(Q36977312)

English

CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation.

scientific article published on 29 August 2008

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scholarly article

1 reference

Europe PubMed Central

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13 January 2020

CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation (English)

1 reference

Europe PubMed Central

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13 January 2020

7

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13 January 2020

author name string

Nicholas W Lukacs

1

1 reference

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13 January 2020

Aaron A Berlin

2

1 reference

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13 January 2020

Karin Franz-Bacon

3

1 reference

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13 January 2020

Roman Sásik

4

1 reference

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13 January 2020

L James Sprague

5

1 reference

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13 January 2020

Tai Wei Ly

6

1 reference

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13 January 2020

Stefen A Boehme

8

1 reference

Europe PubMed Central

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13 January 2020

Kevin B Bacon

9

1 reference

Europe PubMed Central

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13 January 2020

language of work or name

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publication date

29 August 2008

1 reference

Europe PubMed Central

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13 January 2020

American Journal of Physiology - Lung Cellular and Molecular Physiology

1 reference

Europe PubMed Central

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13 January 2020

295

1 reference

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13 January 2020

5

1 reference

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13 January 2020

L767-79

1 reference

Europe PubMed Central

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13 January 2020

A key role for CC chemokine receptor 1 in T-cell-mediated respiratory inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

The immunogenetics of asthma and eczema: a new focus on the epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Microarray truths and consequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Controlling false-negative errors in microarray differential expression analysis: a PRIM approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Expression and Molecular Pharmacology of the Mouse CRTH2 Receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Association of a new-type prostaglandin D2 receptor CRTH2 with circulating T helper 2 cells in patients with atopic dermatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Selective expression of a novel surface molecule by human Th2 cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Molecular cloning and characterization of the human prostanoid DP receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

The effects of an oral thromboxane TP receptor antagonist BAY u 3405, on prostaglandin D2- and histamine-induced bronchoconstriction in asthma, and relationship to plasma drug concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

29 September 2017

Release of prostaglandin D2 into human airways during acute antigen challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

27 June 2018

Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

CRTH2 is a prominent effector in contact hypersensitivity-induced neutrophil inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

Expression of prostaglandin D synthase and the prostaglandin D2 receptors DP and CRTH2 in human nasal mucosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

Effects of prostaglandin D2 on helper T cell functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced eosinophilia in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

Trefoil factor-2 is an allergen-induced gene regulated by Th2 cytokines and STAT6 in the lung.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584886

4 September 2018

Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.90351.2008

21 January 2018

Prostaglandin D2 as a mediator of allergic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18757520

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18757520

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mediator release after endobronchial antigen challenge in patients with respiratory allergy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18757520

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BAY u3405, a thromboxane A2 antagonist, reduces bronchial hyperresponsiveness in asthmatics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18757520

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18757520

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPLUNG.90351.2008

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757520%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757520%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757520%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

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