(Q37016158)

17 August 2017

Synthesis, retention, and biological activity of methotrexate polyglutamates in cultured human breast cancer cells (English)

1 reference

https://api.crossref.org/works/10.1172/JCI110624

17 August 2017

Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer Cells (English)

1 reference

22 August 2023

0 references

1 reference

1 reference

J. Jolivet

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6178756

22 August 2023

R. L. Schilsky

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6178756

22 August 2023

B. D. Bailey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6178756

22 August 2023

J. C. Drake

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6178756

22 August 2023

B. A. Chabner

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6178756

22 August 2023

language of work or name

English

0 references

publication date

1 August 1982

1 reference

full work available at URL

17 August 2017

https://europepmc.org/articles/PMC371243

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6178756

https://europepmc.org/articles/PMC371243?pdf=render

22 August 2023

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6178756

http://www.jci.org/articles/view/110624/files/pdf

22 August 2023

1 reference

https://api.crossref.org/works/10.1172/JCI110624

Journal of Clinical Investigation

22 August 2023

published in

1 reference

17 August 2017

70

1 reference

17 August 2017

2

1 reference

17 August 2017

351-360

1 reference

describes a project that uses

17 August 2017

ZR-75-B

0 references

cites work

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Transport, binding, and polyglutamation of methotrexate in freshly isolated rat hepatocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Methotrexate polyglutamate synthesis by cultured human breast cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Breast tumor cell lines from pleural effusions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

A human cell line from a pleural effusion derived from a breast carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Tissue-specific synthesis of methotrexate polyglutamates in the rat

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Competitive protein binding assay for methotrexate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Natural resistance to methotrexate in human acute nonlymphocytic leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

The application of rapid kinetic techniques to the transport of thymidine and 3-O-methylglucose into mammalian cells in suspension culture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Effects of methotrexate esters and other lipophilic antifolates on methotrexate-resistant human leukemic lymphoblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Synthesis and biological evaluation of poly-gamma-glutamyl derivatives of methotrexate.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Polygammaglutamyl metabolites of methotrexate.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Establishment and characterization of three new continuous cell lines derived from human breast carcinomas

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

Accumulation of methotrexate diglutamate in human liver during methotrexate therapy

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371243

The mechanism of action of methotrexate. III. Requirement of free intracellular methotrexate for maximal suppression of (14C)formate incorporation into nucleic acids and protein

27 June 2018

1 reference

12 December 2020

Synthesis of methotrexate polyglutamates in cultured human cells

1 reference

12 December 2020

Prolonged inhibition of DNA synthesis associated with the accumulation of methotrexate polyglutamates by cultured human cells

1 reference

12 December 2020

Polyglutamate derivatives of folic acid coenzymes and methotrexate

1 reference

12 December 2020

Evidence for the cytotoxic activity of polyglutamate derivatives of methotrexate

1 reference

12 December 2020

Extracellular recovery of methotrexate-polyglutamates following efflux from L1210 leukemia cells

1 reference

12 December 2020

Carrier-mediated Transport of the Folic Acid Analogue, Methotrexate, in the L1210 Leukemia Cell

1 reference

12 December 2020

Synthesis of methotrexate polyglutamates by bone marrow cells from patients with leukemia and lymphoma

1 reference

12 December 2020

Efflux of methotrexate and its polyglutamate derivatives from hepatic cells in vitro

1 reference

12 December 2020

High-pressure liquid chromatography analysis of methotrexate polyglutamates in cultured human breast cancer cells

1 reference

12 December 2020

Characteristics of membrane transport of methotrexate by cultured human breast cancer cells

1 reference

12 December 2020

Differential synthesis of methotrexate polyglutamates in normal proliferative and neoplastic mouse tissues in vivo

1 reference

12 December 2020

Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro

1 reference

12 December 2020

Enzymatic reduction of dihydrofolic acid

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI110624

1 reference

17 August 2017

1 reference

17 August 2017

1 reference