(Q37029906)

17 August 2017

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title

Cathepsin K inhibitors: a novel target for osteoporosis therapy (English)

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17 August 2017

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Stoch SA

1

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17 August 2017

Wagner JA

series ordinal

2

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17 August 2017

language of work or name

English

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publication date

12 December 2007

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Clinical Pharmacology & Therapeutics

17 August 2017

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17 August 2017

83

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17 August 2017

1

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17 August 2017

172-176

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https://scigraph.springernature.com/pub.10.1038/sj.clpt.6100450

17 August 2017

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cites work

Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

On the mechanisms of bone resorption. The action of parathyroid hormone on the excretion and synthesis of lysosomal enzymes and on the extracellular release of acid by bone cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

Identification of a potent and selective non-basic cathepsin K inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

Development and characterization of a human in vitro resorption assay: demonstration of utility using novel antiresorptive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

Azepanone-based inhibitors of human and rat cathepsin K

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

A potent small molecule, nonpeptide inhibitor of cathepsin K (SB 331750) prevents bone matrix resorption in the ovariectomized rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

Fracture incidence and characterization in patients on osteoporosis treatment: the ICARO study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

Determination of bone markers in pycnodysostosis: effects of cathepsin K deficiency on bone matrix degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

Decreased bone turnover and deterioration of bone structure in two cases of pycnodysostosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

The role of cathepsin K in normal bone resorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

7 January 2021

Dimerization of midkine by tissue transglutaminase and its functional implication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

7 January 2021

Study of immunoelectron microscopic localization of cathepsin K in osteoclasts and other bone cells in the mouse femur

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

7 January 2021

Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

7 January 2021

Cloning and expression of rhesus monkey cathepsin K

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

7 January 2021

Zoledronate prevents the development of absolute osteopenia following ovariectomy in adult rhesus monkeys

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

7 January 2021

An animal model for pycnodysostosis: the role of cathepsin K in bone remodelling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

7 January 2021

Accelerated turnover of metaphyseal trabecular bone in mice overexpressing cathepsin K

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

7 January 2021

Synthesis of peptide aldehyde derivatives as selective inhibitors of human cathepsin L and their inhibitory effect on bone resorption

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100450

7 January 2021

Identifiers

DOI

10.1038/SJ.CLPT.6100450

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Dimensions Publication ID

17 August 2017

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