling time-kill studies to discern the pharmacodynamics of meropenem

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Application of logistic growth model to pharmacodynamic analysis of in vitro bactericidal kinetics.

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Use of pharmacodynamic indices to predict efficacy of combination therapy in vivo.

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A combined in vivo pharmacokinetic-in vitro pharmacodynamic approach to simulate target site pharmacodynamics of antibiotics in humans

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12 December 2020

Pharmacokinetic-pharmacodynamic modeling of activity of ceftazidime during continuous and intermittent infusion.

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12 December 2020

Relationship between minimum inhibitory concentration and stationary concentration revisited: growth rates and minimum bactericidal concentrations

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12 December 2020

Pharmacodynamics of Chemotherapeutic Effects: Dose-Time-Response Relationships for Phase-Nonspecific Agents

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12 December 2020

Mechanism-based pharmacodynamic modeling

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12 December 2020

Pharmacokinetic-pharmacodynamic modelling of the in vitro antiinfective effect of piperacillin-tazobactam combinations

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12 December 2020

Selection of a moxifloxacin dose that suppresses drug resistance in Mycobacterium tuberculosis, by use of an in vitro pharmacodynamic infection model and mathematical modeling

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12 December 2020

Comparative pharmacodynamics of gentamicin against Staphylococcus aureus and Pseudomonas aeruginosa

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12 December 2020

Pharmacodynamic functions: a multiparameter approach to the design of antibiotic treatment regimens

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12 December 2020

Pharmacodynamic modeling of ciprofloxacin resistance in Staphylococcus aureus

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12 December 2020

Novel pharmacokinetic-pharmacodynamic model for prediction of outcomes with an extended-release formulation of ciprofloxacin

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12 December 2020

A pharmacodynamic model for the activity of antibiotics against microorganisms under nonsaturable conditions.

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12 December 2020

Pharmacodynamic modeling of the evolution of levofloxacin resistance in Staphylococcus aureus

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12 December 2020

A concept for pharmacokinetic-pharmacodynamic dosage adjustment in renal impairment: the case of aminoglycosides.

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12 December 2020

Pharmacodynamics of the new fluoroquinolone gatifloxacin in murine thigh and lung infection models

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12 December 2020

Pharmacokinetic-pharmacodynamic modelling of the antimalarial activity of mefloquine

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12 December 2020

Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy

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12 December 2020

Impact of tazobactam pharmacokinetics on the antimicrobial effect of piperacillin-tazobactam combinations

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12 December 2020

PK-PD modelling of the effect of cefaclor on four different bacterial strains

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12 December 2020

Pharmacokinetic-pharmacodynamic modelling of antibacterial activity of cefpodoxime and cefixime in in vitro kinetic models

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12 December 2020

Pharmacodynamics of levofloxacin and ciprofloxacin in a murine pneumonia model: peak concentration/MIC versus area under the curve/MIC ratios

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12 December 2020

Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men.

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12 December 2020

Pharmacokinetic/pharmacodynamic (PK/PD) evaluation of a once-daily treatment using ciprofloxacin in an extended-release dosage form

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12 December 2020

Aminoglycoside pharmacokinetics and -dynamics: a nonlinear approach.

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12 December 2020

Dose adjustment of ciprofloxacin in renal failure: reduce the dose or prolong the administration interval?

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12 December 2020

In vivo pharmacodynamic activity of daptomycin

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12 December 2020

Antimicrobial Resistance: Pharmacokinetics‐Pharmacodynamics of Antimicrobial Therapy: It’s Not Just for Mice Anymore

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12 December 2020

Pharmacodynamic dose adjustment in renal failure: importance of the Hill coefficient.

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Pharmacokinetic/pharmacodynamic modeling of in vitro activity of azithromycin against four different bacterial strains

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The crisis of resistance: identifying drug exposures to suppress amplification of resistant mutant subpopulations

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Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments

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Comparative stability studies of antipseudomonal beta-lactams for potential administration through portable elastomeric pumps (home therapy for cystic fibrosis patients) and motor-operated syringes (intensive care units)

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Evaluating ciprofloxacin dosing for Pseudomonas aeruginosa infection by using clinical outcome-based Monte Carlo simulations

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12 December 2020

Some suggestions for measuring predictive performance

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12 December 2020

Pharmacodynamic modeling of bacterial kinetics: beta-lactam antibiotics against Escherichia coli.

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12 December 2020

Pharmacokinetic-pharmacodynamic modeling of the antibiotic effect of piperacillin in vitro

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12 December 2020

Calculating predictive performance: a user's note.

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12 December 2020

Pharmacokinetic/pharmacodynamic modelling of antibacterials in vitro and in vivo using bacterial growth and kill kinetics: the minimum inhibitory concentration versus stationary concentration.

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12 December 2020

Are population pharmacokinetic and/or pharmacodynamic models adequately evaluated? A survey of the literature from 2002 to 2004.

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12 December 2020

Mefloquine pharmacokinetic-pharmacodynamic models: implications for dosing and resistance.

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12 December 2020

A new modeling approach to the effect of antimicrobial agents on heterogeneous microbial populations

1 reference

12 December 2020

The dynamics of drug action on the within-host population growth of infectious agents: melding pharmacokinetics with pathogen population dynamics.

1 reference

12 December 2020

Microbial pharmacodynamics of piperacillin in neutropenic mice of systematic infection due to Pseudomonas aeruginosa

1 reference

12 December 2020

Comparisons between antimicrobial pharmacodynamic indices and bacterial killing as described by using the Zhi model

1 reference

12 December 2020

Diversity of mechanism-based pharmacodynamic models

1 reference

12 December 2020

Kinetics of antimicrobial action

1 reference

12 December 2020

Bacterial-population responses to drug-selective pressure: examination of garenoxacin's effect on Pseudomonas aeruginosa

1 reference

12 December 2020

Studies of antibiotic resistance within the patient, hospitals and the community using simple mathematical models

1 reference

12 December 2020

A pharmacokinetic-pharmacodynamic disease model to predict in vivo antiviral activity of maraviroc

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12 December 2020

Pharmacokinetic/pharmacodynamic evaluation of anti-infective agents

1 reference

12 December 2020

Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: kill curves versus MIC

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12 December 2020

Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.

1 reference

12 December 2020

The population dynamics of antimicrobial chemotherapy.

1 reference

12 December 2020

10.1007/S10928-007-9069-X

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17906920