(Q36973585)

17 August 2017

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title

Therapeutic impact of toll-like receptors on inflammatory bowel diseases: a multiple-edged sword (English)

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inflammatory bowel diseases

17 August 2017

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toll-like receptor

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author name string

Elke Cario

series ordinal

1

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17 August 2017

1 March 2008

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Inflammatory Bowel Diseases

17 August 2017

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17 August 2017

14

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17 August 2017

411-421

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17 August 2017

3

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Unravelling the pathogenesis of inflammatory bowel disease

17 August 2017

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Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

21 January 2018

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Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases.

21 January 2018

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Enteroendocrine cells express functional Toll-like receptors

21 January 2018

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Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells.

21 January 2018

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Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2.

21 January 2018

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Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

21 January 2018

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Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.

21 January 2018

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CD36 is a sensor of diacylglycerides

21 January 2018

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

21 January 2018

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

21 January 2018

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Differences in expression of toll-like receptors and their reactivities in dendritic cells in BALB/c and C57BL/6 mice.

21 January 2018

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Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

21 January 2018

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CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

21 January 2018

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A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2.

21 January 2018

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Toll-like receptor stimulation as a third signal required for activation of human naive B cells.

21 January 2018

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Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement

21 January 2018

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Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

21 January 2018

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IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells

21 January 2018

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Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells

21 January 2018

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Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination.

21 January 2018

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Symbiotic bacteria direct expression of an intestinal bactericidal lectin

21 January 2018

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Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

21 January 2018

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Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine.

21 January 2018

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Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury

21 January 2018

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Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis.

21 January 2018

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Antibodies to interleukin 12 abrogate established experimental colitis in mice

21 January 2018

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Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infection

21 January 2018

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Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

21 January 2018

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NKG2D recognition mediates Toll-like receptor 3 signaling-induced breakdown of epithelial homeostasis in the small intestines of mice

21 January 2018

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Lipopeptide adjuvants in combination treatment

21 January 2018

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Expression and function of Toll-like receptor on T cells

21 January 2018

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TLR2 activation by proteosomes promotes uptake of particulate vaccines at mucosal surfaces

21 January 2018

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Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation.

21 January 2018

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Contrasting activity of cytosin–guanosin dinucleotide oligonucleotides in mice with experimental colitis

21 January 2018

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Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

21 January 2018

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Interleukin-18 secretion and Th1-like cytokine responses in human peripheral blood mononuclear cells under the influence of the toll-like receptor-5 ligand flagellin.

21 January 2018

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Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C

21 January 2018

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Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function

21 January 2018

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Mucin and Toll-like receptors in host defense against intestinal parasites

21 January 2018

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Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells

21 January 2018

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Toll-like receptors, endogenous ligands, and systemic autoimmune disease.

21 January 2018

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TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis.

21 January 2018

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Novel Role of Toll-Like Receptor 3 in Hepatitis C-Associated Glomerulonephritis

21 January 2018

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Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors.

21 January 2018

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Toll-like receptor-7 modulates immune complex glomerulonephritis

21 January 2018

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The role of toll-like receptors in systemic lupus erythematosus.

21 January 2018

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Modulation of atherosclerosis in mice by Toll-like receptor 2

21 January 2018

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Toll-like receptors on tumor cells facilitate evasion of immune surveillance

21 January 2018

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Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

21 January 2018

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Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance

21 January 2018

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TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells

21 January 2018

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Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular Toll-like receptor 4-MD-2 complex

21 January 2018

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IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

21 January 2018

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Gnotobiotic IL-10-/-;NF-kappa B(EGFP) mice reveal the critical role of TLR/NF-kappa B signaling in commensal bacteria-induced colitis.

21 January 2018

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Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a-/- mice

21 January 2018

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Flagellin suppresses epithelial apoptosis and limits disease during enteric infection

21 January 2018

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Induction of human beta-defensin 2 by the probiotic Escherichia coli Nissle 1917 is mediated through flagellin.

21 January 2018

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Bacterial flagellin is a dominant antigen in Crohn disease.

21 January 2018

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Humoral immune response to flagellin requires T cells and activation of innate immunity

21 January 2018

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Toll-like receptor 4 contributes to efficient control of infection with the protozoan parasite Leishmania major

21 January 2018

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Intestinal epithelial TOLLerance versus inTOLLerance of commensals

21 January 2018

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Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut.

21 January 2018

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Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family

21 January 2018

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Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis.

21 January 2018

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Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA.

21 January 2018

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

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The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis.

21 January 2018

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Negative regulation of toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade

21 January 2018

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NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

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Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

21 January 2018

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Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

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CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation

21 January 2018

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Inflammatory bowel disease requires the interplay between innate and adaptive immune signals.

21 January 2018

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In vivo CpG DNA/toll-like receptor 9 interaction induces regulatory properties in CD4+CD62L+ T cells which prevent intestinal inflammation in the SCID transfer model of colitis

21 January 2018

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The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases

21 January 2018

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TLR1- and TLR6-independent Recognition of Bacterial Lipopeptides

21 January 2018

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Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRIL

21 January 2018

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Toll-dependent selection of microbial antigens for presentation by dendritic cells

21 January 2018

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Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

21 January 2018

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Epithelial NEMO links innate immunity to chronic intestinal inflammation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IBD.20294

1 reference

17 August 2017

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PubMed ID

17941072