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English
Uncoupling protein 2 regulates metabolic reprogramming and fate of antigen-stimulated CD8+ T cells.
scientific article published on 06 June 2016
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
review article
1 reference
stated in
Europe PubMed Central
title
Uncoupling protein 2 regulates metabolic reprogramming and fate of antigen-stimulated CD8+ T cells
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
author
Rupesh K Srivastava
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
author name string
Leena Chaudhuri
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Ferdynand Kos
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Protul A Shrikant
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
publication date
6 June 2016
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
published in
Cancer Immunology, Immunotherapy
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
volume
65
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
page(s)
869-874
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
exact match
https://scigraph.springernature.com/pub.10.1007/s00262-016-1851-4
0 references
cites work
T cell metabolism drives immunity
1 reference
stated in
PubMed Central
reference URL
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29 September 2017
Immune checkpoint blockade: a common denominator approach to cancer therapy
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PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
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PubMed Central
reference URL
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29 September 2017
Mitochondria in the regulation of innate and adaptive immunity
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UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation.
1 reference
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PubMed Central
reference URL
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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.
1 reference
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Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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29 September 2017
Metabolic regulation of T lymphocytes
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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29 September 2017
Metabolic checkpoints in activated T cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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29 September 2017
Quantification of uncoupling protein 2 reveals its main expression in immune cells and selective up-regulation during T-cell proliferation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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The blockade of immune checkpoints in cancer immunotherapy
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PubMed Central
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29 September 2017
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development
1 reference
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PubMed Central
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29 September 2017
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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29 September 2017
Aerobic glycolysis: meeting the metabolic requirements of cell proliferation
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PubMed Central
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29 September 2017
Metabolic flux and the regulation of mammalian cell growth
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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29 September 2017
Uncoupling protein UCP2: when mitochondrial activity meets immunity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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29 September 2017
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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29 September 2017
Understanding the Warburg effect: the metabolic requirements of cell proliferation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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29 September 2017
UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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29 September 2017
Novel role for mitochondria: protein kinase Ctheta-dependent oxidative signaling organelles in activation-induced T-cell death
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
retrieved
29 September 2017
UCP2, UCP3, avUCP, what do they do when proton transport is not stimulated? Possible relevance to pyruvate and glutamine metabolism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
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Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production
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reference URL
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29 September 2017
Lineage relationship and protective immunity of memory CD8 T cell subsets
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PubMed Central
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29 September 2017
Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages
1 reference
stated in
PubMed Central
reference URL
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Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression
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29 September 2017
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
1 reference
stated in
PubMed Central
reference URL
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29 September 2017
Mitochondrial ROS fire up T cell activation.
1 reference
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PubMed Central
reference URL
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4 September 2018
UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
retrieved
4 September 2018
Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4919150
retrieved
4 September 2018
The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27271549
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S00262-016-1851-4
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PMCID
4919150
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PubMed ID
27271549
1 reference
stated in
Europe PubMed Central
PMCID
4919150
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27271549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
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