(Q37049524)

17 August 2017

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title

p53 tumor suppressor gene: a critical molecular target for UV induction and prevention of skin cancer (English)

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17 August 2017

Cara L Benjamin

1

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17 August 2017

Stephen E Ullrich

series ordinal

2

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17 August 2017

Margaret L Kripke

series ordinal

3

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17 August 2017

Honnavara N Ananthaswamy

series ordinal

4

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17 August 2017

publication date

1 January 2008

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Photochemistry and Photobiology

17 August 2017

published in

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17 August 2017

volume

84

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17 August 2017

issue

1

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17 August 2017

page(s)

55-62

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T antigen is bound to a host protein in SY40-transformed cells

17 August 2017

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21 January 2018

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21 January 2018

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The p53 tumour suppressor gene

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p53 function and dysfunction

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

21 January 2018

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21 January 2018

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

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The cellular response to p53: the decision between life and death

21 January 2018

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p53: at the crossroads of molecular carcinogenesis and risk assessment

21 January 2018

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21 January 2018

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21 January 2018

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p53, the cellular gatekeeper for growth and division

21 January 2018

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Central role of p53 in the suntan response and pathologic hyperpigmentation

21 January 2018

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p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes

21 January 2018

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Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

21 January 2018

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UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

21 January 2018

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p53-regulated apoptosis is differentiation dependent in ultraviolet B-irradiated mouse keratinocytes

21 January 2018

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Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skin

21 January 2018

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Loss of Fas-ligand expression in mouse keratinocytes during UV carcinogenesis

21 January 2018

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

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Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

21 January 2018

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Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation

21 January 2018

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Cooperative phosphorylation at multiple sites is required to activate p53 in response to UV radiation

21 January 2018

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Phosphorylation site interdependence of human p53 post-translational modifications in response to stress

21 January 2018

1 reference

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

p53-mediated protective responses to UV irradiation.

21 January 2018

1 reference

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The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

21 January 2018

1 reference

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A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

21 January 2018

1 reference

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Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients

21 January 2018

1 reference

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

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Tumor spectrum analysis in p53-mutant mice

21 January 2018

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p53 protects against skin cancer induction by UV-B radiation.

21 January 2018

1 reference

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Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Frequent clones of p53-mutated keratinocytes in normal human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Colonization of adjacent stem cell compartments by mutant keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Mechanism of insulin and IGF-I receptor activation and signal transduction specificity. Receptor dimer cross-linking, bell-shaped curves, and sustained versus transient signaling

21 January 2018

1 reference

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Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

UV-induced signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Platelet-activating factor, a molecular sensor for cellular damage, activates systemic immune suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Ultraviolet radiation induced signature mutations in photocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Ultraviolet irradiation-induced inflammation: effects of steroid and nonsteroid anti-inflammatory agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

The inhibiting effect of PABA on photocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

High sun protection factor sunscreens in the suppression of actinic neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Risk reduction for nonmelanoma skin cancer with childhood sunscreen use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Inhibition of solar simulator-induced p53 mutations and protection against skin cancer development in mice by sunscreens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Dissociation of Erythema and p53 Protein Expression in Human Skin Following UVB Irradiation, and Induction of p53 Protein and mRNA Following Application of Skin Irritants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-1097.2007.00213.X

10.1111/J.1751-1097.2007.00213.X

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference