(Q37004584)

17 August 2017

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title

Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation (English)

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17 August 2017

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Marion Jurk

1

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17 August 2017

Jörg Vollmer

series ordinal

2

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17 August 2017

publication date

1 January 2007

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17 August 2017

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17 August 2017

volume

21

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17 August 2017

issue

6

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17 August 2017

page(s)

387-401

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Subcellular localization of Toll-like receptor 3 in human dendritic cells

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Mechanism and function of a newly identified CpG DNA motif in human primary B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

CXCL16 influences the nature and specificity of CpG-induced immune activation

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Oligodeoxynucleotides differentially modulate activation of TLR7 and TLR8 by imidazoquinolines

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Suppressive oligodeoxynucleotides inhibit Th1 differentiation by blocking IFN-gamma- and IL-12-mediated signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Suppressive oligodeoxynucleotides protect mice from lethal endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Cutting edge: species-specific TLR9-mediated recognition of CpG and non-CpG phosphorothioate-modified oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Oligodeoxynucleotides without CpG motifs work as adjuvant for the induction of Th2 differentiation in a sequence-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Induction of potent antitumor immunity by in situ targeting of intratumoral DCs.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Intratumor CpG-Oligodeoxynucleotide Injection Induces Protective Antitumor T Cell Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

CpG oligodeoxynucleotides inhibit tumor growth and reverse the immunosuppression caused by the therapy with 5-fluorouracil in murine hepatoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

NK- and CD8(+) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Absence of the CD1 molecule up-regulates antitumor activity induced by CpG oligodeoxynucleotides in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Inhibition of experimental asthma by indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Immunostimulatory DNA sequences influence the course of adjuvant arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Toll-like receptor 9-induced type I IFN protects mice from experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques to augment the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Baculovirus induces an innate immune response and confers protection from lethal influenza virus infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

CpG oligodeoxynucleotides protect newborn mice from a lethal challenge with the neurotropic Tacaribe arenavirus.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

The potential of immunostimulatory CpG DNA for inducing immunity against genital herpes: opportunities and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Anti-HBV effects of CpG oligodeoxynucleotide-activated peripheral blood mononuclear cells from patients with chronic hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Endogenous IFN-alpha production by plasmacytoid dendritic cells exerts an antiviral effect on thymic HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Toll-Like Receptor 2 (TLR2) and TLR9 Signaling Results in HIV-Long Terminal RepeatTrans-Activation and HIV Replication in HIV-1 Transgenic Mouse Spleen Cells: Implications of Simultaneous Activation of TLRs on HIV Replication

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00063030-200721060-00006

10.2165/00063030-200721060-00006

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

17 August 2017

1022633898

0 references

1 reference