(Q37038041)

English

PCPH/ENTPD5 expression confers to prostate cancer cells resistance against cisplatin-induced apoptosis through protein kinase Calpha-mediated Bcl-2 stabilization

scientific article published on January 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PCPH/ENTPD5 expression confers to prostate cancer cells resistance against cisplatin-induced apoptosis through protein kinase Calpha-mediated Bcl-2 stabilization (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

apoptotic process

0 references

prostate cancer

1 reference

based on heuristic

inferred from title

author name string

Joaquín Villar

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Humair S Quadri

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Insun Song

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

York Tomita

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Oscar M Tirado

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Vicente Notario

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

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publication date

1 January 2009

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Europe PubMed Central

PMC publication ID

17 August 2017

Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

69

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

102-110

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Current status and future prospects for satraplatin, an oral platinum analogue

1 reference

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29 September 2017

Regulation of Bcl-2 family proteins by posttranslational modifications.

1 reference

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29 September 2017

PCPH/ENTPD5 expression enhances the invasiveness of human prostate cancer cells by a protein kinase C delta-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Peroxide is a key mediator of Bcl-2 down-regulation and apoptosis induction by cisplatin in human lung cancer cells

1 reference

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29 September 2017

Protein kinase Cepsilon makes the life and death decision

1 reference

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29 September 2017

Mechanism of inhibition of sequestration of protein kinase C alpha/betaII by ceramide. Roles of ceramide-activated protein phosphatases and phosphorylation/dephosphorylation of protein kinase C alpha/betaII on threonine 638/641.

1 reference

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29 September 2017

Protein kinase C and other diacylglycerol effectors in cancer

1 reference

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29 September 2017

PKCdelta signaling: mechanisms of DNA damage response and apoptosis

1 reference

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29 September 2017

The Bcl-2 apoptotic switch in cancer development and therapy

1 reference

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29 September 2017

Cancer statistics, 2007

1 reference

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29 September 2017

Is there a role for platinum chemotherapy in the treatment of patients with hormone-refractory prostate cancer?

1 reference

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29 September 2017

c-Myc-dependent etoposide-induced apoptosis involves activation of Bax and caspases, and PKCdelta signaling

1 reference

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29 September 2017

A spatiotemporally coordinated cascade of protein kinase C activation controls isoform-selective translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

PCPH expression is an early event in the development of testicular germ cell tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Posttranslational modifications of Bcl2 family members--a potential therapeutic target for human malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Molecular mechanisms of protein kinase C-induced apoptosis in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Apoptosis evasion: the role of survival pathways in prostate cancer progression and therapeutic resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Upregulation of Bcl-2 is associated with cisplatin-resistance via inhibition of Bax translocation in human bladder cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Roles of tyrosine phosphorylation and cleavage of protein kinase Cdelta in its protective effect against tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Phorbol ester-induced apoptosis of C4-2 cells requires both a unique and a redundant protein kinase C signaling pathway.

1 reference

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29 September 2017

Protein kinase C and prostate carcinogenesis: targeting the cell cycle and apoptotic mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Pathological and molecular aspects of prostate cancer

1 reference

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29 September 2017

Regulation of cell apoptosis by protein kinase c delta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Gradual deregulation and loss of PCPH expression in the progression of human laryngeal neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Identity between the PCPH proto-oncogene and the CD39L4 (ENTPD5) ectonucleoside triphosphate diphosphohydrolase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

Phosphorylation of Bcl2 and regulation of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

29 September 2017

The role of protein kinase C isoforms in cell proliferation and apoptosis.

1 reference

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29 September 2017

Protein kinase C isozymes and the regulation of diverse cell responses

1 reference

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29 September 2017

Both normal and transforming PCPH proteins have guanosine diphosphatase activity but only the oncoprotein cooperates with Ras in activating extracellular signal-regulated kinase ERK1

1 reference

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29 September 2017

Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.

1 reference

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29 September 2017

The product of the cph oncogene is a truncated, nucleotide-binding protein that enhances cellular survival to stress

1 reference

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29 September 2017

Protein kinase C is regulated in vivo by three functionally distinct phosphorylations

1 reference

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29 September 2017

cph, a novel oncogene which cooperates with H-ras in the transformation of NIH3T3 fibroblasts

1 reference

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29 September 2017

Deregulated expression of the PCPH proto-oncogene in human breast cancers.

1 reference

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27 June 2018

The PCPH oncoprotein antagonizes the proapoptotic role of the mammalian target of rapamycin in the response of normal fibroblasts to ionizing radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

27 June 2018

The involvement of protein kinase C isoenzymes alpha, epsilon and zeta in the sensitivity to antitumor treatment and apoptosis induction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

27 June 2018

Protein kinase C isoenzyme patterns characteristically modulated in early prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

27 June 2018

PKC inhibitor Go6976 induces mitosis and enhances doxorubicin-paclitaxel cytotoxicity in urinary bladder carcinoma cells.

1 reference

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4 September 2018

Enhancement of cisplatin sensitivity of cisplatin-resistant human cervical carcinoma cells by bryostatin 1.

1 reference

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4 September 2018

Synthesis of anilino-monoindolylmaleimides as potent and selective PKCbeta inhibitors.

1 reference

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4 September 2018

PKC alpha mediates chemoresistance in acute lymphoblastic leukemia through effects on Bcl2 phosphorylation

1 reference

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4 September 2018

Ribozyme-mediated inhibition of PKCalpha sensitizes androgen-independent human prostate cancer cells to cisplatin-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

4 September 2018

Signal-induced site specific phosphorylation targets Bcl2 to the proteasome pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

4 September 2018

Partial depletion of intracellular ATP mediates the stress-survival function of the PCPH oncoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

4 September 2018

Deregulated expression of the PCPH proto-oncogene in rat mammary tumors induced with 7,12-dimethylbenz[a]anthracene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614304

4 September 2018

Involvement of protein kinase C-delta in DNA damage-induced apoptosis

1 reference

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4 September 2018

Expression of the protein product of the PCPH proto-oncogene in human tumor cell lines.

1 reference

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4 September 2018

Tissue-specific expression, evolutionary conservation and localization of the cph proto-oncogene on Syrian hamster chromosome X.

1 reference

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4 September 2018

Identifiers

10.1158/0008-5472.CAN-08-2922

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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