(Q36970245)

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The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells

scientific article published on 06 June 2016

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Europe PubMed Central

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12 March 2020

The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells (English)

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12 March 2020

ubiquitin-proteasome system

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multiple myeloma

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based on heuristic

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corrigendum / erratum

Corrigendum: The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells

1 reference

10.1038/SREP30667

12 July 2019

http://api.crossref.org/works?select=update-to&filter=doi:10.1038/SREP30667

Felicitas Bossler

11

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12 March 2020

Pádraig D'arcy

14

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12 March 2020

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Xin Wang

1

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12 March 2020

Magdalena Mazurkiewicz

2

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12 March 2020

Ellin-Kristina Hillert

3

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12 March 2020

Maria Hägg Olofsson

4

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12 March 2020

Stefan Pierrou

5

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12 March 2020

Per Hillertz

6

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12 March 2020

Joachim Gullbo

7

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12 March 2020

Karthik Selvaraju

8

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12 March 2020

Aneel Paulus

9

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12 March 2020

Sharoon Akhtar

10

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12 March 2020

Asher Chanan Khan

12

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12 March 2020

Stig Linder

13

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12 March 2020

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6 June 2016

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12 March 2020

Scientific Reports

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12 March 2020

6

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12 March 2020

26979

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27264969%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

USP14 activation promotes tumor progression in hepatocellular carcinoma

1 reference

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Ubiquitin-specific protease 14 modulates degradation of cellular prion protein

1 reference

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Synthesis and evaluation of derivatives of the proteasome deubiquitinase inhibitor b-AP15

1 reference

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Molecular basis of resistance to proteasome inhibitors in hematological malignancies

1 reference

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Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction

1 reference

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29 September 2017

Deubiquitinase inhibition as a cancer therapeutic strategy

1 reference

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29 September 2017

Novel targeted agents in the treatment of multiple myeloma

1 reference

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29 September 2017

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry

1 reference

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Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth

1 reference

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Efficient transient transfection of human multiple myeloma cells by electroporation--an appraisal

1 reference

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Small-molecule RA-9 inhibits proteasome-associated DUBs and ovarian cancer in vitro and in vivo via exacerbating unfolded protein responses

1 reference

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29 September 2017

The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death.

1 reference

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29 September 2017

A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer

1 reference

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29 September 2017

A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4893612

29 September 2017

Induction of tumor cell apoptosis by a proteasome deubiquitinase inhibitor is associated with oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4893612

29 September 2017

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4893612

29 September 2017

Deubiquitinase inhibition of 19S regulatory particles by 4-arylidene curcumin analog AC17 causes NF-κB inhibition and p53 reactivation in human lung cancer cells.

1 reference

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29 September 2017

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

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29 September 2017

α,β-Unsaturated carbonyl system of chalcone-based derivatives is responsible for broad inhibition of proteasomal activity and preferential killing of human papilloma virus (HPV) positive cervical cancer cells

1 reference

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29 September 2017

Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis.

1 reference

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29 September 2017

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

1 reference

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29 September 2017

Trimming of Ubiquitin Chains by Proteasome-associated Deubiquitinating Enzymes

1 reference

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29 September 2017

Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation

1 reference

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29 September 2017

Proteasome subunit Rpn13 is a novel ubiquitin receptor

1 reference

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29 September 2017

Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome

1 reference

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A reliable tool to determine cell viability in complex 3-d culture: the acid phosphatase assay

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29 September 2017

Mass spectrometric characterization of the affinity-purified human 26S proteasome complex

1 reference

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29 September 2017

Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

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Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis.

1 reference

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29 September 2017

Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.

1 reference

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29 September 2017

Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

1 reference

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Proteasome inhibitor therapy in multiple myeloma

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29 September 2017

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based on heuristic

inferred from PubMed ID database lookup

Reversible conjugation of ethacrynic acid with glutathione and human glutathione S-transferase P1-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/27264969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin-specific protease 14 (USP14) regulates cellular proliferation and apoptosis in epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27264969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP26979

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27264969%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27264969%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27264969%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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