(Q37036711)

English

Pyrrolidine dithiocarbamate inhibits herpes simplex virus 1 and 2 replication, and its activity may be mediated through dysregulation of the ubiquitin-proteasome system

scientific article published on 05 June 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Pyrrolidine dithiocarbamate inhibits herpes simplex virus 1 and 2 replication, and its activity may be mediated through dysregulation of the ubiquitin-proteasome system (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ubiquitin-proteasome system

0 references

author name string

Min Qiu

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Yu Chen

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Lin Cheng

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Ying Chu

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Hong-Yong Song

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Zhi-Wei Wu

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

5 June 2013

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Journal of Virology

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

87

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

15

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

8675-8686

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

The ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cells

1 reference

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Hepatitis E virus replication requires an active ubiquitin-proteasome system

1 reference

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9 September 2017

HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6

1 reference

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Protein cross-linking as a novel mechanism of action of a ubiquitin-activating enzyme inhibitor with anti-tumor activity.

1 reference

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9 September 2017

A pre-immediate-early role for tegument ICP0 in the proteasome-dependent entry of herpes simplex virus

1 reference

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9 September 2017

The herpes simplex virus immediate-early ubiquitin ligase ICP0 induces degradation of the ICP0 repressor protein E2FBP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion step

1 reference

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9 September 2017

Herpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2.

1 reference

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9 September 2017

Role of Infection in the Pathogenesis of Alzheimerʼs Disease

1 reference

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9 September 2017

Promyelocytic leukemia-nuclear body proteins: herpesvirus enemies, accomplices, or both?

1 reference

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9 September 2017

Inhibition of the ubiquitin-proteasome system prevents vaccinia virus DNA replication and expression of intermediate and late genes

1 reference

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9 September 2017

Ubiquitination is required for effective replication of coxsackievirus B3.

1 reference

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9 September 2017

Herpes simplex virus type 1 in Alzheimer's disease: the enemy within

1 reference

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9 September 2017

Different effect of proteasome inhibition on vesicular stomatitis virus and poliovirus replication

1 reference

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9 September 2017

Cellular proteasome activity facilitates herpes simplex virus entry at a postpenetration step

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

PML and PML nuclear bodies: implications in antiviral defence

1 reference

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9 September 2017

Centromeric protein CENP-B proteasomal degradation induced by the viral protein ICP0.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

1 reference

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9 September 2017

PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

The ubiquitin-proteasome system in HIV replication: potential targets for antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Efficient replication by herpes simplex virus type 1 involves activation of the IkappaB kinase-IkappaB-p65 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Back to the future with ubiquitin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

PML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Evidence that reactive oxygen species do not mediate NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Role and fate of PML nuclear bodies in response to interferon and viral infections

1 reference

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9 September 2017

Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Requirements for the nuclear-cytoplasmic translocation of infected-cell protein 0 of herpes simplex virus 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Proteasome inhibitor induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Degradation of nucleosome-associated centromeric histone H3-like protein CENP-A induced by herpes simplex virus type 1 protein ICP0

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Death signaling pathway induced by pyrrolidine dithiocarbamate-Cu(2+) complex in the cultured rat cortical astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

ICP0, a regulator of herpes simplex virus during lytic and latent infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Novel biphasic effect of pyrrolidine dithiocarbamate on neuronal cell viability is mediated by the differential regulation of intracellular zinc and copper ion levels, NF-kappaB, and MAP kinases

1 reference

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The role of the E6-p53 interaction in the molecular pathogenesis of HPV.

1 reference

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9 September 2017

The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms

1 reference

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9 September 2017

CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway

1 reference

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Oxidative stress in human immunodeficiency virus infection

1 reference

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Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasm

1 reference

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9 September 2017

Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation

1 reference

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9 September 2017

Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

9 September 2017

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

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The ubiquitin-proteasome pathway is important for dengue virus infection in primary human endothelial cells

1 reference

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29 September 2017

The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle

1 reference

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PDTC inhibits picornavirus polyprotein processing and RNA replication by transporting zinc ions into cells

1 reference

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29 September 2017

Antiviral activity of proteasome inhibitors in herpes simplex virus-1 infection: role of nuclear factor-kappaB.

1 reference

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29 September 2017

Inhibition of polyprotein processing and RNA replication of human rhinovirus by pyrrolidine dithiocarbamate involves metal ions.

1 reference

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29 September 2017

Activation of NF-kappaB is involved in 6-hydroxydopamine-but not MPP+ -induced dopaminergic neuronal cell death: its potential role as a survival determinant

1 reference

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29 September 2017

Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0.

1 reference

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29 September 2017

Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway

1 reference

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29 September 2017

Ubiquitin-dependent proteolysis of cyclin D1 is associated with coxsackievirus-induced cell growth arrest

1 reference

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29 September 2017

Antiviral effects of pyrrolidine dithiocarbamate on human rhinoviruses

1 reference

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29 September 2017

Herpes simplex virus type 1 immediate-early protein ICP0 and is isolated RING finger domain act as ubiquitin E3 ligases in vitro

1 reference

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29 September 2017

Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase.

1 reference

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29 September 2017

Activation of cJUN N-terminal kinase by herpes simplex virus type 1 enhances viral replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

29 September 2017

Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

29 September 2017

Herpes simplex virus type 1 infection stimulates p38/c-Jun N-terminal mitogen-activated protein kinase pathways and activates transcription factor AP-1.

1 reference

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29 September 2017

The role of oxidative stress in HIV disease

1 reference

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29 September 2017

A detailed analysis of an HSV-1 early promoter: sequences involved in trans-activation by viral immediate-early gene products are not early-gene specific

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

29 September 2017

A detailed mutational analysis of Vmw110, a trans-acting transcriptional activator encoded by herpes simplex virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

29 September 2017

Orthopoxviruses require a functional ubiquitin-proteasome system for productive replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

27 June 2018

Pyrrolidine dithiocarbamate reduces coxsackievirus B3 replication through inhibition of the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

27 June 2018

Proteasome inhibition reduces coxsackievirus B3 replication in murine cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

27 June 2018

Zinc is required in pyrrolidine dithiocarbamate inhibition of NF-kappaB activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

27 June 2018

A viral activator of gene expression functions via the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

27 June 2018

Pyrrolidine dithiocarbamate inhibits NF-kappa B mobilization and TNF production in human monocytes

1 reference

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27 June 2018

Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activity

1 reference

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27 June 2018

The role of herpes simplex virus type 2 and other genital infections in the acquisition of HIV-1 among high-risk women in northern Tanzania

1 reference

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4 September 2018

Association of herpes simplex virus type 2 infection and syphilis with human immunodeficiency virus infection among men who have sex with men in Peru

1 reference

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4 September 2018

Inhibition of the stress-activated kinase, p38, does not affect the virus transcriptional program of herpes simplex virus type 1.

1 reference

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4 September 2018

Pyrrolidine dithiocarbamate and zinc inhibit proteasome-dependent proteolysis

1 reference

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4 September 2018

Viruses and the 26S proteasome: hacking into destruction

1 reference

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4 September 2018

Changes in plasma human immunodeficiency virus type 1 RNA associated with herpes simplex virus reactivation and suppression

1 reference

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4 September 2018

Effect of antioxidants on apoptosis induced by influenza virus infection: inhibition of viral gene replication and transcription with pyrrolidine dithiocarbamate

1 reference

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4 September 2018

Redox-regulated mechanisms of IL-4-induced MCP-1 expression in human vascular endothelial cells

1 reference

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4 September 2018

Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

4 September 2018

Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

4 September 2018

Herpes simplex type 1 induction of persistent NF-kappa B nuclear translocation increases the efficiency of virus replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719803

4 September 2018

Pyrrolidine dithiocarbamate-induced apoptosis depends on cell type, density, and the presence of Cu(2+) and Zn(2+)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23740985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00869-13

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

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