(Q36967940)

English

Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of Pax3 function.

scientific article published on 26 August 2008

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scholarly article

1 reference

Europe PubMed Central

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13 January 2020

Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of Pax3 function (English)

1 reference

Europe PubMed Central

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13 January 2020

1 reference

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folate deficiency

1 reference

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Valentina Massa

3

1 reference

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13 January 2020

6

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13 January 2020

7

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13 January 2020

Nicholas D.E. Greene

8

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13 January 2020

author name string

Katie A Burren

1

1 reference

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13 January 2020

Dawn Savery

2

1 reference

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13 January 2020

Robert M Kok

4

1 reference

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13 January 2020

John M Scott

5

1 reference

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13 January 2020

language of work or name

1 reference

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publication date

26 August 2008

1 reference

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13 January 2020

Human Molecular Genetics

1 reference

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13 January 2020

17

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13 January 2020

23

1 reference

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13 January 2020

3675-3685

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753144%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Multiple B-vitamin inadequacy amplifies alterations induced by folate depletion in p53 expression and its downstream effector MDM2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Integrity of the methylation cycle is essential for mammalian neural tube closure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Neural tube defects and folate: case far from closed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Neurulation in the cranial region--normal and abnormal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Human neural tube defects: developmental biology, epidemiology, and genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Candidate gene analysis in human neural tube defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Mouse models of neural tube defects: investigating preventive mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

The genetic basis of mammalian neurulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Pax3 and the splotch mutations: structure, function, and relationship to teratogenesis, including gene-chemical interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Folate, homocysteine and neural tube defects: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Folate and vitamin B12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Homocysteine induces congenital defects of the heart and neural tube: effect of folic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Female predisposition to cranial neural tube defects is not because of a difference between the sexes in the rate of embryonic growth or development during neurulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Etiology and pathogenesis of human neural tube defects: insights from mouse models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

29 September 2017

Abnormal folate metabolism in foetuses affected by neural tube defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

27 June 2018

Bacterially synthesized folate in rat large intestine is incorporated into host tissue folyl polyglutamates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

27 June 2018

Folate deficiency alone does not produce neural tube defects in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

27 June 2018

Failure of homocysteine to induce neural tube defects in a mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Impact of methylenetetrahydrofolate reductase deficiency and low dietary folate on the development of neural tube defects in splotch mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Spontaneous neural tube defects in splotch mice supplemented with selected micronutrients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Inhibition of transmethylation disturbs neurulation in chick embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Homocysteine is embryotoxic but does not cause neural tube defects in mouse embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Investigation of the effects of folate deficiency on embryonic development through the establishment of a folate deficient mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Embryonic folate metabolism and mouse neural tube defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Maternal hyperhomocysteinemia: a risk factor for neural-tube defects?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

4 September 2018

Markers of mast cell degranulation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN262

21 January 2018

Folate levels and neural tube defects. Implications for prevention

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN262

21 January 2018

Excess methionine suppresses the methylation cycle and inhibits neural tube closure in mouse embryos

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN262

21 January 2018

Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581426

20 October 2018

Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global DNA methylation measured by liquid chromatography-tandem mass spectrometry: analytical technique, reference values and determinants in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic risk factor for mouse neural tube defects: defining the embryonic basis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible prevention of neural-tube defects by periconceptional vitamin supplementation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural tube defects and sex ratios

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of neural tube defects by and toxicity of L-homocysteine in cultured postimplantation rat embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate levels and neural tube defects. Implications for prevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microbiological assay for serum, plasma, and red cell folate using cryopreserved, microtiter plate method

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fully automated measurement of total homocysteine in plasma and serum on the Abbott IMx analyzer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDN262

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753144%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753144%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753144%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

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