(Q36977287)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author name string

Kelvin D MacDonald

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Karen R McKenzie

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Mark J Henderson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Charles E Hawkins

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Neeraj Vij

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

publication date

19 September 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Lung Cellular and Molecular Physiology

14 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

295

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

page(s)

L933-40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

Lubiprostone: a chloride channel activator

14 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Cystic fibrosis transmembrane regulator protein mutations: 'class' opportunity for novel drug innovation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Cl- interference with the epithelial Na+ channel ENaC

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

ENaC is inhibited by an increase in the intracellular Cl(-) concentration mediated through activation of Cl(-) channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Loss of hyperpolarization-activated Cl(-) current in salivary acinar cells from Clcn2 knockout mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Distribution of ClC-2 chloride channel in rat and human epithelial tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

ClC-2 Cl- channels in human lung epithelia: activation by arachidonic acid, amidation, and acid-activated omeprazole

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Control of epithelial Na+ conductance by the cystic fibrosis transmembrane conductance regulator

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Chloride channels in the apical membrane of normal and cystic fibrosis airway and intestinal epithelia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

A chloride channel widely expressed in epithelial and non-epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

A synthetic prostone activates apical chloride channels in A6 epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Acidic pH hyperpolarizes nasal potential difference

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Gestational and tissue-specific regulation of C1C-2 chloride channel expression.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Multicenter, 4-week, double-blind, randomized, placebo-controlled trial of lubiprostone, a locally-acting type-2 chloride channel activator, in patients with chronic constipation

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Inhibition of ClC-2 chloride channels by a peptide component or components of scorpion venom.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Mucus clearance and lung function in cystic fibrosis with hypertonic saline

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Basolateral localization of native ClC-2 chloride channels in absorptive intestinal epithelial cells and basolateral sorting encoded by a CBS-2 domain di-leucine motif.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

ClC-5 chloride channel alters expression of the epithelial sodium channel (ENaC).

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Temporal regulation of CFTR expression during ovine lung development: implications for CF gene therapy

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Examining basal chloride transport using the nasal potential difference response in a murine model

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

CIC-2: a developmentally dependent chloride channel expressed in the fetal lung and downregulated after birth.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Hyperabsorption of Na+ and raised Ca(2+)-mediated Cl- secretion in nasal epithelia of CF mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584880

Cell-specific localization of CFTR mRNA shows developmentally regulated expression in human fetal tissues

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18805957

12 December 2020

inferred from PubMed ID database lookup

Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18805957

12 December 2020

inferred from PubMed ID database lookup

Airway liquid: a barrier to drug diffusion?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18805957

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1152/AJPLUNG.90221.2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

release_pdt2lyotrvg2lopo5zpxxhvekm

14 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pdt2lyotrvg2lopo5zpxxhvekm

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805957%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

18805957

1 reference