(Q36982611)

English

Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells.

scientific article published on 21 June 2008

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scholarly article

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10 January 2020

Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells (English)

1 reference

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10 January 2020

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5

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10 January 2020

author name string

Rakesh Rathore

1

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10 January 2020

Yun-Min Zheng

2

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10 January 2020

Chun-Feng Niu

3

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10 January 2020

Qing-Hua Liu

4

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10 January 2020

Ye-Shih Ho

6

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10 January 2020

Yong-Xiao Wang

7

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10 January 2020

publication date

21 June 2008

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10 January 2020

Free Radical Biology and Medicine

1 reference

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10 January 2020

45

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10 January 2020

9

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10 January 2020

1223-1231

1 reference

Europe PubMed Central

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10 January 2020

Induction of heme oxygenase-1 in vivo suppresses NADPH oxidase derived oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

Role of mitochondrial reactive oxygen species in hypoxia-dependent increase in intracellular calcium in pulmonary artery myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

Modulation of vascular smooth muscle signaling by reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

Role of reactive oxygen species in vascular remodeling associated with pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

Specific labelling of a constituent polypeptide of bovine heart mitochondrial reduced nicotinamide-adenine dinucleotide-ubiquinone reductase by the inhibitor diphenyleneiodonium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

Hydrogen peroxide induced pulmonary vasoconstriction in isolated rat lungs is attenuated by U60,257, a leucotriene synthesis blocker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

29 September 2017

Mitochondrial ROS-PKCepsilon signaling axis is uniquely involved in hypoxic increase in [Ca2+]i in pulmonary artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

27 June 2018

Cytosolic NADPH may regulate differences in basal Nox oxidase-derived superoxide generation in bovine coronary and pulmonary arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

27 June 2018

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

27 June 2018

A redox-based O2 sensor in rat pulmonary vasculature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

27 June 2018

Pulmonary arterial hypoxic contraction: signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

27 June 2018

The protective role of cellular glutathione peroxidase against trauma-induced mitochondrial dysfunction in the mouse brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Hydrogen peroxide-induced Ca2+ mobilization in pulmonary arterial smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Impact of mitochondria and NADPH oxidases on acute and sustained hypoxic pulmonary vasoconstriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Hypoxic pulmonary hypertension: role of superoxide and NADPH oxidase (gp91phox).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Hypoxic pulmonary vasoconstriction and pulmonary artery tissue cytokine expression are mediated by protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Contribution of oxygen radicals to altered NO-dependent pulmonary vasodilation in acute and chronic hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Hypoxic constriction and reactive oxygen species in porcine distal pulmonary arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Protein kinase C-epsilon-null mice have decreased hypoxic pulmonary vasoconstriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Metabolic inhibition with cyanide induces calcium release in pulmonary artery myocytes and Xenopus oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Diversity in mitochondrial function explains differences in vascular oxygen sensing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Functional evaluation of nonphagocytic NAD(P)H oxidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Potassium channels modulate canine pulmonary vasoreactivity to protein kinase C activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Pulmonary artery NADPH-oxidase is activated in hypoxic pulmonary vasoconstriction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Properties of a superoxide anion-generating microsomal NADH oxidoreductase, a potential pulmonary artery PO2 sensor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Reactive oxygen species alter contractile properties of pulmonary arterial smooth muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586914

4 September 2018

Role of ion fluxes in hydrogen peroxide pulmonary vasoconstriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radical production in hypoxic pulmonary artery smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic vasoconstriction in intact lungs: a role for NADPH oxidase-derived H(2)O(2)?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constriction and Dilatation of Pulmonary Arterial Ring by Hydrogen Peroxide - Importance of Prostanoids -

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxic oxygen metabolites induce vasoconstriction and bronchoconstriction in isolated, plasma-perfused rat lungs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic pulmonary vasoconstriction--triggered by an increase in reactive oxygen species?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of NADPH oxidase inhibitors on hypoxic vasoconstriction in buffer-perfused rabbit lungs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C influences rat pulmonary vascular reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a role of protein kinase C in hypoxic pulmonary vasoconstriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulmonary artery smooth muscle cell [Ca2+]i and contraction: responses to diphenyleneiodonium and hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of hydrogen peroxide on hypoxia, prostaglandin F2 alpha and potassium chloride induced contractions in isolated rat pulmonary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of hypoxia and norepinephrine on cytoplasmic free Ca2+ in pulmonary and cerebral arterial myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glutathione redox cycle as a defense system against hydrogen-peroxide-induced prostanoid formation and vasoconstriction in rabbit lungs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of hypoxic pulmonary vasoconstriction by diphenyleneiodonium

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of tyrosine kinases in H2O2-induced contraction in pulmonary artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and mechanisms of H2O2-induced contractions of pulmonary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role of NADH oxidoreductase-derived reactive O2 species in calf pulmonary arterial PO2-elicited responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18638544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.FREERADBIOMED.2008.06.012

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18638544%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18638544%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18638544%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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