(Q37027406)

17 August 2017

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title

Myeloma cells and bone marrow osteoblast interactions: role in the development of osteolytic lesions in multiple myeloma (English)

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17 August 2017

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Nicola Giuliani

1

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17 August 2017

Vittorio Rizzoli

series ordinal

2

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17 August 2017

publication date

1 December 2007

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17 August 2017

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17 August 2017

volume

48

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17 August 2017

issue

12

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17 August 2017

page(s)

2323-2329

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https://api.crossref.org/works/10.1080%2F10428190701648281

17 August 2017

1 reference

New insight in the mechanism of osteoclast activation and formation in multiple myeloma: focus on the receptor activator of NF-kappaB ligand (RANKL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Marked osteoblastopenia and reduced bone formation in a model of multiple myeloma bone disease in severe combined immunodeficiency mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Myeloma affects both the growth and function of human osteoblast-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Minireview: transcriptional regulation in development of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Anti-alpha4 integrin antibody suppresses the development of multiple myeloma and associated osteoclastic osteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Production of fibronectin and adherence to fibronectin by human myeloma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Expression of CD56/neural cell adhesion molecule correlates with the presence of lytic bone lesions in multiple myeloma and distinguishes myeloma from monoclonal gammopathy of undetermined significance and lymphomas with plasmacytoid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

IL-3 is a potential inhibitor of osteoblast differentiation in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Wnt signaling in osteoblasts and bone diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Regulation of bone mass by Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

High bone density due to a mutation in LDL-receptor-related protein 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Wnt signaling inhibits osteogenic differentiation of human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Canonical and non-canonical Wnts differentially affect the development potential of primary isolate of human bone marrow mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Dickkopf-1 induced apoptosis in human placental choriocarcinoma is independent of canonical Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Bone lesions in molecular subtypes of multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Proteasome inhibition in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Response to bortezomib and activation of osteoblasts in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

High serum bone-specific alkaline phosphatase level after bortezomib-combined therapy in refractory multiple myeloma: possible role of bortezomib on osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

Bortezomib reduces serum dickkopf-1 and receptor activator of nuclear factor-?B ligand concentrations and normalises indices of bone remodelling in patients with relapsed multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701648281

10.1080/10428190701648281

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference