(Q36986476)

17 August 2017

Spdef null mice lack conjunctival goblet cells and provide a model of dry eye. (English)

1 reference

17 August 2017

Christina K Marko

1

1 reference

17 August 2017

Balaraj B Menon

2

1 reference

17 August 2017

Gang Chen

3

1 reference

17 August 2017

Jeffrey A Whitsett

4

1 reference

17 August 2017

Hans Clevers

5

1 reference

17 August 2017

Ilene K Gipson

6

1 reference

17 August 2017

language of work or name

English

0 references

publication date

10 May 2013

1 reference

The American Journal of Pathology

17 August 2017

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17 August 2017

183

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17 August 2017

1

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17 August 2017

35-48

1 reference

describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3702735/fullTextXML

inferred from PubMed Central ID database lookup

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Efficacy of topical blockade of interleukin-1 in experimental dry eye disease

29 September 2017

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Ocular surface immunity: homeostatic mechanisms and their disruption in dry eye disease

29 September 2017

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A metalloproteinase secreted by Streptococcus pneumoniae removes membrane mucin MUC16 from the epithelial glycocalyx barrier

29 September 2017

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Low humidity environmental challenge causes barrier disruption and cornification of the mouse corneal epithelium via a c-jun N-terminal kinase 2 (JNK2) pathway

29 September 2017

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Comparison of mucin levels at the ocular surface of postmenopausal women with and without a history of dry eye

29 September 2017

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Entrapment of conjunctival goblet cells by desiccation-induced cornification

29 September 2017

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Mouse conjunctival forniceal gene expression during postnatal development and its regulation by Kruppel-like factor 4.

29 September 2017

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Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin

29 September 2017

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Membrane-tethered mucins have multiple functions on the ocular surface.

29 September 2017

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SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells.

29 September 2017

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SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

29 September 2017

1 reference

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The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium

29 September 2017

1 reference

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Corneal epithelial proliferation and thickness in a mouse model of dry eye.

29 September 2017

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

29 September 2017

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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

29 September 2017

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Trefoil factor TFF1-induced protection of conjunctival cells from apoptosis at premitochondrial and postmitochondrial levels

29 September 2017

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The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development

29 September 2017

1 reference

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Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

29 September 2017

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Functions of MUC16 in corneal epithelial cells

29 September 2017

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SPDEF regulates goblet cell hyperplasia in the airway epithelium

29 September 2017

1 reference

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Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells

29 September 2017

1 reference

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IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production

29 September 2017

1 reference

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A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth

29 September 2017

1 reference

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Expression and regulation of cornified envelope proteins in human corneal epithelium

29 September 2017

1 reference

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Wnt signaling in the intestinal epithelium: from endoderm to cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Wnt signalling induces maturation of Paneth cells in intestinal crypts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Animal models of dry eye: a critical assessment of opportunities and limitations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Neurturin-Deficient Mice Develop Dry Eye and Keratoconjunctivitis Sicca

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Secreted antagonists of the Wnt signalling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Mucin gene expression in immortalized human corneal-limbal and conjunctival epithelial cell lines.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

The cell-layer- and cell-type-specific distribution of GalNAc-transferases in the ocular surface epithelia is altered during keratinization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Secreted Frizzled-related proteins: searching for relationships and patterns

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

The ocular surface and tear film and their dysfunction in dry eye disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Homeostatic control of conjunctival mucosal goblet cells by NKT-derived IL-13.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Depletion of passenger leukocytes from corneal grafts: an effective means of promoting transplant survival?

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

A mouse model of keratoconjunctivitis sicca.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Clonal analysis of the in vivo differentiation potential of keratinocytes.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

In vitro growth and differentiation of rabbit bulbar, fornix, and palpebral conjunctival epithelia. Implications on conjunctival epithelial transdifferentiation and stem cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Resolvin E1 (RX-10001) reduces corneal epithelial barrier disruption and protects against goblet cell loss in a murine model of dry eye.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Dkk2 plays an essential role in the corneal fate of the ocular surface epithelium.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

The controlled-environment chamber: a new mouse model of dry eye.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Interleukin-13 induces goblet cell differentiation in primary cell culture from Guinea pig tracheal epithelium

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Quantification of MUC5AC protein in human tears

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Variations in human corneal endothelial cell morphology and permeability to fluorescein with age

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Hyperosmolarity-Induced Cornification of Human Corneal Epithelial Cells Is Regulated by JNK MAPK

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702735

Exposure to a dry environment induces strain-specific responses in mice

4 December 2018

1 reference

12 December 2020

Changes in corneal autofluorescence and corneal epithelial barrier function with aging

1 reference

12 December 2020

Label-retaining cells are preferentially located in fornical epithelium: implications on conjunctival epithelial homeostasis

1 reference

12 December 2020

Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis sicca

1 reference

12 December 2020

Elevated expression of transglutaminase 1 and keratinization-related proteins in conjunctiva in severe ocular surface disease

1 reference

12 December 2020

Alteration in goblet cell numbers and mucin gene expression in a mouse model of allergic conjunctivitis.

1 reference

12 December 2020

Decreased levels of the goblet cell mucin MUC5AC in tears of patients with Sjögren syndrome

1 reference

12 December 2020

Dry Eye–Induced Conjunctival Epithelial Squamous Metaplasia Is Modulated by Interferon-γ

1 reference

12 December 2020

Research in dry eye: report of the Research Subcommittee of the International Dry Eye WorkShop (2007)

1 reference

12 December 2020

10.1016/J.AJPATH.2013.03.017

Identifiers

DOI

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23665202

1 reference